Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette

Title: Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette

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Abstract

A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule.

Inventors:: Van Dam, R. Michael; Moore, Melissa; Maraglia, Brandon; Thompson, Daniel

Issue Date:: 2019-11-12

Research Org.:: Univ. of California, Oakland, CA (United States); Sofie Biosciences, Inc., Culver City, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1600275

Patent Number(s):: 10473668

Application Number:: 15/315,369

Assignee:: The Regents of the University of California (Oakland, CA); Sofie Biosciences, Inc. (Culver City, CA)

Patent Classifications (CPCs):: G - PHYSICS G21 - NUCLEAR PHYSICS G21H - OBTAINING ENERGY FROM RADIOACTIVE SOURCES

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

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G - PHYSICS G21 - NUCLEAR PHYSICS G21H - OBTAINING ENERGY FROM RADIOACTIVE SOURCES
G21H5/02 - as tracers

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B6/542 - {involving control of exposure}

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/60 - involving radioactive labelled substances

G - PHYSICS G21 - NUCLEAR PHYSICS G21F - PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT
G21F5/015 - for storing radioactive sources, e.g. source carriers for irradiation units

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C07B59/00 - Introduction of isotopes of elements into organic compounds {

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B6/037 - {Emission tomography
A61B6/48 - {Diagnostic techniques

G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
G21G1/0005 - {Isotope delivery systems

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DOE Contract Number:: SC0006238

Resource Type:: Patent

Resource Relation:: Patent File Date: 06/05/2015

Country of Publication:: United States

Language:: English

Subject:: 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY

Citation Formats


                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, and Thompson, Daniel. Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette.  United States: N. p., 2019. 
        Web.

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                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, & Thompson, Daniel. Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette.  United States.

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                    Van Dam, R. Michael, Moore, Melissa, Maraglia, Brandon, and Thompson, Daniel. Tue .  
        "Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette".  United States.  https://www.osti.gov/servlets/purl/1600275.

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@article{osti_1600275,

  title        = {Self-shielded, benchtop radio chemistry system with a plurality shielded carriers containing a disposable chip cassette},

  author       = {Van Dam, R. Michael and Moore, Melissa and Maraglia, Brandon and Thompson, Daniel},

  abstractNote = {A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (EWOD) chip to produce a radiolabeled molecule.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2019},

  month        = {11}

}

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