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Title: Shape memory embolectomy devices and systems

Abstract

An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1600369
Patent Number(s):
10499935
Application Number:
15/094,701
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
DOE Contract Number:  
AC52-07NA27344; R01EB000462
Resource Type:
Patent
Resource Relation:
Patent File Date: 04/08/2016
Country of Publication:
United States
Language:
English

Citation Formats

Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick, and Muschenborn, Andrea D. Shape memory embolectomy devices and systems. United States: N. p., 2019. Web.
Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick, & Muschenborn, Andrea D. Shape memory embolectomy devices and systems. United States.
Szafron, Jason, Maitland, Duncan, Small, IV, Ward, Buckley, Patrick, and Muschenborn, Andrea D. Tue . "Shape memory embolectomy devices and systems". United States. https://www.osti.gov/servlets/purl/1600369.
@article{osti_1600369,
title = {Shape memory embolectomy devices and systems},
author = {Szafron, Jason and Maitland, Duncan and Small, IV, Ward and Buckley, Patrick and Muschenborn, Andrea D.},
abstractNote = {An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {12}
}

Works referenced in this record:

Clot Capture Systems and Associated Methods
patent-application, May 2011


Ultra Low Density Biodegradable Shape Memory Polymer Foams With Tunable Physical Properties
patent-application, May 2014


Design and Characterization of an Endovascular Mechanical Thrombectomy Device1
journal, April 2014


Shape memory polymer actuator and catheter
patent, May 2004


Guide wire extension for shape memory polymer occlusion removal devices
patent, November 2009


Ultra low density and highly crosslinked biocompatible shape memory polyurethane foams
journal, March 2012

  • Singhal, Pooja; Rodriguez, Jennifer N.; Small, Ward
  • Journal of Polymer Science Part B: Polymer Physics, Vol. 50, Issue 10, p. 724-737
  • https://doi.org/10.1002/polb.23056

Shape memory polymer foams for endovascular therapies
patent, May 2015


Clot retrieval system
patent, December 2014


Shape memory polymer medical device
patent, June 2010


Devices and Methods for Removing a Matter from a Body Cavity of a Patient
patent-application, February 2008