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Title: Molecular rheostat for cofactor balance

Abstract

The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor regulatory system for cofactor utilization in the metabolic pathway.

Inventors:
; ;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1735203
Patent Number(s):
10760103
Application Number:
16/342,849
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AR0000556
Resource Type:
Patent
Resource Relation:
Patent File Date: 10/18/2017
Country of Publication:
United States
Language:
English

Citation Formats

Bowie, James U., Korman, Tyler P., and Opgenorth, Paul H. Molecular rheostat for cofactor balance. United States: N. p., 2020. Web.
Bowie, James U., Korman, Tyler P., & Opgenorth, Paul H. Molecular rheostat for cofactor balance. United States.
Bowie, James U., Korman, Tyler P., and Opgenorth, Paul H. Tue . "Molecular rheostat for cofactor balance". United States. https://www.osti.gov/servlets/purl/1735203.
@article{osti_1735203,
title = {Molecular rheostat for cofactor balance},
author = {Bowie, James U. and Korman, Tyler P. and Opgenorth, Paul H.},
abstractNote = {The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor regulatory system for cofactor utilization in the metabolic pathway.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {9}
}

Works referenced in this record:

Metabolic engineering of Corynebacterium glutamicum for increasing the production of l -ornithine by increasing NADPH availability
journal, October 2013


The Rhodococcus opacus TadD protein mediates triacylglycerol metabolism by regulating intracellular NAD(P)H pools
journal, January 2013


Improving poly-3-hydroxybutyrate production in Escherichia coli by combining the increase in the NADPH pool and acetyl-CoA availability
journal, February 2014


Two Glyceraldehyde-3-phosphate Dehydrogenases with Opposite Physiological Roles in a Nonphotosynthetic Bacterium
journal, May 2000