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Title: Ultrasonic analyte concentration and application in flow cytometry

Abstract

The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.

Inventors:
; ; ; ; ; ;
Issue Date:
Research Org.:
Triad National Security, LLC, Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632452
Patent Number(s):
10537831
Application Number:
14/729,244
Assignee:
Triad National Security, LLC (Los Alamos, NM)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
89233218CNA000001
Resource Type:
Patent
Resource Relation:
Patent File Date: 06/03/2015
Country of Publication:
United States
Language:
English

Citation Formats

Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, and Graves, Steven. Ultrasonic analyte concentration and application in flow cytometry. United States: N. p., 2020. Web.
Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, & Graves, Steven. Ultrasonic analyte concentration and application in flow cytometry. United States.
Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, and Graves, Steven. Tue . "Ultrasonic analyte concentration and application in flow cytometry". United States. https://www.osti.gov/servlets/purl/1632452.
@article{osti_1632452,
title = {Ultrasonic analyte concentration and application in flow cytometry},
author = {Kaduchak, Gregory and Goddard, Greg and Salzman, Gary and Sinha, Dipen and Martin, John C. and Kwiatkowski, Christopher and Graves, Steven},
abstractNote = {The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {1}
}

Patent:

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