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Title: Microfluidic aspirator and methods of making and using the same

Abstract

Disclosed herein are devices that include a top chamber including at least one port, a bottom chamber including at least one inlet and at least one outlet, wherein the opening of the at least one inlet is smaller than the opening of the at least one outlet, and a membrane located between the top chamber and the bottom chamber, wherein the membrane is fluidly coupled with the top chamber and the bottom chamber. Also disclosed herein are systems including the disclosed devices. The systems include liquid in one or more of the chambers of the device. Methods of using the devices and systems include producing a vacuum by flowing a liquid through the bottom chamber of the system. Due to the difference in size of the inlet and outlet in the bottom chamber, a vacuum is produced in the top chamber.

Inventors:
;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1576337
Patent Number(s):
10,408,821
Application Number:
15/488,245
Assignee:
Triad National Security, LLC (Los Alamos, NM)
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 2017 Apr 14
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

Citation Formats

Nath, Pulak, and Huang, Jen-Huang. Microfluidic aspirator and methods of making and using the same. United States: N. p., 2019. Web.
Nath, Pulak, & Huang, Jen-Huang. Microfluidic aspirator and methods of making and using the same. United States.
Nath, Pulak, and Huang, Jen-Huang. Tue . "Microfluidic aspirator and methods of making and using the same". United States. https://www.osti.gov/servlets/purl/1576337.
@article{osti_1576337,
title = {Microfluidic aspirator and methods of making and using the same},
author = {Nath, Pulak and Huang, Jen-Huang},
abstractNote = {Disclosed herein are devices that include a top chamber including at least one port, a bottom chamber including at least one inlet and at least one outlet, wherein the opening of the at least one inlet is smaller than the opening of the at least one outlet, and a membrane located between the top chamber and the bottom chamber, wherein the membrane is fluidly coupled with the top chamber and the bottom chamber. Also disclosed herein are systems including the disclosed devices. The systems include liquid in one or more of the chambers of the device. Methods of using the devices and systems include producing a vacuum by flowing a liquid through the bottom chamber of the system. Due to the difference in size of the inlet and outlet in the bottom chamber, a vacuum is produced in the top chamber.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {9}
}

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Works referenced in this record:

Device for maintaining and growing human stem and/or hematopoietics cells
patent, October 1995