ION focusing

Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

Title: ION focusing

Abstract

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

Inventors:: Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

Issue Date:: 2020-04-07

Research Org.:: Purdue Univ., West Lafayette, IN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1650748

Patent Number(s):: 10615021

Application Number:: 16/000,526

Assignee:: Purdue Research Foundation (West Lafayette, IN)

Patent Classifications (CPCs):: H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

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H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/06 - Electron- or ion-optical arrangements
H01J49/067 - {Ion lenses, apertures, skimmers}
H01J49/10 - Ion sources
H01J49/165 - {Electrospray ionisation}
H01J49/26 - Mass spectrometers or separator tubes

Show less

DOE Contract Number:: FG02-06ER15807

Resource Type:: Patent

Resource Relation:: Patent File Date: 06/05/2018

Country of Publication:: United States

Language:: English

Subject:: 75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY

Citation Formats


                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. ION focusing.  United States: N. p., 2020. 
        Web.

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                    Cooks, Robert Graham, Baird, Zane, & Peng, Wen-Ping. ION focusing.  United States.

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                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. Tue .  
        "ION focusing".  United States.  https://www.osti.gov/servlets/purl/1650748.

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@article{osti_1650748,

  title        = {ION focusing},

  author       = {Cooks, Robert Graham and Baird, Zane and Peng, Wen-Ping},

  abstractNote = {The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2020},

  month        = {4}

}

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Title: ION focusing

Abstract

Citation Formats

Electrospray ionization ion source with tunable charge reduction patent-application, May 2007

Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method patent-application, June 2012

Modulation of molecular interaction sites on RNA and other biomolecules patent-application, January 2003

Discontinuous atmospheric pressure interface patent, November 2012

Ion focusing patent-application, June 2016

Mass spectrometry Probes and Systems for Ionizing a Sample Transport patent-application, October 2016

Method and system for desorption atmospheric pressure chemical ionization patent, June 2009

Electro-Dynamic or Electro-Static Lens Coupled to a Stacked Ring Ion Guide patent-application, April 2010

Laminated tube for the transport of charged particles contained in a gaseous medium patent, September 2005

Spherical side-to-side FAIMS patent-application, December 2003

Ion Focusing patent-application, May 2015

“Droplet pickup ion source” coupled to mobility analyzer apparatus and method patent, August 2010

Method and system for desorption electrospray ionization patent, February 2008

Apparatus and methods for analyzing ions patent, January 2013

Ion focusing patent, November 2015

Ion transport device and modes of operation thereof patent, August 2010

Method and device for non-contact sampling and detection patent, September 2009

System and Method of Computing and Rendering the Nature of Dipole Moments, Condensed Matter, and Reaction Kinetics patent-application, May 2010

Method and system for desorption electrospray ionization patent-application, October 2005

Method and apparatus for aerodynamic ion focusing patent, January 2006

Sample Analysis Systems and Methods of Use Thereof patent-application, April 2017

Time-of-Flight Mass Spectrometry of Surfaces patent-application, July 2009

Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation patent-application, December 2002

Sample analysis systems and methods of use thereof patent, July 2017

Segmented side-to-side FAIMS patent-application, July 2005

Integrated ion focusing and gating optics for ion trap mass spectrometer patent-application,

Synchronization of Ion Generation with Cycling of a Discontinuous Atmospheric Interface patent-application, April 2016

Electron emitting construct configured with ion bombardment resistant patent, April 2019

Systems and methods for transfer of ions for analysis patent, April 2013

Charge reduction electrospray ionization ion source patent-application, September 2002

Systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions patent-application, March 2015

Ion focusing patent, January 2017

Direct Sample Analysis Ion Source patent-application, December 2012

Microengineered vacuum interface for an ionization system patent, August 2010

Atmospheric pressure interface ion source and mass spectrometer patent-application, May 2014

Low Cross-Talk Fast Sample Delivery System Based Upon Acoustic Droplet Ejection patent-application, October 2014

Apparatus and method for focusing ions and charged particles at atmospheric pressure patent, June 2004

System and method for the preparation of arrays of biological or other molecules patent, April 2008

FAIMS apparatus having plural ion inlets and method therefore patent-application, November 2004

Time-of-Flight Spectrometry and Spectroscopy of Surfaces patent-application, June 2011

Method and apparatus for ion mobility spectrometry with alignment of dipole direction (IMS-ADD) patent-application, October 2006

Enclosed desorption electrospray ionization patent-application, July 2008

Coupling Differential Mobility Based Ambient Pressure Ion Prefiltering and Ion Focusing at Low Flow Rates for a Portable Mass Spectrometer patent-application, May 2011

High-speed molecular analyzer system and method patent-application, April 2009

Electrospray ionization ion source with tunable charge reduction
patent-application, May 2007

Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method
patent-application, June 2012

Modulation of molecular interaction sites on RNA and other biomolecules
patent-application, January 2003

Discontinuous atmospheric pressure interface
patent, November 2012

Ion focusing
patent-application, June 2016

Mass spectrometry Probes and Systems for Ionizing a Sample Transport
patent-application, October 2016

Method and system for desorption atmospheric pressure chemical ionization
patent, June 2009

Electro-Dynamic or Electro-Static Lens Coupled to a Stacked Ring Ion Guide
patent-application, April 2010

Laminated tube for the transport of charged particles contained in a gaseous medium
patent, September 2005

Spherical side-to-side FAIMS
patent-application, December 2003

Ion Focusing
patent-application, May 2015

“Droplet pickup ion source” coupled to mobility analyzer apparatus and method
patent, August 2010

Method and system for desorption electrospray ionization
patent, February 2008

Apparatus and methods for analyzing ions
patent, January 2013

Ion focusing
patent, November 2015

Ion transport device and modes of operation thereof
patent, August 2010

Method and device for non-contact sampling and detection
patent, September 2009

System and Method of Computing and Rendering the Nature of Dipole Moments, Condensed Matter, and Reaction Kinetics
patent-application, May 2010

Method and system for desorption electrospray ionization
patent-application, October 2005

Method and apparatus for aerodynamic ion focusing
patent, January 2006

Sample Analysis Systems and Methods of Use Thereof
patent-application, April 2017

Time-of-Flight Mass Spectrometry of Surfaces
patent-application, July 2009

Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation
patent-application, December 2002

Sample analysis systems and methods of use thereof
patent, July 2017

Segmented side-to-side FAIMS
patent-application, July 2005

Integrated ion focusing and gating optics for ion trap mass spectrometer
patent-application,

Synchronization of Ion Generation with Cycling of a Discontinuous Atmospheric Interface
patent-application, April 2016

Electron emitting construct configured with ion bombardment resistant
patent, April 2019

Systems and methods for transfer of ions for analysis
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Charge reduction electrospray ionization ion source
patent-application, September 2002

Systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions
patent-application, March 2015

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patent, January 2017

Direct Sample Analysis Ion Source
patent-application, December 2012

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patent, August 2010

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patent-application, May 2014

Low Cross-Talk Fast Sample Delivery System Based Upon Acoustic Droplet Ejection
patent-application, October 2014

Apparatus and method for focusing ions and charged particles at atmospheric pressure
patent, June 2004

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patent, April 2008

FAIMS apparatus having plural ion inlets and method therefore
patent-application, November 2004

Time-of-Flight Spectrometry and Spectroscopy of Surfaces
patent-application, June 2011

Method and apparatus for ion mobility spectrometry with alignment of dipole direction (IMS-ADD)
patent-application, October 2006

Enclosed desorption electrospray ionization
patent-application, July 2008

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patent-application, May 2011

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