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Title: Open port sampling interface

Abstract

A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end.

Inventors:
Issue Date:
Research Org.:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632634
Patent Number(s):
10578593
Application Number:
16/058,663
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 08/08/2018
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Van Berkel, Gary J. Open port sampling interface. United States: N. p., 2020. Web.
Van Berkel, Gary J. Open port sampling interface. United States.
Van Berkel, Gary J. Tue . "Open port sampling interface". United States. https://www.osti.gov/servlets/purl/1632634.
@article{osti_1632634,
title = {Open port sampling interface},
author = {Van Berkel, Gary J.},
abstractNote = {A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {3}
}

Works referenced in this record:

Ball Assisted Device for Analytical Surface Sampling
patent-application, April 2014


Open Probe Method and Device for Sample Introduction for Mass Spectrometry Analysis
patent-application, January 2010


Ball assisted device for analytical surface sampling
patent, November 2015


Sample collection vessel extender for chromatographic systems
patent-application, May 2004


Systems and Methods for Laser Assisted sample Transfer to Solution for Chemical Analysis
patent-application, August 2014


Ionization Method and Apparatus Using Electrospray
patent-application, June 2009


System and Method for Extracting a Sample from a Surface
patent-application, November 2011


Laser desorption - electrospray ion (ESI) source for mass spectrometers
patent-application, November 2008


High-temperature characterization of polymers
patent, July 2001


Sampling probe for microarray read out using electrospray mass spectrometry
patent-application, October 2003


Electrospray ion source with reduced analyte electrochemistry
patent, August 2011


Miniaturized fluid transfer device
patent, November 2002


Capture Probe
patent-application, October 2016


Fluid Sample Analysis System
patent, April 1974


Enhanced spot preparation for liquid extractive sampling and analysis
patent, September 2015


Surface Sampling Concentration and Reaction Probe
patent-application, April 2012


Blood separation device
patent, August 1999


Method and System for Formation and Withdrawal of a Sample from a Surface to be Analyzed
patent-application, August 2014


Spatially resolved thermal desorption/ionization coupled with mass spectrometry
patent, February 2013


Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, August 2013


Interface members and holders for microfluidic array devices
patent-application, February 2004


Automated position control of a surface array relative to a liquid microjunction surface sampler
patent, November 2007


Thin-channel electrospray emitter
patent, August 2004


High heating rate thermal desorption for molecular surface sampling
patent, March 2016


System and method for extracting a sample from a surface
patent, June 2015


Charged droplet spray probe
patent-application, November 2005


Liquid Chromatograph
patent-application, July 2011


Open port sampling interface
patent, April 2017


Surface sampling concentration and reaction probe
patent, July 2013


Sample handling system with solvent washing
patent-application, August 2004


Quantitative Analysis of Surface-Derived Samples using Mass Spectrometry
patent-application, November 2007


Transmission geometry laser ablation into a non-contact liquid vortex capture probe for mass spectrometry imaging
journal, June 2014

  • Ovchinnikova, Olga S.; Bhandari, Deepak; Lorenz, Matthias
  • Rapid Communications in Mass Spectrometry, Vol. 28, Issue 15, p. 1665-1673
  • https://doi.org/10.1002/rcm.6946

A Falling Drop for Sample Injection in Capillary Zone Electrophoresis
journal, March 1997


Mass Spectrometry With Laser Ablation
patent-application, June 2008


An open port sampling interface for liquid introduction atmospheric pressure ionization mass spectrometry: Open port sampling interface
journal, August 2015


Systems and Methods for Laser Assisted Sample Transfer to Solution for Chemical Analysis
patent-application, April 2012


Nozzle for DNP Polarizer
patent-application, February 2011


Syringe with bubble flushing
patent, July 1996


Open Port Sampling Interface
patent-application, October 2016


Method and system for formation and withdrawal of a sample from a surface to be analyzed
patent-application, September 2010


Systems and methods for laser assisted sample transfer to solution for chemical analysis
patent, June 2014