Aqueous carrier waveguide in a flow cytometer

Mariella, R P; Engh, G van den; Northrup, M A

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A - human necessities
A01 - agriculture
A21 - baking
A22 - butchering
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A24 - tobacco
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A42 - headwear
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A44 - haberdashery
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A47 - furniture
A61 - medical or veterinary science
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A99 - subject matter not otherwise provided for in this section
B - performing operations
B01 - physical or chemical processes or apparatus in general
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B03 - separation of solid materials using liquids or using pneumatic tables or jigs
B04 - centrifugal apparatus or machines for carrying-out physical or chemical processes
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D10 - indexing scheme associated with sublasses of section d, relating to textiles
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Title: Aqueous carrier waveguide in a flow cytometer

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Abstract

The liquid of a flow cytometer itself acts as an optical waveguide, thus transmitting the light to an optical filter/detector combination. This alternative apparatus and method for detecting scattered light in a flow cytometer is provided by a device which views and detects the light trapped within the optical waveguide formed by the flow stream. A fiber optic or other light collecting device is positioned within the flow stream. This provides enormous advantages over the standard light collection technique which uses a microscope objective. The signal-to-noise ratio is greatly increased over that for right-angle-scattered light collected by a microscope objective, and the alignment requirements are simplified. 6 figs.

Inventors:: Mariella, Jr, R P; Engh, G van den; Northrup, M A

Issue Date:: 1995-12-12

Research Org.:: Univ. of California (United States)

OSTI Identifier:: 170469

Patent Number(s):: 5475487

Application Number:: PAN: 8-230,077

Assignee:: Univ. of California, Oakland, CA (United States)

DOE Contract Number:: W-7405-ENG-48

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 12 Dec 1995

Country of Publication:: United States

Language:: English

Subject:: 55 BIOLOGY AND MEDICINE, BASIC STUDIES; CELL FLOW SYSTEMS; LIGHT SCATTERING; OPTICAL EQUIPMENT; DESIGN; FIBER OPTICS

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                    Mariella, Jr, R P, Engh, G van den, and Northrup, M A. Aqueous carrier waveguide in a flow cytometer.  United States: N. p., 1995. 
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                    Mariella, Jr, R P, Engh, G van den, & Northrup, M A. Aqueous carrier waveguide in a flow cytometer.  United States.

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                    Mariella, Jr, R P, Engh, G van den, and Northrup, M A. Tue .  
        "Aqueous carrier waveguide in a flow cytometer".  United States.

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@article{osti_170469,

  title        = {Aqueous carrier waveguide in a flow cytometer},

  author       = {Mariella, Jr, R P and Engh, G van den and Northrup, M A},

  abstractNote = {The liquid of a flow cytometer itself acts as an optical waveguide, thus transmitting the light to an optical filter/detector combination. This alternative apparatus and method for detecting scattered light in a flow cytometer is provided by a device which views and detects the light trapped within the optical waveguide formed by the flow stream. A fiber optic or other light collecting device is positioned within the flow stream. This provides enormous advantages over the standard light collection technique which uses a microscope objective. The signal-to-noise ratio is greatly increased over that for right-angle-scattered light collected by a microscope objective, and the alignment requirements are simplified. 6 figs.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1995},

  month        = {12}

}

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