Oxygen tolerant hydrogenase by mutating electron supply pathway
Abstract
Compositions and methods are provided for an O2 tolerant Fe—Fe hydrogenase. The hydrogenases of the invention comprise specific amino acid substitutions relative to the native, or wild-type enzymes.
- Inventors:
- Issue Date:
- Research Org.:
- Stanford Univ., CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1525029
- Patent Number(s):
- 10221401
- Application Number:
- 15/255,833
- Assignee:
- The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- SC0002010
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2016-09-02
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Swartz, James Robert, and Koo, Jamin. Oxygen tolerant hydrogenase by mutating electron supply pathway. United States: N. p., 2019.
Web.
Swartz, James Robert, & Koo, Jamin. Oxygen tolerant hydrogenase by mutating electron supply pathway. United States.
Swartz, James Robert, and Koo, Jamin. Tue .
"Oxygen tolerant hydrogenase by mutating electron supply pathway". United States. https://www.osti.gov/servlets/purl/1525029.
@article{osti_1525029,
title = {Oxygen tolerant hydrogenase by mutating electron supply pathway},
author = {Swartz, James Robert and Koo, Jamin},
abstractNote = {Compositions and methods are provided for an O2 tolerant Fe—Fe hydrogenase. The hydrogenases of the invention comprise specific amino acid substitutions relative to the native, or wild-type enzymes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {3}
}
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Works referenced in this record:
Cell-free extracts and synthesis of active hydrogenase
patent, April 2008
- Swartz, James R.; Boyer, Marcus Emil; Stapleton, James Alan
- US Patent Document 7,351,563
Vitro protein synthesis using glycolytic intermediates as an energy source
patent, January 2002
- Swartz, James R.; Kim, Dong-Myung
- US Patent Document 6,337,191