Multi-organ media compositions and methods of their use
Abstract
Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1632572
- Patent Number(s):
- 10564148
- Application Number:
- 15/513,948
- Assignee:
- Triad National Security, LLC (Los Alamos, NM); CFD Research Corporation (Huntsville, AL)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 09/24/2015
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States: N. p., 2020.
Web.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, & Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Tue .
"Multi-organ media compositions and methods of their use". United States. https://www.osti.gov/servlets/purl/1632572.
@article{osti_1632572,
title = {Multi-organ media compositions and methods of their use},
author = {Iyer, Rashi and Harris, Jennifer F. and Huang, Jen-Huang and Nath, Pulak and Przekwas, Andrzej},
abstractNote = {Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 18 00:00:00 EST 2020},
month = {Tue Feb 18 00:00:00 EST 2020}
}
Works referenced in this record:
Method and apparatus for analyte processing
patent-application, October 2012
- Masters, Brett; France, Eric; Falb, Peter Wight
- US Patent Application 13/525995; 20120263631
Fluidics devices
patent, January 2011
- Clemens, Charles E.; Mucic, Robert; Montalvo, Rudolph A.
- US Patent Document 7,863,035
Chemically defined medium for cultured mammalian cells
patent, May 2005
- Lee, Chichang; Ly, Celia; Moore, Gordon
- US Patent Document 6,900,056
Model Epithelial Cell Cultures
patent-application, June 2004
- Lin, Yi-Chan James; Tam, Yun Kau; Semple, Hugh Alexander
- US Patent Application 10/648081; 20040115801
Integrated Organ-on-Chip Systems and Applications of the Same
patent-application, December 2014
- Wikswo, John P.; Cliffel, David E.; Markov, Dmitry A.
- US Patent Application 14/363074; 20140356849
Dry Powder Cell Culture Products and Methods of Production Thereof
patent-application, January 2008
- Fike, Richard M.; Whitford, William; Hassett, Richard F.
- US Patent Application 11/669827; 20080019883
Microfluidics, Lung Surfactant, and Respiratory Disorders
journal, April 2009
- Tavana, Hossein; Huh, Dongeun; Grotberg, James B.
- Laboratory Medicine, Vol. 40, Issue 4
Preparation of Fibroblast-Populated Connective Tissue Substitute
patent-application, January 2009
- Gibbs, Susan; De Boer, Edith Margaretha; Kirtschig, Gudula
- US Patent Application 10/585299; 20090016994
Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume
patent-application, October 2013
- Vickers, Andrew J.; Scardino, Peter T.; Lija, Hans
- US Patent Application 13/785058; 20130273643
In vitro model for pathological or physiologic conditions
patent-application, November 2013
- Blackman, Brett R.; Wamhoff, Brian R.; Dash, Ajit
- US Patent Application 13/866017; 20130309677
Tolerance-Induced Targeted Antibody Production
patent-application, February 2007
- Michl, Josef; Bradu, Stefan M.
- US Patent Application 10/542586; 20070036809
Culture Medium Optimization for Photosynthetic Bacteria
journal, June 2010
- Zhao, Wei; He, Chun Hua; Zhang, Gaung Ming
- Advanced Materials Research, Vol. 113-116
Serum-free medium for culturing animal cells
patent, June 2002
- Shibuya, Kazushi; Atsumi, Masaru; Tsunakawa, Shigeyuki
- US Patent Document 6,406,909
Method for culturing Chinese hamster ovary cells
patent, May 1997
- Keen, Michael J.; Rapson, Nicholas T.
- US Patent Document 5,633,162
Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof
patent-application, May 2012
- Shuler, Michael L.; Sung, Jong Hwan
- US Patent Application 13/387585; 20120135452
Vascularized perfused microtissue/micro-organ arrays
patent, March 2001
- Griffith, Linda G.; Tannenbaum, Steven R.; Powers, Mark
- US Patent Document 6,197,575
Fluidic Devices with Diaphragm Valves
patent-application, December 2010
- Blaga, Iuliu I.; Jovanovich, Stevan B.; Kobrin, Boris
- US Patent Application 12/789186; 20100303687
Container for dispensing a liquid and method of using the same
patent-application, March 2005
- Jeter, Michael
- US Patent Application 10/943554; 20050051449
Antibiotic complex
patent, August 1978
- Kawaguchi, Hiroshi; Tomita, Koji; Fujisawa, Kei-ichi
- US Patent Document 4,108,725
Artificial lung system and its use
patent-application, November 2007
- Fischer, Stefan; Matheis, Georg
- US Patent Application 11/788579; 20070276508
Human breast epithelial cell type with stem cell and luminal epithelial cell characteristics
patent, July 1997
- Chang, Chia-Cheng; Trosko, James
- US Patent Document 5,650,317
Integrated human organ-on-chip microphysiological systems
patent-application, January 2015
- Wikswo, John P.; Samson, Philip C.; Block, III, Frank Emmanuel
- US Patent Application 14/362841; 20150004077
Micro-organ device
patent, November 2013
- Gonda, Steve R.; Chang, Robert C.; Starly, Binil
- US Patent Document 8,580,546
Fibronectin type III domain based scaffold compositions, methods and uses
patent, October 2012
- Jacobs, Steven; O'Neil, Karyn
- US Patent Document 8,278,419
Microfluidic devices, particularly filtration devices comprising polymeric membranes, and methods for their manufacture and use
patent-application, March 2012
- Jovanovic, Goran; Atre, Sundar V.; Paul, Brian Kevin
- US Patent Application 13/292903; 20120074062
Smart disposable plastic lab-on-a-chip for point-of-care testing
patent-application, June 2005
- Ahn, Chong H.; Choi, Jin-Woo; Beaucage, Gregory
- US Patent Application 10/947577; 20050130292
Liquid container with integrated straw
patent-application, September 2011
- Lee, Tzu-Kang
- US Patent Application 12/719196; 20110215107
Compositions and methods for culturing cells from normal human tubo-ovarian epithelium and human tubo-ovarian tumors
patent-application, June 2014
- Ince, Tan A.
- US Patent Application 14/007008; 20140170693