Disruption of the cytochrome C gene in xylose-fermenting yeast

Jeffries, Thomas W.; Shi, Nian-Qing

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Title: Disruption of the cytochrome C gene in xylose-fermenting yeast

Abstract

Disclosed is a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c and enhanced fermentation of xylose relative to xylose-fermenting yeast strains in which cytochrome c is fully functional. Also disclosed is a method of producing ethanol from xylose by culturing a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c in the presence of xylose-containing material.

Inventors:: Jeffries, Thomas W.; Shi, Nian-Qing

Issue Date:: Tue Jun 06 00:00:00 EDT 2000

Research Org.:: National Renewable Energy Laboratory (NREL), Golden, CO (United States); The Consortium for Plant Biotechnology Research, Inc.

Sponsoring Org.:: USDOE

OSTI Identifier:: 1531428

Patent Number(s):: 6071729

Application Number:: 09/274,642

Assignee:: Jeffries, Thomas W., Madison, WI (United States)

Patent Classifications (CPCs):: C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

Show more

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C07K14/39 - from yeasts

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P7/06 - Ethanol, i.e. non-beverage

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/10 - Biofuels

Show less

DOE Contract Number:: AC02-83CH10093; FC05-92OR22072; HG0301; PA0 USDA

Resource Type:: Patent

Resource Relation:: Patent File Date: 1999-03-23

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats


                    Jeffries, Thomas W., and Shi, Nian-Qing. Disruption of the cytochrome C gene in xylose-fermenting yeast.  United States: N. p., 2000. 
        Web.

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                    Jeffries, Thomas W., & Shi, Nian-Qing. Disruption of the cytochrome C gene in xylose-fermenting yeast.  United States.

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                    Jeffries, Thomas W., and Shi, Nian-Qing. Tue .  
        "Disruption of the cytochrome C gene in xylose-fermenting yeast".  United States.  https://www.osti.gov/servlets/purl/1531428.

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@article{osti_1531428,

  title        = {Disruption of the cytochrome C gene in xylose-fermenting yeast},

  author       = {Jeffries, Thomas W. and Shi, Nian-Qing},

  abstractNote = {Disclosed is a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c and enhanced fermentation of xylose relative to xylose-fermenting yeast strains in which cytochrome c is fully functional. Also disclosed is a method of producing ethanol from xylose by culturing a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c in the presence of xylose-containing material.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Jun 06 00:00:00 EDT 2000},

  month        = {Tue Jun 06 00:00:00 EDT 2000}

}

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Works referenced in this record:

Diminished Respirative Growth and Enhanced Assimilative Sugar Uptake Result in Higher Specific Fermentation Rates by the Mutant Pichia stipitis FPL-061
book, January 1997

Sreenath, Hassan K.; Jeffries, Thomas W.
Biotechnology for Fuels and Chemicals
https://doi.org/10.1007/978-1-4612-2312-2_11

Xylose-fermenting yeast mutants
patent, June 1992

Jeffries, Thomas W.; Livingston, Philip
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Cloning and disruption of the b-isopropylmalate dehydrogenase gene ( LEU2 ) of Pichia stipitis with URA3 and recovery of the double auxotroph
journal, February 1998

Lu, P.; Davis, B. P.; Hendrick, J.
Applied Microbiology and Biotechnology, Vol. 49, Issue 2
https://doi.org/10.1007/s002530051150

Existence of Cyanide-Insensitive Respiration in the Yeast Pichia stipitis and Its Possible Influence on Product Formation during Xylose Utilization.
journal, January 1995

Jeppsson, H.; Alexander, N. J.; Hahn-Hagerdal, B.
Applied and environmental microbiology, Vol. 61, Issue 7
https://doi.org/10.1128/AEM.61.7.2596-2600.1995

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Title: Disruption of the cytochrome C gene in xylose-fermenting yeast

Abstract

Citation Formats

Diminished Respirative Growth and Enhanced Assimilative Sugar Uptake Result in Higher Specific Fermentation Rates by the Mutant Pichia stipitis FPL-061 book, January 1997

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Cloning and disruption of the b-isopropylmalate dehydrogenase gene ( LEU2 ) of Pichia stipitis with URA3 and recovery of the double auxotroph journal, February 1998

Existence of Cyanide-Insensitive Respiration in the Yeast Pichia stipitis and Its Possible Influence on Product Formation during Xylose Utilization. journal, January 1995

Ablation catheters and associated systems and methods patent, January 2014

Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods patent, January 2018

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Non-recombinant Saccharomyces strains that grow on xylose patent, September 2012

Molecular redundant sequencing patent, August 2017

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Molecular redundant sequencing patent, June 2015

Non-recombinant saccharomyces strains that grow on xylose patent, January 2017

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Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods patent, November 2014

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Diminished Respirative Growth and Enhanced Assimilative Sugar Uptake Result in Higher Specific Fermentation Rates by the Mutant Pichia stipitis FPL-061
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patent, June 1992

Cloning and disruption of the b-isopropylmalate dehydrogenase gene ( LEU2 ) of Pichia stipitis with URA3 and recovery of the double auxotroph
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