Tricyclic gyrase inhibitors
Abstract
Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1532007
- Patent Number(s):
- 9732083
- Application Number:
- 13/496,188
- Assignee:
- Merck Sharp & Dohme Corp. (New York, NY); Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
- DOE Contract Number:
- HHSN272200800042C; TC02128.0
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2012-03-14
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, and Jung, Michael. Tricyclic gyrase inhibitors. United States: N. p., 2017.
Web.
Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, & Jung, Michael. Tricyclic gyrase inhibitors. United States.
Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, and Jung, Michael. Tue .
"Tricyclic gyrase inhibitors". United States. https://www.osti.gov/servlets/purl/1532007.
@article{osti_1532007,
title = {Tricyclic gyrase inhibitors},
author = {Bensen, Daniel and Chen, Zhiyong and Finn, John and Lam, Thanh To and Lee, Suk Joong and Li, Xiaoming and Phillipson, Douglas W. and Tari, Leslie William and Trzoss, Michael and Zhang, Junhu and Lightstone, Felice C. and Nguyen, Toan B. and Wong, Sergio E. and Aristoff, Paul and Jung, Michael},
abstractNote = {Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {8}
}
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