Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap

Title: Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap

Abstract

Disclosed herein are methods of immobilizing a particle which comprise focusing the flow of a sample fluid containing the particle into a virtual channel which flows towards an unoccupied hydrodynamic trap in a microfluidic channel such that the particle flows into the hydrodynamic trap and becomes immobilized therein. Also disclosed are microfluidic devices which comprise at least one microchannel having at least one hydrodynamic trap, at least one focusing fluid inlet, said focusing fluid inlet is upstream of the hydrodynamic trap such that a focusing fluid introduced therein results in a virtual channel of a sample fluid when present which preferentially flows toward the hydrodynamic trap.

Inventors:: Perroud, Thomas D.; Patel, Kamlesh D.

Issue Date:: 2014-08-26

Research Org.:: Sandia Corp., Albuquerque, NM (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1532114

Patent Number(s):: 8,815,177

Application Number:: 12/812,974

Assignee:: Sandia Corporation (Albuquerque, NM)

Resource Type:: Patent

Resource Relation:: Patent File Date: 2009-01-21

Country of Publication:: United States

Language:: English

Subject:: 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS

Citation Formats


                    Perroud, Thomas D., and Patel, Kamlesh D. Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap.  United States: N. p., 2014. 
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                    Perroud, Thomas D., & Patel, Kamlesh D. Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap.  United States.

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                    Perroud, Thomas D., and Patel, Kamlesh D. Tue .  
        "Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap".  United States.  https://www.osti.gov/servlets/purl/1532114.

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@article{osti_1532114,

  title        = {Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap},

  author       = {Perroud, Thomas D. and Patel, Kamlesh D.},

  abstractNote = {Disclosed herein are methods of immobilizing a particle which comprise focusing the flow of a sample fluid containing the particle into a virtual channel which flows towards an unoccupied hydrodynamic trap in a microfluidic channel such that the particle flows into the hydrodynamic trap and becomes immobilized therein. Also disclosed are microfluidic devices which comprise at least one microchannel having at least one hydrodynamic trap, at least one focusing fluid inlet, said focusing fluid inlet is upstream of the hydrodynamic trap such that a focusing fluid introduced therein results in a virtual channel of a sample fluid when present which preferentially flows toward the hydrodynamic trap.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2014},

  month        = {8}

}

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Works referencing / citing this record:

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Title: Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap

Abstract

Citation Formats

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