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Title: Thermoplastic elastomer hydrogels

Abstract

Provided herein is a block copolymer hydrogel, comprising a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight. The block copolymer hydrogel has a fatigue resistance to at least 500,000 compression cycles. Also provided are methods for forming the hydrogel.

Inventors:
; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Colorado State Univ., Fort Collins, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1576246
Patent Number(s):
10428185
Assignee:
Colorado State University Research Foundation (Fort Collins, CO); The Regents of the University of Colorado (Denver, CO)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
DOE Contract Number:  
AR0000098; AR069826; CBET1160026; DMR0645781
Resource Type:
Patent
Resource Relation:
Patent File Date: 2016 Dec 05
Country of Publication:
United States
Language:
English

Citation Formats

Bailey, Travis S., Guo, Chen, Lewis, Jackson T., Fischenich, Kristine, Donahue, Tammy Haut, Wijayasekara, Dilanji, Cowan, Matthew G., Gin, Douglas L., and Noble, Richard D. Thermoplastic elastomer hydrogels. United States: N. p., 2019. Web.
Bailey, Travis S., Guo, Chen, Lewis, Jackson T., Fischenich, Kristine, Donahue, Tammy Haut, Wijayasekara, Dilanji, Cowan, Matthew G., Gin, Douglas L., & Noble, Richard D. Thermoplastic elastomer hydrogels. United States.
Bailey, Travis S., Guo, Chen, Lewis, Jackson T., Fischenich, Kristine, Donahue, Tammy Haut, Wijayasekara, Dilanji, Cowan, Matthew G., Gin, Douglas L., and Noble, Richard D. Tue . "Thermoplastic elastomer hydrogels". United States. https://www.osti.gov/servlets/purl/1576246.
@article{osti_1576246,
title = {Thermoplastic elastomer hydrogels},
author = {Bailey, Travis S. and Guo, Chen and Lewis, Jackson T. and Fischenich, Kristine and Donahue, Tammy Haut and Wijayasekara, Dilanji and Cowan, Matthew G. and Gin, Douglas L. and Noble, Richard D.},
abstractNote = {Provided herein is a block copolymer hydrogel, comprising a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO—SOS by weight. The block copolymer hydrogel has a fatigue resistance to at least 500,000 compression cycles. Also provided are methods for forming the hydrogel.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {10}
}

Works referenced in this record:

Injection Molding of Living Tissues
patent-application, October 2002


Hydrogels Having Enhanced Elasticity and Mechanical Strength Properties
patent-application, December 2003


Implantable or Insertable Medical Devices for Controlled Delivery of a Therapeutic Agent
patent-application, December 2003


Guided Development and Support of Hydrogel-Cell Compositions
patent-application, May 2004


Ion Gels and Electronic Devices Utilizing Ion Gels
patent-application, August 2008


Solid Polymer Electrolytes Based on Triblock Copolymers, Especially Polystyrene-Poly(Oxyethylene)-Polystyrene
patent-application, September 2010


Cucurbituril-Based Hydrogels
patent-application, April 2015