skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Tricyclic gyrase inhibitors

Abstract

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Inventors:
; ; ; ; ; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1532007
Patent Number(s):
9732083
Application Number:
13/496,188
Assignee:
Merck Sharp & Dohme Corp. (New York, NY); Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
DOE Contract Number:  
HHSN272200800042C; TC02128.0
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012-03-14
Country of Publication:
United States
Language:
English

Citation Formats

Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, and Jung, Michael. Tricyclic gyrase inhibitors. United States: N. p., 2017. Web.
Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, & Jung, Michael. Tricyclic gyrase inhibitors. United States.
Bensen, Daniel, Chen, Zhiyong, Finn, John, Lam, Thanh To, Lee, Suk Joong, Li, Xiaoming, Phillipson, Douglas W., Tari, Leslie William, Trzoss, Michael, Zhang, Junhu, Lightstone, Felice C., Nguyen, Toan B., Wong, Sergio E., Aristoff, Paul, and Jung, Michael. Tue . "Tricyclic gyrase inhibitors". United States. https://www.osti.gov/servlets/purl/1532007.
@article{osti_1532007,
title = {Tricyclic gyrase inhibitors},
author = {Bensen, Daniel and Chen, Zhiyong and Finn, John and Lam, Thanh To and Lee, Suk Joong and Li, Xiaoming and Phillipson, Douglas W. and Tari, Leslie William and Trzoss, Michael and Zhang, Junhu and Lightstone, Felice C. and Nguyen, Toan B. and Wong, Sergio E. and Aristoff, Paul and Jung, Michael},
abstractNote = {Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {8}
}

Patent:

Save / Share:

Works referenced in this record:

Pyrimido4,5-B!indoles
patent, August 1998


Aminoalkyl substituted 9H-pyridino[2,3-b] indole and 9H-pyrimidino[4,5-b] indole derivatives
patent, November 2000