Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette

Title: Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette

Abstract

A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule.

Inventors:: Van Dam, R. Michael; Moore, Melissa; Maraglia, Brandon; Thompson, Daniel

Issue Date:: 2019-11-12

Research Org.:: Univ. of California, Oakland, CA (United States); Sofie Biosciences, Inc., Culver City, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1600275

Patent Number(s):: 10,473,668

Application Number:: 15/315,369

Assignee:: The Regents of the University of California (Oakland, CA); Sofie Biosciences, Inc. (Culver City, CA)

DOE Contract Number:: SC0006238

Resource Type:: Patent

Resource Relation:: Patent File Date: 06/05/2015

Country of Publication:: United States

Language:: English

Subject:: 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

Citation Formats


                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, and Thompson, Daniel. Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette.  United States: N. p., 2019. 
        Web.

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                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, & Thompson, Daniel. Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette.  United States.

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                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, and Thompson, Daniel. Tue .  
        "Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette".  United States.  https://www.osti.gov/servlets/purl/1600275.

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@article{osti_1600275,

  title        = {Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette},

  author       = {Van Dam, R. Michael and Moore, Melissa and Maraglia, Brandon and Thompson, Daniel},

  abstractNote = {A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2019},

  month        = {11}

}

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Title: Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette

Abstract

Citation Formats

Digital microfluidic platform for radiochemistry patent, April 2015

Perfusion hyperthermia treatment system and method patent, July 2002

Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography patent, November 2010

Microwave assisted chemical processes patent, October 1999

Microfluidic Radiosynthesis System For Positron Emission Tomography Biomarkers patent-application, February 2009

Microfluidic Platform For Cell Culture And Assay patent-application, June 2011

Digital microfluidic platform for radiochemistry patent, November 2016

Device for synthesis of radiopharmaceutical products patent-application, February 2004

Microfluidic chip capable of synthesizing radioactively labeled molecules on a scale suitable for human imaging with positron emission tomography patent, December 2011

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Modular radiochemistry synthesis system patent, November 2016

System and Method for Processing Chemical Substances, Computer Program for Controlling Such System, and a Corresponding Computer-Readable Storage Medium patent-application, September 2008

Microfluidic handling system patent, October 2016

Disposable world-to-chip interface for digital microfluidics patent, May 2017

Digital microfluidic platform for radiochemistry patent, November 2015

Microfluidic radiosynthesis system for positron emission tomography biomarkers patent, December 2011

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System for purification and analysis of radiochemical products yielded by microfluidic synthesis devices
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