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Title: Microfluidic platform for multiplexed detection in single cells and methods thereof

Abstract

The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins, and post-translational modifications.

Inventors:
;
Issue Date:
Research Org.:
Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1735100
Patent Number(s):
10731205
Application Number:
15/925,389
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
NA0003525
Resource Type:
Patent
Resource Relation:
Patent File Date: 03/19/2018
Country of Publication:
United States
Language:
English

Citation Formats

Wu, Meiye, and Singh, Anup K. Microfluidic platform for multiplexed detection in single cells and methods thereof. United States: N. p., 2020. Web.
Wu, Meiye, & Singh, Anup K. Microfluidic platform for multiplexed detection in single cells and methods thereof. United States.
Wu, Meiye, and Singh, Anup K. Tue . "Microfluidic platform for multiplexed detection in single cells and methods thereof". United States. https://www.osti.gov/servlets/purl/1735100.
@article{osti_1735100,
title = {Microfluidic platform for multiplexed detection in single cells and methods thereof},
author = {Wu, Meiye and Singh, Anup K.},
abstractNote = {The present invention relates to a microfluidic device and platform configured to conduct multiplexed analysis within the device. In particular, the device allows multiple targets to be detected on a single-cell level. Also provided are methods of performing multiplexed analyses to detect one or more target nucleic acids, proteins, and post-translational modifications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {8}
}

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