Zero voltage mass spectrometry probes and systems
Abstract
The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.
- Inventors:
- Issue Date:
- Research Org.:
- Purdue Univ., West Lafayette, IN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568185
- Patent Number(s):
- 10256085
- Application Number:
- 15/697,560
- Assignee:
- Purdue Research Foundation (West Lafayette, IN)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- FG02-06ER15807
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 09/07/2017
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Cooks, Robert Graham, Wleklinski, Michael Stanley, Bag, Soumabha, and Li, Yafeng. Zero voltage mass spectrometry probes and systems. United States: N. p., 2019.
Web.
Cooks, Robert Graham, Wleklinski, Michael Stanley, Bag, Soumabha, & Li, Yafeng. Zero voltage mass spectrometry probes and systems. United States.
Cooks, Robert Graham, Wleklinski, Michael Stanley, Bag, Soumabha, and Li, Yafeng. Tue .
"Zero voltage mass spectrometry probes and systems". United States. https://www.osti.gov/servlets/purl/1568185.
@article{osti_1568185,
title = {Zero voltage mass spectrometry probes and systems},
author = {Cooks, Robert Graham and Wleklinski, Michael Stanley and Bag, Soumabha and Li, Yafeng},
abstractNote = {The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {4}
}
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Works referenced in this record:
Process for the detection and quantitation of corrosion and scale inhibitors in produced well fluids
patent, October 1992
- Buck, Erwin; Sudbury, John
- US Patent Document 5,152,177
On-line/at-line monitoring of residual chemical by surface enhanced Raman spectroscopy
patent, October 2012
- Sardashti, Maziar; Blumer, David J.; McEnroe, Frank J.
- US Patent Document 8,294,892
Analyzing Apparatus
patent-application, November 2013
- Imai, Akira; Sato, Tomoyoshi
- US Patent Document 13/881915; 20130299694
Apparatus for the removal of an edge polymer from a substrate and methods therefor
patent, January 2010
- Yoon, Hyungsuk Alexander; Kim, Yunsang; Ryder, Jason A.
- US Patent Document 7,651,585
Method and system for desorption atmospheric pressure chemical ionization
patent-application, December 2009
- Cooks, Robert G.; Gologan, Bogdan; Takats, Zoltan
- US Patent Document 12/481501; 20090309020
Fourtier transform quadrupole mass spectrometer and method
patent, July 1988
- Syka, John; Fies, Jr., William J.
- US Patent Document 4,755,670
System for performing blood coagulation assays and measuring blood clotting times
patent-application, September 2003
- Mpock, Emmanuel C.; Clawson, Ben; Murphy, Sean P.
- US Patent Document 10/397088; 20030180824
Porous electrospray emitter
patent-application, December 2004
- Granger, Michael C.; Van Berkel, Gary J.
- US Patent Document 10/849098; 20040245457
Data correction, normalization and validation for quantitative high-throughput metabolomic profiling
patent-application, September 2006
- Kanani, Harin; Klapa, Maria I.
- US Patent Document 11/362717; 20060200316
Ion Generation Using Wetted Porous Material
patent-application, May 2013
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 13/727173; 20130112867
Apparatus and methods for continuous beam fourier transform mass spectrometry
patent, September 2002
- McLuckey, Scott A.; Goeringer, Douglas E.
- US Patent Document 6,452,168
Ion generation using wetted porous material
patent, August 2014
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 8,816,275
Zero voltage mass spectrometry probes and systems
patent, October 2017
- Cooks, Robert Graham; Wleklinski, Michael Stanley; Bag, Soumabha
- US Patent Document 9,786,478
Ionization Analysis Method and Apparatus
patent-application, May 2011
- Hiraoka, Kenzo; Chen, Lee Chuin
- US Patent Document 13/001330; 20110108726
Mass spectrometry analysis of microorganisms in samples
patent, April 2014
- Cooks, Robert Graham; Hamid, Ahmed Mohamed; Jarmusch, Alan Keith
- US Patent Document 8,704,167
Systems for Detecting Analytes
patent-application, May 2002
- Naylor, Stephen; O'Brien, John F.; Bergen, III, H. Robert
- US Patent Document 09/391432; 20020055184
Chemical ionization reaction or proton transfer reaction mass spectrometry
patent, December 2012
- Robinson, Timothy Roger; Attwood, Mark James; Chen, Xing
- US Patent Document 8,334,505
Assembly for collecting samples for purposes of identification or analysis and method of use
patent-application, February 2007
- Thompson, Cyril V.; Smith, Rob R.
- US Patent Document 11/194095; 20070025881
Methods for solid phase nanoextraction and desorption
patent-application, March 2002
- Singh, Rajendra; Cromer, Remy; Natan, Michael J.
- US Patent Document 09/920440; 20020034827
Ionization Emitter, Ionization Apparatus, and Method for Manufacturing Ionization Emitter
patent-application, March 2010
- Horiike, Shigeyoshi; Nakanishi, Hiroaki
- US Patent Document 12/523725; 20100059689
Biomarkers Useful for Diagnosing Prostate Cancer, and Methods Thereof
patent-application, May 2009
- Ritchie, Shawn; Bingham, Erin
- US Patent Document 12/294215; 20090127454
Low-temperature, converging, reactive gas source and method of use
patent, December 2012
- Babayan, Steve E.; Hicks, Robert F.
- US Patent Document 8,328,982
Microfabricated ion trap array
patent, December 2006
- Blain, Matthew G.; Fleming, James G.
- US Patent Document 7,154,088
Integrated monolithic microfabricated electrospray and liquid chromatography system and method
patent-application, September 2002
- Moon, James E.; Davis, Timothy J.; Galvin, Gregory J.
- US Patent Document 09/970717; 20020123153
Method and system for desorption atmospheric pressure chemical ionization
patent, June 2009
- Cooks, Robert Graham; Gologan, Bogdan; Takts, Zoltn
- US Patent Document 7,544,933
Discontinuous atmospheric pressure interface
patent, November 2012
- Ouyang, Zheng; Gao, Liang; Cooks, Robert Graham
- US Patent Document 8,304,718
Time-of-flight bacteria analyser using metastable source ionization
patent, September 2003
- Bertrand, Michel J.; Peraldi, Olivier
- US Patent Document 6,627,881
Method and apparatus for an electrospray needle for use in mass spectrometry
patent-application, November 2005
- Park, Melvin A.
- US Patent Document 10/371152; 20050247870
Method and Apparatus for a Porous Metal Electrospray Emitter
patent-application, September 2011
- Lozano, Paulo; Legge, Robert Scott
- US Patent Document 12/990923; 20110210265
Analysis of Hydrocarbon Liquid and Solid Samples
patent-application, June 2014
- Wu, Chunping; Walters, Clifford C.; Qian, Kuangnan
- US Patent Document 14/071712; 20140165701
Interfacing Low-Flow Separation Techniques
patent-application, January 2010
- Moini, Mehdi
- US Patent Document 12/501600; 20100001181
Loop certification and measurement for ADSL
patent, November 2002
- Schneider, Allan; Hofman, Frederick G.; Sylvester, James E.
- US Patent Document 6,477,238
Discontinuous Atmospheric Pressure Interface
patent-application, December 2010
- Ouyang, Zheng; Gao, Liang; Cooks, Robert Graham
- US Patent Document 12/622776; 20100301209
Low temperature plasma probe and methods of use thereof
patent, August 2013
- Charipar, Nicholas Alan; Harper, Jason David; Ouyang, Zheng
- US Patent Document 8,519,354
Remote testing of a communications line
patent, March 2006
- Wooding, Jeffrey
- US Patent Document 7,010,096
Method and system for desorption electrospray ionization
patent, February 2008
- Takts, Zoltn; Gologan, Bogdan; Wiseman, Justin M.
- US Patent Document 7,335,897
Generation of Model-of-Composition of Petroleum by High Resolution Mass Spectrometry and Associated Analytics
patent-application, June 2012
- Qian, Kuangnan; Edwards, Kathleen E.; Mennito, Anthony S.
- US Patent Document 13/167816; 20120153139
Systems and methods for sample analysis
patent, October 2015
- Cooks, Robert Graham; Li, Guangtao; Li, Xin
- US Patent Document 9,165,752
Ion Generation Using Wetted Porous Material
patent-application, May 2013
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 13/727167; 20130112866
Adsorption, detection and identification of components of ambient air with desorption/ionization on silicon mass spectrometry (DIOS-MS)
patent, July 2009
- Finch, Jeffrey W.; Stumpf, Chris L.; Compton, Bruce J.
- US Patent Document 7,564,027
Corrosion prevention with compositions prepared from organic fatty amines and nitrogen-containing aromatic heterocyclic compounds
patent, September 1990
- Treybig, Duane S.; Martinez, Robert G.
- US Patent Document 4,957,640
System for the online measurement of volatile and semi-volatile compounds and use thereof
patent, April 2011
- Krogh, Erik Thomas; Gill, Christopher G.
- US Patent Document 7,930,924
Methods and Devices for Concentration and Fractionation of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry (MS)
patent-application, March 2009
- Hafeman, Dean G.; Harkins, IV, James B.; Norris, Jeremy L.
- US Patent Document 12/136021; 20090071834
Electrospray emitter
patent-application, July 2003
- Nilsson, Steffan; Wetterhall, Magnus; Berquist, Jonas
- US Patent Document 10/297718; 20030141392
Device including a dissolvable structure for flow control
patent-application, May 2006
- Banerjee, Debjyoti; Faulstich, Konrad; Lau, Aldrich N. K.
- US Patent Document 11/252821; 20060093528
Multiple sampling device and method for investigating biological systems
patent, August 2007
- Pawliszyn, Janusz B.; Lord, Heather L.; Musteata, Marcel
- US Patent Document 7,259,019
Ion Generation Using Wetted Porous Material
patent-application, May 2012
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 13/265110; 20120119079
Ion generation using wetted porous material
patent, October 2014
- Cooks, Robert Graham; Hamid, Ahmed Mohamed; Jarmusch, Alan Keith
- US Patent Document 8,859,986
Method of photometric in vitro determination of the content of an analyte in a sample of whole blood
patent, February 1994
- Lundsgaard, Finn C.; Jensen, Niels-Henrik; Andersen, Willy Lindegaard
- US Patent Document 5,288,646
Sample collection apparatus
patent, October 2011
- McCash, Elaine Marie; Murray, Nicol John
- US Patent Document 8,030,088
Method of synthesis and delivery of complex pharmaceuticals, chemical substances and polymers through the process of electrospraying, electrospinning or extrusion utilizing holey fibers
patent-application, June 2005
- Dziekan, Michael E.; Bango, Joseph J.; Fenn, John B.
- US Patent Document 11/000723; 20050117864
Devices and methods for reduction of NOx emissions from lean burn engines
patent-application, July 2007
- Dalla Betta, Ralph A.; Cizeron, Joel; Sheridan, David R.
- US Patent Document 11/715854; 20070151232
Ion source for a mass spectrometer
patent, November 1992
- Chapman, John R.; Jones, David S.
- US Patent Document 5,160,841
Apparatus and method for thermal assisted desorption ionization systems
patent, June 2014
- Krechmer, Jordan; Musselman, Brian
- US Patent Document 8,754,365
Mass analyzing apparatus
patent, February 2010
- Lin, Che-hsin; Shiea, Jentaie; Hsu, Wei-Jen
- US Patent Document 7,667,197
Nebulizer with plasma source
patent, February 2006
- Ahern, Michael; Kingston, Jr., Howard M.
- US Patent Document 7,005,635
Apparatus for holding solids for use with surface ionization technology
patent, May 2010
- Musselman, Brian
- US Patent Document 7,714,281
Systems and methods for transfer of ions for analysis
patent, April 2013
- Musselman, Brian
- US Patent Document 8,421,005
Method and system for desorption atmospheric pressure chemical ionization
patent-application, August 2007
- Cooks, Robert G.; Gologan, Bogdan; Takats, Zoltan
- US Patent Document 11/653569; 20070187589
Electrospray Ionization Mass Spectrometry Methodology
patent-application, September 2010
- Marshall, Alan G.; Juyal, Priyanka; Rodgers, Ryan P.
- US Patent Document 12/700992; 20100230587
Mass Spectrometer
patent-application, November 2008
- Takeuchi, Sadao; Waki, Hiroaki; Ding, Li
- US Patent Document 12/093862; 20080283742
Use of benzazoles as corrosion inhibitors
patent, November 1980
- Redmore, Derek; Outlaw, Benjamin T.
- US Patent Document 4,235,838
Quantification of analytes using internal standards
patent-application, May 2005
- Gentle, Thomas; Moore, Richard; Winegar, Thomas
- US Patent Document 10/945891; 20050112635
Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions
patent, May 2007
- Schultz, J. Albert; Raznikov, Valeri V.; Egan, II, Thomas F.
- US Patent Document 7,223,969
Plasma treatment apparatus and plasma generation method using the apparatus
patent, October 2002
- Taguchi, Noriyuki; Sawada, Yasushi; Yamazaki, Keiichi
- US Patent Document 6,465,964
Method and device for evaluating the state of organisms and natural products and for analyzing a gaseous mixture comprising main constituents and secondary constituents
patent, January 2006
- Villinger, Johannes; Federer, Werner
- US Patent Document 6,982,416
Telecommunications interruption and disconnection apparatus and methods
patent, January 2007
- Hoffman, Lawrence Andrew
- US Patent Document 7,171,193
Ion Focusing and Detection in a Miniature Linear Ion Trap for Mass Spectrometry
patent-application, January 2010
- Dobson, Gareth S.; Enke, Christie G.
- US Patent Document 11/753455; 20100019143
On-line and off-line coupling of EC with DESI-MS
patent, December 2012
- Chen, Hao; Li, Jiwen; Miao, Zhixin
- US Patent Document 8,330,119
Apparatus, System and Method for Purifying Nucleic Acids
patent-application, May 2011
- Ewing, Kenneth J.; Dickinson, Danielle N.; Henderson, Douglas B.
- US Patent Document 12/967451; 20110108724
Mechanical Holder for Surface Analysis
patent-application, January 2012
- Eikel, Daniel; Henion, John D.; Alpha, Christopher
- US Patent Document 13/100383; 20120018629
Nanostructure-Initiator Mass Spectrometry
patent-application, June 2008
- Northen, Trent; Siuzdak, Gary; Nordstrom, Anders
- US Patent Document 11/852863; 20080128608
Mass Spectrometer And Mass Analyzing Method
patent-application, December 2012
- Kumano, Shun; Sugiyama, Masuyuki; Hashimoto, Yuichiro
- US Patent Application 13/527627; 20120326022
Microspray Liquid-Liquid Extractive Ionization Device
patent-application, July 2008
- Chen, Huanwen; Chen, Hao; Venter, Andre
- US Patent Document 11/751718; 20080179511
Solid-Phase Extraction (SPE) Tips and Methods of Use
patent-application, June 2011
- Henion, John D.; Kurz, Thomas
- US Patent Document 12/960037; 20110133077
Method and apparatus of liquid sample-desorption electrospray ionization-mass specrometry (LS-DESI-MS)
patent, March 2011
- Chen, Hao; Miao, Zhixin
- US Patent Document 7,915,579
Laser desorption - electrospray ion (ESI) source for mass spectrometers
patent-application, November 2008
- Kovtoun, Viatcheslav V.
- US Patent Document 11/799910; 20080272294
Self-blunting needle assembly and device including the same
patent, May 1989
- Sahi, Carl R.; Phillips, Richard R.; Fudge, Chester M.
- US Patent Document 4,828,547
Liquid cheromatography/mass spectrometry apparatus
patent-application, June 2006
- Matsui, Mayumi; Waki, Hiroaki
- US Patent Document 11/287289; 20060118713
Ion generation using modified wetted porous materials
patent, November 2014
- Cooks, Robert Graham; Ouyang, Zheng; Zhang, Zhiping
- US Patent Document 8,895,918
Test tray, kit and methods for bodily fluid testing for newborn screening by tandem mass spectrometry
patent-application, October 2003
- Ostrup, Jan
- US Patent Document 10/458831; 20030199102
High Throughput Testing for Presence of Microorganisms in a Biological Sample
patent-application, December 2009
- Semikhodskii, Andrei; Green, Simon
- US Patent Document 12/161829; 20090306230
Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions
patent, January 2006
- Schultz, J. Albert; Raznikov, Valeri V.; Egan, II, Thomas F.
- US Patent Document 6,992,284
Scanned Source Oriented Nanofiber Formation
patent-application, November 2009
- Craighead, Harold G.; Kameoka, Jun
- US Patent Document 12/470327; 20090280300
Systems and methods for sample analysis
patent, January 2015
- Cooks, Robert Graham; Li, Guangtao; Li, Xin
- US Patent Document 8,932,875
Apparatus and method for dispensing a sample
patent-application, April 2004
- Rossier, Joel Stephane; Reymond, Frederic; Girault, Hubert Hugues
- US Patent Document 10/467973; 20040075050
Combined electrophoresis-electrospray interface and method
patent, December 1989
- Smith, Richard P.; Udseth, Harold R.; Olivares, Jose A.
- US Patent Document 4,885,076
Coupling of Liquid Chromatography with Mass Spectrometry by Liquid Sample Desorption Electrospray Ionization (DESI)
patent-application, January 2013
- Chen, Hao; Zhang, Yun; Yuan, Zongqian
- US Patent Document 13/553145; 20130023005
Methods and apparatus for porous membrane electrospray and multiplexed coupling of microfluidic systems with mass spectrometry
patent-application, August 2006
- DeVoe, Donald L.; Wang, Yingxin; Lee, Cheng S.
- US Patent Document 11/242842; 20060192107
Mass analyzer system for the direct determination of organic compounds in PPB and high PPT concentrations in the gas phase
patent, July 1988
- Korte, Friedhelm; Parlar, Ahmet H.; Coulston, Frederick
- US Patent Document 4,757,198
Low temperature plasma probe and methods of use thereof
patent, July 2014
- Ouyang, Zheng; Harper, Jason David; Charipar, Nicholas Alan
- US Patent Document 8,772,710
Low temperature plasma enhanced CVD ceramic coating process for metal, alloy and ceramic materials
patent, November 2002
- Liu, Shengzhong Frank
- US Patent Document 6,482,476
Device for quantitative analysis of a drug or metabolite profile
patent-application, January 2007
- Ramsay, Steven Lewis; Guggenbichler, Wolfgang; Weinberger, Klaus Michael
- US Patent Document 11/476657; 20070003965
Apparatus and method for ion production enhancement
patent, November 2006
- Truche, Jean-Luc; Bai, Jian; Joyce, Timothy H.
- US Patent Document 7,135,689
Method and system for desorption atmospheric pressure chemical ionization
patent, December 2011
- Cooks, Robert Graham; Gologan, Bogdan; Takts, Zoltn
- US Patent Document 8,076,639
Method for Inhibiting Corrosion
patent-application, August 2011
- Mackenzie, Cameron; Magdalenic, Vjera; Moussavi, Artin
- US Patent Document 13/003946; 20110193027
Fingerprinting of Complex Hydrocarbon Containing Mixtures
patent-application, September 2008
- Eide, Ingvar; Zahlsen, Kolbjorn
- US Patent Document 10/587805; 20080210856
Device for use in chemical test procedures
patent, August 1992
- Shanks, Ian; Smith, Alan M.; Nylander, Claes I.
- US Patent Document 5,141,868
Ion generation using wetted porous material
patent, April 2014
- Cooks, Robert Graham; Hamid, Ahmed Mohamed; Jarmusch, Alan Keith
- US Patent Document 8,710,437
Analyzing a Metabolite Level in a Sample
patent-application, October 2013
- Cooks, Robert Graham; Kerian, Kevin Scott; Jarmusch, Alan Keith
- US Patent Document 13/909619; 20130273560
Method and apparatus for an electrospray needle for use in mass spectrometry
patent-application, January 2004
- Park, Melvin A.
- US Patent Document 10/371152; 20040011954
Multidimensional mass spectrometry of serum and cellular lipids directly from biologic extracts
patent, March 2009
- Gross, Richard W.; Han, Xianlin
- US Patent Document 7,510,880
Surface charging to improve wettability
patent, August 1998
- Murokh, Igor Y.; Kerner, Alex Aron
- US Patent Document 5,798,146
Micro-devices and analytical procedures for investigation of biological systems
patent, June 2008
- Pawliszyn, Janusz B.
- US Patent Document 7,384,794
Methods and systems for quantification of peptides and other analytes
patent-application, April 2009
- Grant, Russell Philip; Wagner, Andrew Dennis
- US Patent Document 12/156391; 20090090856
Electrospray Device And A Method of Electrospraying
patent-application, June 2009
- Stark, John P. W.; Paine, Mark D.; Alexander, Matthew S.
- US Patent Document 12/096253; 20090152371
Membrane for holding samples for use with surface ionization technology
patent, July 2013
- Musselman, Brian
- US Patent Document 8,481,922
Method and apparatus for electrospray ionization
patent, October 2001
- Fenn, Jr., John B.
- US Patent Document 6,297,499
Device and Method for Introducing Multiple Liquid Samples at Atmospheric Pressure for Mass Spectrometry
patent-application, April 2008
- Giardina, Matthew
- US Patent Document 11/867142; 20080083873
Ion generation using wetted porous material
patent, October 2014
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 8,859,959
Mercaptoalcohol corrosion inhibitors
patent, November 2003
- Ahn, Young Soo; Jovancicevic, Vladimir
- US Patent Document 6,645,399
Ion generation using wetted porous material
patent, October 2014
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 8,859,958
Gas sampler for molten metal and method
patent, April 2001
- Junker, Thomas W.; Falk, Richard A.
- US Patent Document 6,216,526
Ion generation using wetted porous material
patent, October 2014
- Ouyang, Zheng; Wang, He; Manicke, Nicholas E.
- US Patent Document 8,859,956
Biological measurement system
patent, June 2008
- McCash, Elaine Marie; Wheeler, Gavin Vashon; Colby, Edward
- US Patent Document 7,384,793