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Title: Multi-organ media compositions and methods of their use

Abstract

Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632572
Patent Number(s):
10564148
Application Number:
15/513,948
Assignee:
Triad National Security, LLC (Los Alamos, NM); CFD Research Corporation (Huntsville, AL)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/24/2015
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States: N. p., 2020. Web.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, & Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Tue . "Multi-organ media compositions and methods of their use". United States. https://www.osti.gov/servlets/purl/1632572.
@article{osti_1632572,
title = {Multi-organ media compositions and methods of their use},
author = {Iyer, Rashi and Harris, Jennifer F. and Huang, Jen-Huang and Nath, Pulak and Przekwas, Andrzej},
abstractNote = {Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {2}
}

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