Method for atomic layer deposition
Abstract
An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid-phase support to produce a coupled-product.
- Inventors:
- Issue Date:
- Research Org.:
- STC.UNM, Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1531980
- Patent Number(s):
- 9605344
- Application Number:
- 14/917,566
- Assignee:
- STC.UNM (Albuquerque, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C23 - COATING METALLIC MATERIAL C23C - COATING METALLIC MATERIAL
- DOE Contract Number:
- FA 9550-10-1-0054; FG02-02ER15368
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2014-09-12
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Jiang, Ying-Bing, Cecchi, Joseph L., Fu, Yaqin, and Brinker, C. Jeffrey. Method for atomic layer deposition. United States: N. p., 2017.
Web.
Jiang, Ying-Bing, Cecchi, Joseph L., Fu, Yaqin, & Brinker, C. Jeffrey. Method for atomic layer deposition. United States.
Jiang, Ying-Bing, Cecchi, Joseph L., Fu, Yaqin, and Brinker, C. Jeffrey. Tue .
"Method for atomic layer deposition". United States. https://www.osti.gov/servlets/purl/1531980.
@article{osti_1531980,
title = {Method for atomic layer deposition},
author = {Jiang, Ying-Bing and Cecchi, Joseph L. and Fu, Yaqin and Brinker, C. Jeffrey},
abstractNote = {An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid-phase support to produce a coupled-product.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2017},
month = {3}
}
Works referenced in this record:
[Microwave-Assisted Peptide Synthesis]
patent-application, December 2004
- Collins, Jonathan Mckinno; Lambert, Joseph Joshua; Collins, Michael John
- US Patent Application 10/604022; 20040260059
Solid-phase mediated synthesis of molecular microarrays
patent-application, May 2008
- Sundararajan, Narayan; Rajasekaran, John J.; Xu, Guangyu
- US Patent Application 11/585413; 20080108149
Vapor Deposition of Biomolecules
patent-application, August 2010
- Gazit, Ehud; Adler-Abramovich, Lihi; Aronov, Daniel
- US Patent Application 12/678168; 20100204443
Massively parallel synthesis of biopolymeric arrays
patent-application, July 2007
- Rajasekaran, John J.; Cabezas, Edelmira; Fidanza, Jacqueline A.
- US Patent Application 11/322268; 20070154946
Works referencing / citing this record:
Synthesis of hydantoin containing peptide products
patent, October 2018
- Henkel, Bernd
- US Patent Document 10,087,221