DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Multi-organ media compositions and methods of their use

Abstract

Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632572
Patent Number(s):
10564148
Application Number:
15/513,948
Assignee:
Triad National Security, LLC (Los Alamos, NM); CFD Research Corporation (Huntsville, AL)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/24/2015
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States: N. p., 2020. Web.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, & Przekwas, Andrzej. Multi-organ media compositions and methods of their use. United States.
Iyer, Rashi, Harris, Jennifer F., Huang, Jen-Huang, Nath, Pulak, and Przekwas, Andrzej. Tue . "Multi-organ media compositions and methods of their use". United States. https://www.osti.gov/servlets/purl/1632572.
@article{osti_1632572,
title = {Multi-organ media compositions and methods of their use},
author = {Iyer, Rashi and Harris, Jennifer F. and Huang, Jen-Huang and Nath, Pulak and Przekwas, Andrzej},
abstractNote = {Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 18 00:00:00 EST 2020},
month = {Tue Feb 18 00:00:00 EST 2020}
}

Works referenced in this record:

Method and apparatus for analyte processing
patent-application, October 2012


Fluidics devices
patent, January 2011


Chemically defined medium for cultured mammalian cells
patent, May 2005


Model Epithelial Cell Cultures
patent-application, June 2004


Integrated Organ-on-Chip Systems and Applications of the Same
patent-application, December 2014


Dry Powder Cell Culture Products and Methods of Production Thereof
patent-application, January 2008


Microfluidics, Lung Surfactant, and Respiratory Disorders
journal, April 2009


Preparation of Fibroblast-Populated Connective Tissue Substitute
patent-application, January 2009


Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume
patent-application, October 2013


In vitro model for pathological or physiologic conditions
patent-application, November 2013


Tolerance-Induced Targeted Antibody Production
patent-application, February 2007


Culture Medium Optimization for Photosynthetic Bacteria
journal, June 2010


Serum-free medium for culturing animal cells
patent, June 2002


Method for culturing Chinese hamster ovary cells
patent, May 1997


Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof
patent-application, May 2012


Vascularized perfused microtissue/micro-organ arrays
patent, March 2001


Fluidic Devices with Diaphragm Valves
patent-application, December 2010


Container for dispensing a liquid and method of using the same
patent-application, March 2005


Antibiotic complex
patent, August 1978


Artificial lung system and its use
patent-application, November 2007


Integrated human organ-on-chip microphysiological systems
patent-application, January 2015


Micro-organ device
patent, November 2013


Culture media for mammalian cells
patent, July 1994


Microfluidic devices, particularly filtration devices comprising polymeric membranes, and methods for their manufacture and use
patent-application, March 2012


Smart disposable plastic lab-on-a-chip for point-of-care testing
patent-application, June 2005


Liquid container with integrated straw
patent-application, September 2011