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Title: Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same

Abstract

Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula

Inventors:
; ; ;
Issue Date:
Research Org.:
Univ. of Southern California, Los Angeles, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1650874
Patent Number(s):
10646598
Application Number:
15/194,425
Assignee:
University of Southern California (Los Angeles, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Resource Type:
Patent
Resource Relation:
Patent File Date: 06/27/2016
Country of Publication:
United States
Language:
English

Citation Formats

Conti, Peter S., Cai, Hancheng, Li, Zibo, and Liu, Shuanglong. Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same. United States: N. p., 2020. Web.
Conti, Peter S., Cai, Hancheng, Li, Zibo, & Liu, Shuanglong. Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same. United States.
Conti, Peter S., Cai, Hancheng, Li, Zibo, and Liu, Shuanglong. Tue . "Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same". United States. https://www.osti.gov/servlets/purl/1650874.
@article{osti_1650874,
title = {Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same},
author = {Conti, Peter S. and Cai, Hancheng and Li, Zibo and Liu, Shuanglong},
abstractNote = {Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {5}
}

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Method for labeling antibodies with a metal ion
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Metal radionuclide labeled proteins for diagnosis and therapy
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Metal radionuclide labeled proteins for diagnosis and therapy
patent, September 1993


Methods and compositions for positron emission tomography myocardial perfusion imaging
patent, October 2017


Cryptate compounds and methods for diagnosis and therapy
patent, March 2005