Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors

Title: Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors

Abstract

TOF-PET detector systems, and methods for imaging photon-emitting samples using the detector systems, are provided. The TOF-PET detector systems use large-area photodetectors with extremely high time-resolution and an approach to data collection and analysis that allows for the use of inexpensive low-density scintillator materials. The TOF-PET detector systems are characterized by their ability to identify, on a statistical basis, the transverse and depth location of the first of the series of energy deposition events that are generated when a gamma photon enters the low-density scintillator material.

Inventors:: Frisch, Henry J.; Oberla, Eric J.; Kim, Hee -Jong; Yeh, Minfang

Issue Date:: 2018-11-20

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1531371

Patent Number(s):: 10132942

Application Number:: 15/553,275

Assignee:: The University of Chicago (Chicago, IL); Brookhaven Science Associates, LLC (Upton, NY)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01T - MEASUREMENT OF NUCLEAR OR X-RADIATION

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

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G - PHYSICS G01 - MEASURING G01T - MEASUREMENT OF NUCLEAR OR X-RADIATION
G01T1/2985 - {In depth localisation, e.g. using positron emitters
G01T1/204 - the detector being a liquid
G01T1/2018 - {Scintillation-photodiode combination}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B6/037 - {Emission tomography

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DOE Contract Number:: AC02-98CH10886; PHY-1066014; SC0008172; SC0012704

Resource Type:: Patent

Resource Relation:: Patent File Date: 2016-04-08

Country of Publication:: United States

Language:: English

Citation Formats


                    Frisch, Henry J., Oberla, Eric J., Kim, Hee -Jong, and Yeh, Minfang. Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors.  United States: N. p., 2018. 
        Web.

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                    Frisch, Henry J., Oberla, Eric J., Kim, Hee -Jong, & Yeh, Minfang. Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors.  United States.

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                    Frisch, Henry J., Oberla, Eric J., Kim, Hee -Jong, and Yeh, Minfang. Tue .  
        "Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors".  United States.  https://www.osti.gov/servlets/purl/1531371.

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@article{osti_1531371,

  title        = {Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors},

  author       = {Frisch, Henry J. and Oberla, Eric J. and Kim, Hee -Jong and Yeh, Minfang},

  abstractNote = {TOF-PET detector systems, and methods for imaging photon-emitting samples using the detector systems, are provided. The TOF-PET detector systems use large-area photodetectors with extremely high time-resolution and an approach to data collection and analysis that allows for the use of inexpensive low-density scintillator materials. The TOF-PET detector systems are characterized by their ability to identify, on a statistical basis, the transverse and depth location of the first of the series of energy deposition events that are generated when a gamma photon enters the low-density scintillator material.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2018},

  month        = {11}

}

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Works referenced in this record:

PET detector system with improved capabilities for quantification
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Degenhardt, Carsten; Buckler, Andrew J.
US Patent Document 8,476,593
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Griesmer, Jerome J.; Laurence, Thomas Leroy
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A design of a PET detector using micro-channel plate photomultipliers with transmission-line readout
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Kim, H.; Frisch, H.; Chen, C. -T.
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DiFilippo, Frank P.; Heller, Mark H.
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Title: Positron-emission tomography detector systems based on low-density liquid scintillators and precise time-resolving photodetectors

Abstract

Citation Formats

PET detector system with improved capabilities for quantification patent, July 2013

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A design of a PET detector using micro-channel plate photomultipliers with transmission-line readout journal, October 2010

Nuclear imaging using variable weighting patent, August 1998

PET detector system with improved capabilities for quantification
patent, July 2013

Focus on time-of-flight PET: the benefits of improved time resolution
journal, January 2011

Achieving accurate time-of-flight calibrations with a stationary coincidence point source
patent, August 2008

A design of a PET detector using micro-channel plate photomultipliers with transmission-line readout
journal, October 2010

Nuclear imaging using variable weighting
patent, August 1998