Material deposition techniques for control of solid state aperture surface properties

Branton, Daniel; Gordon, Roy G.; Chen, Peng; Mitsui, Toshiyuki; Farmer, Damon B.; Golovchenko, Jene A.

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A01 - agriculture
A21 - baking
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Title: Material deposition techniques for control of solid state aperture surface properties

Abstract

The invention provides a method for molecular analysis. In the method, sidewalls are formed extending through a structure between two structure surfaces, to define an aperture. A layer of material is deposited on the aperture sidewalls and the two structure surfaces. The aperture with the deposited material layer is then configured in a liquid solution with a gradient in a chemical potential, between the two structure surfaces defining the aperture, that is sufficient to cause molecular translocation through the aperture.

Inventors:: Branton, Daniel; Gordon, Roy G.; Chen, Peng; Mitsui, Toshiyuki; Farmer, Damon B.; Golovchenko, Jene A.

Issue Date:: Tue Jun 26 00:00:00 EDT 2012

Research Org.:: Harvard Univ., Cambridge, MA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1531739

Patent Number(s):: 8206568

Application Number:: 11/015,349

Assignee:: President and Fellows of Harvard College (Cambridge, MA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

Show more

B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
B82Y15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/48721 - {Investigating individual macromolecules, e.g. by translocation through nanopores

Show less

DOE Contract Number:: FG02-01ER45922

Resource Type:: Patent

Resource Relation:: Patent File Date: 2004-12-17

Country of Publication:: United States

Language:: English

Citation Formats


                    Branton, Daniel, Gordon, Roy G., Chen, Peng, Mitsui, Toshiyuki, Farmer, Damon B., and Golovchenko, Jene A. Material deposition techniques for control of solid state aperture surface properties.  United States: N. p., 2012. 
        Web.

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                    Branton, Daniel, Gordon, Roy G., Chen, Peng, Mitsui, Toshiyuki, Farmer, Damon B., & Golovchenko, Jene A. Material deposition techniques for control of solid state aperture surface properties.  United States.

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                    Branton, Daniel, Gordon, Roy G., Chen, Peng, Mitsui, Toshiyuki, Farmer, Damon B., and Golovchenko, Jene A. Tue .  
        "Material deposition techniques for control of solid state aperture surface properties".  United States.  https://www.osti.gov/servlets/purl/1531739.

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@article{osti_1531739,

  title        = {Material deposition techniques for control of solid state aperture surface properties},

  author       = {Branton, Daniel and Gordon, Roy G. and Chen, Peng and Mitsui, Toshiyuki and Farmer, Damon B. and Golovchenko, Jene A.},

  abstractNote = {The invention provides a method for molecular analysis. In the method, sidewalls are formed extending through a structure between two structure surfaces, to define an aperture. A layer of material is deposited on the aperture sidewalls and the two structure surfaces. The aperture with the deposited material layer is then configured in a liquid solution with a gradient in a chemical potential, between the two structure surfaces defining the aperture, that is sufficient to cause molecular translocation through the aperture.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Jun 26 00:00:00 EDT 2012},

  month        = {Tue Jun 26 00:00:00 EDT 2012}

}

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Title: Material deposition techniques for control of solid state aperture surface properties

Abstract

Citation Formats

Phase-shifting lithographic masks having phase-shifting layers of differing compositions patent, April 1995

Ion beam etching of metal oxide ceramics patent, September 1993

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ALD reactor and method with controlled wall temperature patent-application, October 2002

Microarray based affinity purification and analysis device coupled with solid state nanopore electrodes patent-application, October 2005

Adjustable nanopore, nanotome, and nanotweezer patent, March 2004

System with nano-scale conductor and nano-opening patent, March 2005

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Denaturation of double-stranded nucleic acids patent, March 2001

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Radical-assisted sequential CVD patent, March 2001

Molecular Characterization with Carbon Nanotube Control patent-application, July 2008

Ultra-fast nucleic acid sequencing device and a method for making and using the same patent, July 2002

Nanopore system using nanotubes and C60 molecules patent, July 2005

Methods for surface modification of silica for use in capillary zone electrophoresis and chromatography patent, August 2004

Ion-beam machining method and apparatus patent, June 1990

Molecular Characterization with Molecular Speed Control patent-application, June 2011

Catalytic nanoporous membranes patent-application, March 2005

Capture, recapture, and trapping of molecules with a nanopore patent-application, May 2009

Method and apparatus for controlled manufacturing of nanometer-scale apertures patent-application, October 2006

Membrane filter and a method of manufacturing the same as well as a membrane patent, May 1998

Miniature support for thin films containing single channels or nanopores and methods for using the same patent-application, May 2002

Molecular characterization with carbon nanotube control patent, September 2010

Molecular characterization with carbon nanotube control patent, December 2008

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Pulsed ion beam control of solid state features patent, October 2006

Ultra-fast nucleic acid sequencing device and a method for making and using the same patent, February 2006

Processing method and apparatus using focused energy beam patent, November 1997

Methods and apparatuses for stretching polymers patent, February 2004

Control of solid state dimensional features patent, October 2002

Molecular and atomic scale evaluation of biopolymers patent, September 2003

Carbon nanotube synthesis for nanopore devices patent-application, May 2009

Molecular characterization with carbon nanotube control patent-application, October 2008

Reducing background fluorescence in MEMS materials by low energy ion beam treatment patent, May 2017

Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels patent, May 2017

Efficient optical analysis of polymers using arrays of nanostructures patent, April 2017

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Nanopore-based nucleic acid analysis with mixed FRET detection patent, January 2018

Methods for sequencing a biomolecule by detecting relative positions of hybridized probes patent, July 2017

Ultrafast sequencing of biological polymers using a labeled nanopore patent, July 2014

Nanopore-based polymer analysis with mutually-quenching fluorescent labels patent, February 2018

Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof patent, February 2018

Devices and methods for determining the length of biopolymers and distances between probes bound thereto patent, August 2017

Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof patent, October 2018

Ultrafast sequencing of biological polymers using a labeled nanopore patent, March 2016

Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation patent, March 2018

Phase-shifting lithographic masks having phase-shifting layers of differing compositions
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Ion beam etching of metal oxide ceramics
patent, September 1993

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ALD reactor and method with controlled wall temperature
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Microarray based affinity purification and analysis device coupled with solid state nanopore electrodes
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Adjustable nanopore, nanotome, and nanotweezer
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System with nano-scale conductor and nano-opening
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Nanopump device for analyzing DNA sequences
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Denaturation of double-stranded nucleic acids
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Nanopore separation devices and methods of using same
patent-application, April 2006

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Method and apparatus for controlled manufacturing of nanometer-scale apertures
patent-application, October 2006

Membrane filter and a method of manufacturing the same as well as a membrane
patent, May 1998

Miniature support for thin films containing single channels or nanopores and methods for using the same
patent-application, May 2002

Molecular characterization with carbon nanotube control
patent, September 2010

Molecular characterization with carbon nanotube control
patent, December 2008

ALD method to improve surface coverage
patent-application, July 2002

Pulsed ion beam control of solid state features
patent, October 2006

Ultra-fast nucleic acid sequencing device and a method for making and using the same
patent, February 2006

Processing method and apparatus using focused energy beam
patent, November 1997

Methods and apparatuses for stretching polymers
patent, February 2004

Control of solid state dimensional features
patent, October 2002

Molecular and atomic scale evaluation of biopolymers
patent, September 2003

Carbon nanotube synthesis for nanopore devices
patent-application, May 2009

Molecular characterization with carbon nanotube control
patent-application, October 2008

Reducing background fluorescence in MEMS materials by low energy ion beam treatment
patent, May 2017

Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
patent, May 2017

Efficient optical analysis of polymers using arrays of nanostructures
patent, April 2017

Molecular characterization with molecular speed control
patent, March 2016

Molecular characterization device
patent, March 2019

Nanopore-based nucleic acid analysis with mixed FRET detection
patent, January 2018

Methods for sequencing a biomolecule by detecting relative positions of hybridized probes
patent, July 2017

Ultrafast sequencing of biological polymers using a labeled nanopore
patent, July 2014

Nanopore-based polymer analysis with mutually-quenching fluorescent labels
patent, February 2018

Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
patent, February 2018

Devices and methods for determining the length of biopolymers and distances between probes bound thereto
patent, August 2017

Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
patent, October 2018

Ultrafast sequencing of biological polymers using a labeled nanopore
patent, March 2016

Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation
patent, March 2018