Title: Methods for elevating fat/oil content in plants

Abstract

In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algae cells, plant tissues, or whole plants by genetically modifying the plant or algae to express a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian origin. Also provided are genetically-modified plant or algae cells, plant tissues, or whole plants with elevated cellular lipid content, expressing a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian (e.g. human) origin.

Inventors:

Puri, Vishwajeet; Chapman, Kent; James, Christopher

Issue Date:

2019-04-09

Research Org.:

Boston Medical Center Corp., Boston, MA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1568167

Patent Number(s):

10253325

Application Number:

13/830,012

Assignee:

Boston Medical Center Corporation (Boston, MA)

Patent Classifications (CPCs):

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

C07K14/415 - from plants

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N15/8247 - {involving modified lipid metabolism, e.g. seed oil composition}

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P7/6463 - {obtained from glyceride producing microorganisms, e.g. single cell oil}

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DOE Contract Number:  

SC0000797

Resource Type:

Patent

Resource Relation:

Patent File Date: 03/14/2013

Country of Publication:

United States

Language:

English

Subject:

59 BASIC BIOLOGICAL SCIENCES