Title: Optical sensor comprising diffraction gratings with functionalized pores and method of detecting analytes using the sensor

Abstract

Diffraction gratings comprising a substrate with protrusions extending therefrom. In one embodiment, the protrusions are made of a porous material, for example porous silicon with a porosity of greater than about 10%. The diffraction grating may also be constructed from multiple layers of porous material, for example porous silicon with a porosity of greater than about 10%, with protrusion of attached thereto. In some embodiments the protrusions may be made from photoresist or another polymeric material. The gratings are the basis for sensitive sensors. In some embodiments, the sensors are functionalized with selective binding species, to produce sensors that specifically bind to target molecules, for example chemical or biological species of interest.

Inventors:

Weiss, Sharon M.; Ryckman, Judson D.; Kang, Christopher; Liscidini, Marco; Sipe, John E.

Issue Date:

Tue Jan 08 00:00:00 EST 2013

Research Org.:

Vanderbilt Univ, Nashville, TN (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1531774

Patent Number(s):

8349617

Application Number:

12/790,905

Assignee:

Vanderbilt University (Nashville, TN)

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B29 - WORKING OF PLASTICS B29D - PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE

B - PERFORMING OPERATIONS B41 - PRINTING B41D - APPARATUS FOR THE MECHANICAL REPRODUCTION OF PRINTING SURFACES FOR STEREOTYPE PRINTING

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B - PERFORMING OPERATIONS B29 - WORKING OF PLASTICS B29D - PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE

B29D11/00 - Producing optical elements, e.g. lenses or prisms
B29D11/00769 - {Producing diffraction gratings}

B - PERFORMING OPERATIONS B41 - PRINTING B41D - APPARATUS FOR THE MECHANICAL REPRODUCTION OF PRINTING SURFACES FOR STEREOTYPE PRINTING

B41D7/00 - Shaping elastic or deformable material, e.g. rubber, plastics material, to form printing surfaces

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

Y10T436/143333 - Saccharide [e.g., DNA, etc.]

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DOE Contract Number:  

W911 NF-09-1-0101

Resource Type:

Patent

Resource Relation:

Patent File Date: 2010-05-31

Country of Publication:

United States

Language:

English