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Title: Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules

Abstract

This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Wisconsin Alumni Research Foundation, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632612
Patent Number(s):
10571460
Application Number:
15/600,352
Assignee:
Wisconsin Alumni Research Foundation (Madison, WI)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
FG02-88ER13938
Resource Type:
Patent
Resource Relation:
Patent File Date: 05/19/2017
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Sussman, Michael R., Shohet, J. Leon, Choudhury, Faraz A., Blatz, Joshua M., Minkoff, Benjamin B., and Benjamin, Daniel I. Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules. United States: N. p., 2020. Web.
Sussman, Michael R., Shohet, J. Leon, Choudhury, Faraz A., Blatz, Joshua M., Minkoff, Benjamin B., & Benjamin, Daniel I. Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules. United States.
Sussman, Michael R., Shohet, J. Leon, Choudhury, Faraz A., Blatz, Joshua M., Minkoff, Benjamin B., and Benjamin, Daniel I. Tue . "Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules". United States. https://www.osti.gov/servlets/purl/1632612.
@article{osti_1632612,
title = {Methods, systems, and compositions for studying solvent accessibility and three-dimensional structure of biological molecules},
author = {Sussman, Michael R. and Shohet, J. Leon and Choudhury, Faraz A. and Blatz, Joshua M. and Minkoff, Benjamin B. and Benjamin, Daniel I.},
abstractNote = {This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {2}
}

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Works referenced in this record:

Immunoglobulin superfamily domains and fragments with increased solubility
patent, November 2004