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Title: Xylose utilizing oleaginous yeast

Abstract

Presented herein are oleaginous strains of yeast such as Saccharomyces cerevisiae that have been modified to allow for xylose utilization. Such strains are also modified to allow for higher lipid accumulation utilizing a broad range of sugar monomers such as those released during pretreatment and enzymatic saccharification of lignocellulosic biomass. Methods of producing lipids and ethanol using these yeast strains are also disclosed.

Inventors:
; ; ;
Issue Date:
Research Org.:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632427
Patent Number(s):
10533196
Application Number:
15/282,591
Assignee:
Alliance for Sustainable Energy, LLC (Golden, CO)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC36-08GO28308
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/30/2016
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 09 BIOMASS FUELS

Citation Formats

Knoshaug, Eric P., Zhang, Min, Singh, Arjun, and Guarnieri, Michael T. Xylose utilizing oleaginous yeast. United States: N. p., 2020. Web.
Knoshaug, Eric P., Zhang, Min, Singh, Arjun, & Guarnieri, Michael T. Xylose utilizing oleaginous yeast. United States.
Knoshaug, Eric P., Zhang, Min, Singh, Arjun, and Guarnieri, Michael T. Tue . "Xylose utilizing oleaginous yeast". United States. https://www.osti.gov/servlets/purl/1632427.
@article{osti_1632427,
title = {Xylose utilizing oleaginous yeast},
author = {Knoshaug, Eric P. and Zhang, Min and Singh, Arjun and Guarnieri, Michael T.},
abstractNote = {Presented herein are oleaginous strains of yeast such as Saccharomyces cerevisiae that have been modified to allow for xylose utilization. Such strains are also modified to allow for higher lipid accumulation utilizing a broad range of sugar monomers such as those released during pretreatment and enzymatic saccharification of lignocellulosic biomass. Methods of producing lipids and ethanol using these yeast strains are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {1}
}

Works referenced in this record:

Snf1 Is a Regulator of Lipid Accumulation in Yarrowia lipolytica
journal, September 2013


Anaerobic Xylose Fermentation by Recombinant Saccharomyces cerevisiae Carrying XYL1, XYL2, and XKS1 in Mineral Medium Chemostat Cultures
journal, August 2000


The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response inSaccharomyces cerevisiae
journal, June 2011


Overexpression of the active diacylglycerol acyltransferase variant transforms Saccharomyces cerevisiae into an oleaginous yeast
journal, April 2013