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Title: Metabolic flux measurement, imaging and microscopy

Abstract

Provided herein are methods for measuring molecular flux rates of molecules of interest in a tissue sample in spatially-organized manner and generating output (e.g., an image, a heat map, a contour map, a table or a database) representing the molecular flux rates of each spatially-defined location of the sample. Provided herein are also the output, as well as systems and computer-readable medium with computer-executable instructions for determining molecular flux rates of molecules of interest in the sample.

Inventors:
; ; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568748
Patent Number(s):
10386371
Application Number:
14/343,334
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16B - BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
DOE Contract Number:  
AC02-05CH11231; CA112970
Resource Type:
Patent
Resource Relation:
Patent File Date: 09/07/2012
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Bowen, Benjamin P., Louie, Katherine B., Northen, Trent R., and Hellerstein, Marc K. Metabolic flux measurement, imaging and microscopy. United States: N. p., 2019. Web.
Bowen, Benjamin P., Louie, Katherine B., Northen, Trent R., & Hellerstein, Marc K. Metabolic flux measurement, imaging and microscopy. United States.
Bowen, Benjamin P., Louie, Katherine B., Northen, Trent R., and Hellerstein, Marc K. Tue . "Metabolic flux measurement, imaging and microscopy". United States. https://www.osti.gov/servlets/purl/1568748.
@article{osti_1568748,
title = {Metabolic flux measurement, imaging and microscopy},
author = {Bowen, Benjamin P. and Louie, Katherine B. and Northen, Trent R. and Hellerstein, Marc K.},
abstractNote = {Provided herein are methods for measuring molecular flux rates of molecules of interest in a tissue sample in spatially-organized manner and generating output (e.g., an image, a heat map, a contour map, a table or a database) representing the molecular flux rates of each spatially-defined location of the sample. Provided herein are also the output, as well as systems and computer-readable medium with computer-executable instructions for determining molecular flux rates of molecules of interest in the sample.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {8}
}

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