Xylose utilizing oleaginous yeast
Abstract
Presented herein are oleaginous strains of yeast such as Saccharomyces cerevisiae that have been modified to allow for xylose utilization. Such strains are also modified to allow for higher lipid accumulation utilizing a broad range of sugar monomers such as those released during pretreatment and enzymatic saccharification of lignocellulosic biomass. Methods of producing lipids and ethanol using these yeast strains are also disclosed.
- Inventors:
- Issue Date:
- Research Org.:
- National Renewable Energy Laboratory (NREL), Golden, CO (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1632427
- Patent Number(s):
- 10533196
- Application Number:
- 15/282,591
- Assignee:
- Alliance for Sustainable Energy, LLC (Golden, CO)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC36-08GO28308
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 09/30/2016
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 09 BIOMASS FUELS
Citation Formats
Knoshaug, Eric P., Zhang, Min, Singh, Arjun, and Guarnieri, Michael T. Xylose utilizing oleaginous yeast. United States: N. p., 2020.
Web.
Knoshaug, Eric P., Zhang, Min, Singh, Arjun, & Guarnieri, Michael T. Xylose utilizing oleaginous yeast. United States.
Knoshaug, Eric P., Zhang, Min, Singh, Arjun, and Guarnieri, Michael T. Tue .
"Xylose utilizing oleaginous yeast". United States. https://www.osti.gov/servlets/purl/1632427.
@article{osti_1632427,
title = {Xylose utilizing oleaginous yeast},
author = {Knoshaug, Eric P. and Zhang, Min and Singh, Arjun and Guarnieri, Michael T.},
abstractNote = {Presented herein are oleaginous strains of yeast such as Saccharomyces cerevisiae that have been modified to allow for xylose utilization. Such strains are also modified to allow for higher lipid accumulation utilizing a broad range of sugar monomers such as those released during pretreatment and enzymatic saccharification of lignocellulosic biomass. Methods of producing lipids and ethanol using these yeast strains are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {1}
}
Works referenced in this record:
Snf1 Is a Regulator of Lipid Accumulation in Yarrowia lipolytica
journal, September 2013
- Seip, John; Jackson, Raymond; He, Hongxian
- Applied and Environmental Microbiology, Vol. 79, Issue 23
Anaerobic Xylose Fermentation by Recombinant Saccharomyces cerevisiae Carrying XYL1, XYL2, and XKS1 in Mineral Medium Chemostat Cultures
journal, August 2000
- Eliasson, A.; Christensson, C.; Wahlbom, C. F.
- Applied and Environmental Microbiology, Vol. 66, Issue 8
The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response inSaccharomyces cerevisiae
journal, June 2011
- Hickman, Mark J.; Spatt, Dan; Winston, Fred
- Genetics, Vol. 188, Issue 2
Overexpression of the active diacylglycerol acyltransferase variant transforms Saccharomyces cerevisiae into an oleaginous yeast
journal, April 2013
- Kamisaka, Yasushi; Kimura, Kazuyoshi; Uemura, Hiroshi
- Applied Microbiology and Biotechnology, Vol. 97, Issue 16