Linear peptides that mimic structural epitopes for antibody assays
Abstract
A method including identifying one or more structures in adjacent sequences of one or more proteins that can be mimicked by a peptide; and assembling a peptide that mimics the one or more secondary structures. A method including assembling epitopes of linked pairs of discontiguous peptide subsequences that mimic one or more structures in sequences of a protein; and assaying antibodies against the epitopes.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568236
- Patent Number(s):
- 10267788
- Application Number:
- 14/159,308
- Assignee:
- National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 01/20/2014
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Schoeniger, Joseph S., and Anderson, Peter. Linear peptides that mimic structural epitopes for antibody assays. United States: N. p., 2019.
Web.
Schoeniger, Joseph S., & Anderson, Peter. Linear peptides that mimic structural epitopes for antibody assays. United States.
Schoeniger, Joseph S., and Anderson, Peter. Tue .
"Linear peptides that mimic structural epitopes for antibody assays". United States. https://www.osti.gov/servlets/purl/1568236.
@article{osti_1568236,
title = {Linear peptides that mimic structural epitopes for antibody assays},
author = {Schoeniger, Joseph S. and Anderson, Peter},
abstractNote = {A method including identifying one or more structures in adjacent sequences of one or more proteins that can be mimicked by a peptide; and assembling a peptide that mimics the one or more secondary structures. A method including assembling epitopes of linked pairs of discontiguous peptide subsequences that mimic one or more structures in sequences of a protein; and assaying antibodies against the epitopes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {4}
}
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