Droplet array for single-cell analysis
Abstract
Techniques, systems, and devices are described for implementing a droplet array for single-cell analysis. A method of conducting single-cell analysis comprises generating a plurality of droplets, wherein each of the plurality of droplets contains a core material surrounded by a protective shell; loading the plurality of droplets, via a carrying fluid, onto an array including a plurality of trap structures, wherein the plurality of droplets are held by the plurality of trap structures; selecting a target droplet, held by a trap structure, from the plurality of droplets; and releasing the target droplet from the trap structure.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1735045
- Patent Number(s):
- 10718004
- Application Number:
- 15/385,799
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 12/20/2016
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Simon, Melinda, and Beer, N. Reginald. Droplet array for single-cell analysis. United States: N. p., 2020.
Web.
Simon, Melinda, & Beer, N. Reginald. Droplet array for single-cell analysis. United States.
Simon, Melinda, and Beer, N. Reginald. Tue .
"Droplet array for single-cell analysis". United States. https://www.osti.gov/servlets/purl/1735045.
@article{osti_1735045,
title = {Droplet array for single-cell analysis},
author = {Simon, Melinda and Beer, N. Reginald},
abstractNote = {Techniques, systems, and devices are described for implementing a droplet array for single-cell analysis. A method of conducting single-cell analysis comprises generating a plurality of droplets, wherein each of the plurality of droplets contains a core material surrounded by a protective shell; loading the plurality of droplets, via a carrying fluid, onto an array including a plurality of trap structures, wherein the plurality of droplets are held by the plurality of trap structures; selecting a target droplet, held by a trap structure, from the plurality of droplets; and releasing the target droplet from the trap structure.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {7}
}
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patent-application, February 2011
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High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation
patent, November 2015
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