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Title: Producing adipic acid and related compounds using hybrid polyketide synthases

Abstract

The present invention provides for a polyketide synthase (PKS) capable of synthesizing a carboxylic acid, said PKS comprising a synthetic or hybrid module. The present invention also provides for a host cell comprising the PKS and when cultured produces the carboxylic acid. In some embodiments, the carboxylic acid is adipic acid.

Inventors:
; ; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1735202
Patent Number(s):
10760069
Application Number:
15/867,575
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 01/10/2018
Country of Publication:
United States
Language:
English

Citation Formats

Hagen, Andrew R., Poust, Sean, Katz, Leonard, and Keasling, Jay D. Producing adipic acid and related compounds using hybrid polyketide synthases. United States: N. p., 2020. Web.
Hagen, Andrew R., Poust, Sean, Katz, Leonard, & Keasling, Jay D. Producing adipic acid and related compounds using hybrid polyketide synthases. United States.
Hagen, Andrew R., Poust, Sean, Katz, Leonard, and Keasling, Jay D. Tue . "Producing adipic acid and related compounds using hybrid polyketide synthases". United States. https://www.osti.gov/servlets/purl/1735202.
@article{osti_1735202,
title = {Producing adipic acid and related compounds using hybrid polyketide synthases},
author = {Hagen, Andrew R. and Poust, Sean and Katz, Leonard and Keasling, Jay D.},
abstractNote = {The present invention provides for a polyketide synthase (PKS) capable of synthesizing a carboxylic acid, said PKS comprising a synthetic or hybrid module. The present invention also provides for a host cell comprising the PKS and when cultured produces the carboxylic acid. In some embodiments, the carboxylic acid is adipic acid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {9}
}

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