Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same
Abstract
Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Southern California, Los Angeles, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1650874
- Patent Number(s):
- 10646598
- Application Number:
- 15/194,425
- Assignee:
- University of Southern California (Los Angeles, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 06/27/2016
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
Citation Formats
Conti, Peter S., Cai, Hancheng, Li, Zibo, and Liu, Shuanglong. Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same. United States: N. p., 2020.
Web.
Conti, Peter S., Cai, Hancheng, Li, Zibo, & Liu, Shuanglong. Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same. United States.
Conti, Peter S., Cai, Hancheng, Li, Zibo, and Liu, Shuanglong. Tue .
"Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same". United States. https://www.osti.gov/servlets/purl/1650874.
@article{osti_1650874,
title = {Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same},
author = {Conti, Peter S. and Cai, Hancheng and Li, Zibo and Liu, Shuanglong},
abstractNote = {Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {5}
}
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Works referenced in this record:
Metal radionuclide labeled proteins for diagnosis and therapy
patent, September 1993
- Fritzberg, Alan R.; Kasina, Sudhakar; Srinivasan, Ananthachari
- US Patent Document 5,242,679
Cage-like bifunctional chelators, copper-64 radiopharmaceuticals and PET imaging using the same
patent, August 2016
- Conti, Peter S.; Cai, Hancheng; Li, Zibo
- US Patent Document 9,403,875
Cryptate compounds and methods for diagnosis and therapy
patent, March 2005
- Smith, Suzanne V.; Harrowfield, John M.; Di Bartolo, Nadine M.
- US Patent Document 6,869,589
Method for labeling antibodies with a metal ion
patent, October 1991
- Pak, Koon Y.; Dean, Richard T.; Mattis, Jeffrey A.
- US Patent Document 5,053,493
Metal radionuclide labeled proteins for diagnosis and therapy
patent, December 1992
- Fritzberg, Alan R.; Kasina, Sudhakar; Srinivasan, Ananthachari
- US Patent Document 5,175,343
Methods and compositions for the rapid synthesis of radiometal-labeled probes
patent, September 2016
- Chen, Kai; Conti, Peter S.
- US Patent Document 9,447,149
Methods and compositions for positron emission tomography myocardial perfusion imaging
patent, October 2017
- Conti, Peter S.; Liu, Shuanglong; Li, Zibo
- US Patent Document 9,789,211