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Title: Micro fluidic system for single molecule imaging

Abstract

Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten the polymeric molecules and attach the straightened molecules to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge.

Inventors:
; ;
Issue Date:
Research Org.:
Wisconsin Alumni Research Foundation, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1531728
Patent Number(s):
8,142,708
Application Number:
10/713,898
Assignee:
Wisconsin Alumni Research Foundation (Madison, WI)
DOE Contract Number:  
FG02-99ER62830; NIH HG00225
Resource Type:
Patent
Resource Relation:
Patent File Date: 2002-10-18
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Schwartz, David C., Dimalanta, Eileen T., and de Pablo, Juan J. Micro fluidic system for single molecule imaging. United States: N. p., 2012. Web.
Schwartz, David C., Dimalanta, Eileen T., & de Pablo, Juan J. Micro fluidic system for single molecule imaging. United States.
Schwartz, David C., Dimalanta, Eileen T., and de Pablo, Juan J. Tue . "Micro fluidic system for single molecule imaging". United States. https://www.osti.gov/servlets/purl/1531728.
@article{osti_1531728,
title = {Micro fluidic system for single molecule imaging},
author = {Schwartz, David C. and Dimalanta, Eileen T. and de Pablo, Juan J.},
abstractNote = {Laminar flow of a carrier liquid and polymeric molecules through micro-channels is used to straighten the polymeric molecules and attach the straightened molecules to a wall of the micro-channel for subsequent treatment and analysis. Micro-channels can be manufactured using an elastic molding material. One micro-channel embodiment provides fluid flow using a standard laboratory centrifuge.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {3}
}

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Works referenced in this record:

Field-inversion gel electrophoresis
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Method for optically manipulating polymer filaments
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Unitary microcapiliary and waveguide structure and method of fabrication
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