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Title: Optimized thionin protects plants against bacterial infections

Abstract

Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin. Genetically altered plants and their progeny expressing a polynucleotide encoding optimized pro-thionin or optimized thionin resist diseases caused by bacteria.

Inventors:
; ;
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568711
Patent Number(s):
10378024
Application Number:
15/637,660
Assignee:
The United States of America as represented by the Secretary of Agriculture (Washington, DC)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 06/29/2017
Country of Publication:
United States
Language:
English

Citation Formats

Stover, Eddie W., Gupta, Goutam, and Hao, Guixia. Optimized thionin protects plants against bacterial infections. United States: N. p., 2019. Web.
Stover, Eddie W., Gupta, Goutam, & Hao, Guixia. Optimized thionin protects plants against bacterial infections. United States.
Stover, Eddie W., Gupta, Goutam, and Hao, Guixia. Tue . "Optimized thionin protects plants against bacterial infections". United States. https://www.osti.gov/servlets/purl/1568711.
@article{osti_1568711,
title = {Optimized thionin protects plants against bacterial infections},
author = {Stover, Eddie W. and Gupta, Goutam and Hao, Guixia},
abstractNote = {Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin. Genetically altered plants and their progeny expressing a polynucleotide encoding optimized pro-thionin or optimized thionin resist diseases caused by bacteria.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {8}
}