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Title: Shape-preserving polymeric replication of biological matter

Abstract

The present invention relates to a method of forming silica nanolayers on or within a biological sample, thereby capturing structural details that are present in the sample. The resultant silica composite or silica replica, in turn, can be employed as a template for a replica having those structural details captured in a polymer. Also provided herein are synthetic constructs including a polymeric replica, which can have any useful feature (e.g., oxygen-binding capacity).

Inventors:
Issue Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632462
Patent Number(s):
10538632
Application Number:
15/282,511
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/30/2016
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 77 NANOSCIENCE AND NANOTECHNOLOGY; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Kaehr, Bryan James. Shape-preserving polymeric replication of biological matter. United States: N. p., 2020. Web.
Kaehr, Bryan James. Shape-preserving polymeric replication of biological matter. United States.
Kaehr, Bryan James. Tue . "Shape-preserving polymeric replication of biological matter". United States. https://www.osti.gov/servlets/purl/1632462.
@article{osti_1632462,
title = {Shape-preserving polymeric replication of biological matter},
author = {Kaehr, Bryan James},
abstractNote = {The present invention relates to a method of forming silica nanolayers on or within a biological sample, thereby capturing structural details that are present in the sample. The resultant silica composite or silica replica, in turn, can be employed as a template for a replica having those structural details captured in a polymer. Also provided herein are synthetic constructs including a polymeric replica, which can have any useful feature (e.g., oxygen-binding capacity).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {1}
}

Patent:

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Works referenced in this record:

Prototyping of patterned functional nanostructures
patent, October 2002


Composition containing aerogel substrate loaded with tritium
patent, January 1992


Inorganic dual-layer microporous supported membranes
patent, March 2003


Sol-gel method for encapsulating molecules
patent, December 2002


Photo-definable self-assembled materials
patent, February 2008


Cell-based composite materials with programmed structures and functions
patent, March 2016


Hollow sphere metal oxides
patent, June 2010


Solid-state radiation-emitting compositions and devices
patent, August 1992


Luminescent light source for laser pumping and laser system containing same
patent, May 1994


Preparation of hydrophobic coatings
patent, February 2009


Method for making surfactant-templated thin films
patent, August 2010


Prototyping of patterned functional nanostructures
patent, July 2005


Method to create gradient index in a polymer
patent, October 2014


Molecular receptors in metal oxide sol-gel materials prepared via molecular imprinting
patent, May 2000


Inorganic volumetric light source excited by ultraviolet light
patent, April 1994


Molecular sieving silica membrane fabrication process
patent, August 1999


Solid-state radiation-emitting compositions and devices
patent, June 1992


Aerosol method for nano silver-silica composite anti-microbial agent
patent, August 2012


Ultra-thin microporous/hybrid materials
patent, May 2012


Methods for preparing high crystallinity and surface area porous metal oxides
patent, November 2012


Method for making surfactant-templated, high-porosity thin films
patent, August 2001


Method for making surfactant-templated thin films
patent, May 2002


Molecular sieve sensors for selective detection at the nanogram level
patent, September 1992


Photo-definable self-assembled materials
patent, October 2004


Process to form mesostructured films
patent, January 1999


Method for net-shaping using aerogels
patent, July 2001


Process for making solid-state radiation-emitting composition
patent, August 1993


Molecular sieving silica membrane fabrication process
patent, June 1998


Fluid light guide having hydrophobic aerogel cladding layer
patent, January 2006


Freezing assisted fabrication of nano and micro hollow cubic metal oxides
patent, August 2013


Durable polymer-aerogel based superhydrophobic coatings, a composite material
patent, March 2014


Self-assembly of nanocomposite materials
patent, July 2001


Coatings with controlled porosity and chemical properties
patent, July 1993


Self-assembly of water-soluble nanocrystals
patent, January 2012


Shape-preserving transformations of organic matter and compositions thereof
patent, June 2018


Preparation of high porosity xerogels by chemical surface modification.
patent, October 1996


Coatings with controlled porosity and chemical properties
patent, December 1996


Porous nanoparticle supported lipid bilayer nanostructures
patent, May 2014


Supported inorganic membranes
patent, June 1998


Uncooled thin film pyroelectric IR detector with aerogel thermal isolation
patent, September 1999