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Title: Pet imaging of zinc transport

Abstract

A method for producing a solution including a positron emitting zinc cation of .sup.63Zn, and the method comprises bombarding a solution target including .sup.63Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to beta-amyloid in the patient, and acquiring an image to detect the presence or absence of beta-amyloid in the patient.

Inventors:
; ; ;
Issue Date:
Research Org.:
Mayo Foundation for Medical Education and Research, Rochester, MN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568289
Patent Number(s):
10,279,054
Application Number:
14/902,744
Assignee:
Mayo Foundation for Medical Education and Research (Rochester, MN)
DOE Contract Number:  
SC0008947
Resource Type:
Patent
Resource Relation:
Patent File Date: 07/09/2014
Country of Publication:
United States
Language:
English

Citation Formats

Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, and Lowe, Val J. Pet imaging of zinc transport. United States: N. p., 2019. Web.
Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, & Lowe, Val J. Pet imaging of zinc transport. United States.
Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, and Lowe, Val J. Tue . "Pet imaging of zinc transport". United States. https://www.osti.gov/servlets/purl/1568289.
@article{osti_1568289,
title = {Pet imaging of zinc transport},
author = {Degrado, Timothy R. and Pandey, Mukesh K. and Engelbrecht, Hendrik Petrus and Lowe, Val J.},
abstractNote = {A method for producing a solution including a positron emitting zinc cation of .sup.63Zn, and the method comprises bombarding a solution target including .sup.63Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to beta-amyloid in the patient, and acquiring an image to detect the presence or absence of beta-amyloid in the patient.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {5}
}

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