Title: Methods for 2-color radiography with laser-compton X-ray sources

Abstract

High-contrast, subtraction, x-ray images of an object are produced via scanned illumination by a laser-Compton x-ray source. The spectral-angle correlation of the laser-Compton scattering process and a specially designed aperture and/or detector are utilized to produce/record a narrow beam of x-rays whose spectral content consists of an on-axis region of high-energy x-rays surrounded by a region of slightly lower-energy x-rays. The end point energy of the laser-Compton source is set so that the high-energy x-ray region contains photons that are above the k-shell absorption edge (k-edge) of a specific contrast agent or specific material within the object to be imaged while the outer region consists of photons whose energy is below the k-edge of the same contrast agent or specific material. Scanning the illumination and of the object by this beam will simultaneously record and map the above edge and below k-edge absorption response of the object.

Inventors:

Barty, Christopher P. J.

Issue Date:

Tue Dec 17 00:00:00 EST 2019

Research Org.:

Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1600409

Patent Number(s):

10508998

Application Number:

15/319,986

Assignee:

Lawrence Livermore National Security, LLC (Livermore, CA)

Patent Classifications (CPCs):

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

A61B6/06 - Diaphragms {for particular diagnostic applications, e.g. tomography, i.e. not of general applicability
A61B6/405 - {Source units adapted to modify characteristics of the beam during the data acquisition process
A61B6/4241 - {using energy resolving detectors, e.g. photon counting
A61B6/481 - {involving the use of contrast agents}
A61B6/482 - {involving multiple energy imaging}

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N2223/206 - sources operating at different energy levels
G01N2223/408 - display on monitor
G01N2223/423 - multispectral imaging-multiple energy imaging
G01N2223/501 - array
G01N23/087 - using polyenergetic X-rays

G - PHYSICS G21 - NUCLEAR PHYSICS G21K - TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR

G21K1/02 - using diaphragms, collimators
G21K1/043 - {changing time structure of beams by mechanical means, e.g. choppers, spinning filter wheels}

H - ELECTRICITY H05 - ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR H05G - X-RAY TECHNIQUE

H05G2/00 - Apparatus or processes specially adapted for producing X-rays, not involving X-ray tubes, e.g. involving generation of a plasma
H05G2/008 - {involving a beam of energy, e.g. laser or electron beam in the process of exciting the plasma}

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DOE Contract Number:  

AC52-07NA27344

Resource Type:

Patent

Resource Relation:

Patent File Date: 05/07/2015

Country of Publication:

United States

Language:

English

Subject:

62 RADIOLOGY AND NUCLEAR MEDICINE