Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry
Abstract
Disclosed herein are methods, compositions and systems for analyzing and detecting enzyme activity. For examples, methods, compositions and systems for parallel detection and analysis of enzymatic activities of enzymes in complex biological mixtures are provided.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568111
- Patent Number(s):
- 10240180
- Application Number:
- 13/363,695
- Assignee:
- The Regents of the University of California (Oakland, CA); National Technology & Engineering Solutions of Sandia, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 02/01/2012
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 77 NANOSCIENCE AND NANOTECHNOLOGY
Citation Formats
Northen, Trent R., Reindl, Wolfgang E., Deng, Kai, Singh, Seema, Singh, Anup K., and Cheng, Xiaoliang. Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry. United States: N. p., 2019.
Web.
Northen, Trent R., Reindl, Wolfgang E., Deng, Kai, Singh, Seema, Singh, Anup K., & Cheng, Xiaoliang. Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry. United States.
Northen, Trent R., Reindl, Wolfgang E., Deng, Kai, Singh, Seema, Singh, Anup K., and Cheng, Xiaoliang. Tue .
"Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry". United States. https://www.osti.gov/servlets/purl/1568111.
@article{osti_1568111,
title = {Multiplexed screening of enzyme activities using nanostructure-initiator mass spectrometry},
author = {Northen, Trent R. and Reindl, Wolfgang E. and Deng, Kai and Singh, Seema and Singh, Anup K. and Cheng, Xiaoliang},
abstractNote = {Disclosed herein are methods, compositions and systems for analyzing and detecting enzyme activity. For examples, methods, compositions and systems for parallel detection and analysis of enzymatic activities of enzymes in complex biological mixtures are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {3}
}
Works referenced in this record:
Rapid Discovery and Screening of Enzyme Activity Using Mass Spectrometry
patent-application, November 2015
- Northen, Trent R.; Deng, Kai; De Rond, Tristan P.
- US Patent Application 14/651546; 20150330992
Nanostructure-Initiator Mass Spectrometry
patent-application, June 2008
- Northen, Trent; Siuzdak, Gary; Nordstrom, Anders
- US Patent Document 11/852863; 20080128608
Multiplexed Screening of Enzyme Activities Using Nanostructure-initiator Mass Spectrometry
patent-application, September 2012
- Northen, Trent R.; Reindl, Wolfgang E.; Deng, Kai
- US Patent Application 13/363695; 20120225797