Automatic cryoloop alignment for protein crystals
Abstract
Methods and apparatus for implementing robust and efficient cryoloop auto-centering for crystal location and alignment to the x-ray beam are provided. Image processing techniques are used for recognition of the small protein crystals. The detected crystal location enables crystal positioning in the x-ray beam, and optimization of the x-ray optics such as beam profile and intensity to the size and shape of the protein crystals.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1531569
- Patent Number(s):
- 7438472
- Application Number:
- 11/774,679
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C30 - CRYSTAL GROWTH C30B - SINGLE-CRYSTAL-GROWTH
- DOE Contract Number:
- AC02-06CH11357; W-31-109-ENG-38
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2007-07-09
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS
Citation Formats
Lazarski, Krzysztof Z., and Joachimiak, Andrzej. Automatic cryoloop alignment for protein crystals. United States: N. p., 2008.
Web.
Lazarski, Krzysztof Z., & Joachimiak, Andrzej. Automatic cryoloop alignment for protein crystals. United States.
Lazarski, Krzysztof Z., and Joachimiak, Andrzej. Tue .
"Automatic cryoloop alignment for protein crystals". United States. https://www.osti.gov/servlets/purl/1531569.
@article{osti_1531569,
title = {Automatic cryoloop alignment for protein crystals},
author = {Lazarski, Krzysztof Z. and Joachimiak, Andrzej},
abstractNote = {Methods and apparatus for implementing robust and efficient cryoloop auto-centering for crystal location and alignment to the x-ray beam are provided. Image processing techniques are used for recognition of the small protein crystals. The detected crystal location enables crystal positioning in the x-ray beam, and optimization of the x-ray optics such as beam profile and intensity to the size and shape of the protein crystals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {10}
}
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Works referenced in this record:
Integrated crystal mounting and alignment system for high-throughput biological crystallography
patent, September 2007
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patent, June 2002
- Olson, Jeffrey A.; Jones, Ronald; Nienaber, Vicki
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- US Patent Document 8,571,177
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