Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction

Title: Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction

Abstract

A stiffener-reinforced microelectrode array probe and fabrication method using wicking channel-distributed adhesives which temporarily adheres a flexible device onto a rigid stiffener for insertion and extraction. Assembly is by dispensing a liquid adhesive into a narrow open groove wicking channel formed on the stiffener so that the adhesive is wicked along and tills the channel by capillary action, and adhering the adhesive-filled bonding side of the elongated section of the rigid substrate to a flexible device.

Inventors:: Shah, Kedar G.; George, Diane; Pannu, Satinderpall S.; Felix, Sarah

Issue Date:: 2019-02-26

Research Org.:: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1525007

Patent Number(s):: 10214001

Application Number:: 14/376,557

Assignee:: Lawrence Livermore National Security, LLC (Livermore, CA)

Patent Classifications (CPCs):: Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

B - PERFORMING OPERATIONS B32 - LAYERED PRODUCTS B32B - LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM

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Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T428/24612 - Composite web or sheet

B - PERFORMING OPERATIONS B32 - LAYERED PRODUCTS B32B - LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
B32B37/1284 - {Application of adhesive}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B90/11 - with guides for needles or instruments, e.g. arcuate slides or ball joints

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
A61N1/0551 - {Spinal or peripheral nerve electrodes}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B5/04001 - {adapted to neuroelectric signals, e.g. nerve impulses}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
A61N1/05 - for implantation or insertion into the body, e.g. heart electrode
A61N1/0534 - {Electrodes for deep brain stimulation}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T156/10 - Methods of surface bonding and/or assembly therefor

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B2562/125 - characterised by the manufacture of electrodes

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DOE Contract Number:: AC52-07NA27344

Resource Type:: Patent

Resource Relation:: Patent File Date: 2013-02-04

Country of Publication:: United States

Language:: English

Citation Formats


                    Shah, Kedar G., George, Diane, Pannu, Satinderpall S., and Felix, Sarah. Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction.  United States: N. p., 2019. 
        Web.

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                    Shah, Kedar G., George, Diane, Pannu, Satinderpall S., & Felix, Sarah. Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction.  United States.

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                    Shah, Kedar G., George, Diane, Pannu, Satinderpall S., and Felix, Sarah. Tue .  
        "Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction".  United States.  https://www.osti.gov/servlets/purl/1525007.

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@article{osti_1525007,

  title        = {Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction},

  author       = {Shah, Kedar G. and George, Diane and Pannu, Satinderpall S. and Felix, Sarah},

  abstractNote = {A stiffener-reinforced microelectrode array probe and fabrication method using wicking channel-distributed adhesives which temporarily adheres a flexible device onto a rigid stiffener for insertion and extraction. Assembly is by dispensing a liquid adhesive into a narrow open groove wicking channel formed on the stiffener so that the adhesive is wicked along and tills the channel by capillary action, and adhering the adhesive-filled bonding side of the elongated section of the rigid substrate to a flexible device.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2019},

  month        = {2}

}

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Works referenced in this record:

Securing an optical fibre in a V-groove
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Micro fluid dispensers using flexible hollow glass fibers
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Kawabata, Masae; Izumi, Yoshihiro
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Hoffman, Arthur R.; Kendall, Arthur Harry; Rohr, Robert Lewis
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Title: Rigid stiffener-reinforced flexible neural probes, and methods of fabrication using wicking channel-distributed adhesives and tissue insertion and extraction

Abstract

Citation Formats

Securing an optical fibre in a V-groove patent, November 1999

Optical fiber connector patent, November 1990

Micro fluid dispensers using flexible hollow glass fibers patent, June 2004

Liquid crystal panel and manufacturing method the same with a thickness of the adhesive layer adjusted to eliminate a step difference patent, November 2000

Method of manufacture of multiple glass nozzle arrays patent, April 1977

Securing an optical fibre in a V-groove
patent, November 1999

Optical fiber connector
patent, November 1990

Micro fluid dispensers using flexible hollow glass fibers
patent, June 2004

Liquid crystal panel and manufacturing method the same with a thickness of the adhesive layer adjusted to eliminate a step difference
patent, November 2000

Method of manufacture of multiple glass nozzle arrays
patent, April 1977