Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

Vandersarl, Jules J.; Xu, Alexander M.; Melosh, Nicholas A.; Tayebi, Noureddine

Title: Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

Abstract

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.

Inventors:: Vandersarl, Jules J.; Xu, Alexander M.; Melosh, Nicholas A.; Tayebi, Noureddine

Issue Date:: 2018-12-11

Research Org.:: [Select One; SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1497685

Patent Number(s):: 10150947

Application Number:: 14/991,853

Assignee:: The Board of Trustees of the Leland Stanford Junior University (Stanford, CA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
B82Y40/00 - Manufacture or treatment of nanostructures
B82Y5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N2521/00 - Culture process characterised by the use of hydrostatic pressure, flow or shear forces
C12N2533/10 - Mineral substrates
C12N2533/30 - Synthetic polymers
C12N2535/00 - Supports or coatings for cell culture characterised by topography
C12N5/0068 - {General culture methods using substrates
C12N5/0075 - {using microcarriers}

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DOE Contract Number:: AC02-76-SF00515

Resource Type:: Patent

Resource Relation:: Patent File Date: 2016 Jan 08

Country of Publication:: United States

Language:: English

Citation Formats


                    Vandersarl, Jules J., Xu, Alexander M., Melosh, Nicholas A., and Tayebi, Noureddine. Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space.  United States: N. p., 2018. 
        Web.

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                    Vandersarl, Jules J., Xu, Alexander M., Melosh, Nicholas A., & Tayebi, Noureddine. Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space.  United States.

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                    Vandersarl, Jules J., Xu, Alexander M., Melosh, Nicholas A., and Tayebi, Noureddine. Tue .  
        "Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space".  United States.  https://www.osti.gov/servlets/purl/1497685.

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@article{osti_1497685,

  title        = {Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space},

  author       = {Vandersarl, Jules J. and Xu, Alexander M. and Melosh, Nicholas A. and Tayebi, Noureddine},

  abstractNote = {In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2018},

  month        = {12}

}

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A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis
journal, January 2006

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US Patent Document 8,808,516
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Fabrication of high density metallic nanowires and nanotubes for cell culture studies
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Tian, J. H.; Hu, J.; Zhang, F.
Microelectronic Engineering, Vol. 88, Issue 8, p. 1702-1706
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Compositions comprising nanostructures for cell, tissue and artificial organ growth, and methods for making and using same
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Jin, Sungho; Oh, Seunghan
US Patent Application 11/913062; 20090220561
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20090220561

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Title: Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space

Abstract

Citation Formats

Gigaohm resistance membrane seals with stealth probe electrodes journal, July 2010

Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner journal, September 2002

Computer simulations of bilayer membranes: Self-assembly and interfacial tension journal, May 1998

A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors journal, December 2007

Anaesthesia by the n-alkanes. A comparative study of nerve impulse blockage and the properties of black lipid bilayer membranes journal, October 1977

Vertical nanopillars for highly localized fluorescence imaging journal, February 2011

Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery journal, December 2010

Upregulation of a Silent Sodium Channel After Peripheral, but not Central, Nerve Injury in DRG Neurons journal, November 1999

Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip journal, August 2001

Polymeric biomaterials journal, January 2000

Microfabricated Devices for Enhanced Bioadhesive Drug Delivery: Attachment to and Small-Molecule Release Through a Cell Monolayer Under Flow journal, December 2009

Cells on chips journal, July 2006

Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays journal, July 2004

A cell nanoinjector based on carbon nanotubes journal, May 2007

Nanoscale porosity in polymer films: fabrication and therapeutic applications journal, January 2010

Fluidic nanotubes and devices patent-application, July 2011

The molecular mechanisms of anaesthesia journal, July 1977

Interfacing Silicon Nanowires with Mammalian Cells journal, June 2007

Whole Genome Expression Analysis Reveals Differential Effects of TiO 2 Nanotubes on Vascular Cells journal, January 2010

Hydrogels for Tissue Engineering journal, July 2001

Nanomaterials: A Membrane-Based Synthetic Approach journal, December 1994

Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues journal, December 2010

Nanoscale patterning controls inorganic–membrane interface structure journal, January 2011

Template-based synthesis of nanorod, nanowire, and nanotube arrays journal, January 2008

Integrin Signaling journal, August 1999

A Theoretical Study on the Diffusion Current at the Stationary Electrodes of Circular and Narrow Band Types journal, January 1968

Three-Dimensional, Flexible Nanoscale Field-Effect Transistors as Localized Bioprobes journal, August 2010

Electroporation for the efficient transfection of mammalian cells with DNA journal, January 1987

Shear Stress Induces Endothelial Differentiation From a Murine Embryonic Mesenchymal Progenitor Cell Line journal, September 2005

Neural Stimulation with a Carbon Nanotube Microelectrode Array journal, September 2006

Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells journal, January 2010

Matrix Elasticity Directs Stem Cell Lineage Specification journal, August 2006

Progress in understanding reprogramming to the induced pluripotent state journal, March 2011

Synthesis and Surface Engineering of Complex Nanostructures by Atomic Layer Deposition journal, November 2007

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering journal, January 2005

Sensors for Electrochemical, Electrical or Topographical Analysis patent-application, September 2006

Fusion of biomimetic stealth probes into lipid bilayer cores journal, March 2010

The Chemotactic Effect of Mixtures of Antibody and Antigen on Polymorphonuclear Leucocytes journal, March 1962

Nanoelectrodes and Nanotips for Recording Transmembrane Currents in a Plurality of Cells patent-application, September 2004

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space patent, February 2016

Non-invasive method of electroporation mediated by carbon nanotubes and device for putting the method into practice patent-application, February 2010

Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice. journal, April 1981

Generation of Solution and Surface Gradients Using Microfluidic Systems journal, October 2000

Generation of Gradients Having Complex Shapes Using Microfluidic Networks journal, March 2001

The origins and the future of microfluidics journal, July 2006

Neutral particle nanopatterning for nonplanar multimodal neural probes patent-application, August 2011

The Gap Junction Communication Channel journal, February 1996

Nerve-growth-factor-dependent neurite outgrowth assay; a research model for chemotherapy-induced neuropathy journal, November 1995

Patterned Protein Layers on Solid Substrates by Thin Stamp Microcontact Printing journal, February 1998

Synthetic DNA delivery systems journal, January 2000

Molecular characterization of mitochondrial apoptosis-inducing factor journal, February 1999

Organ chips and uses thereof patent-application, November 2014

Polymeric Systems for Controlled Drug Release journal, November 1999

New perspectives in cell adhesion: RGD and integrins journal, October 1987

GeneCards Version 3: the human gene integrator journal, January 2010

Cell Adhesion and Spreading Behavior on Vertically Aligned Silicon Nanowire Arrays journal, November 2008

Endothelial cell polarization and chemotaxis in a microfluidic device journal, January 2008

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles journal, May 2008

Spatially controlled cell engineering on biodegradable polymer surfaces journal, November 1998

Nanofountain-Probe-Based High-Resolution Patterning and Single-Cell Injection of Functionalized Nanodiamonds journal, July 2009

Method and apparatus for measuring a state variable patent, April 2002

Carbon nanotube array and method for forming same patent, January 2007

Stimulation of Neural Cells by Lateral Currents in Conductive Layer-by-Layer Films of Single-Walled Carbon Nanotubes journal, November 2006

Semiconductor Nanowire: What’s Next? journal, May 2010

Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix journal, October 2000

Electrodeposition of nickel nanowires and nanotubes using various templates journal, December 2008

Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence journal, February 1999

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Method of Fabricating a Three-Dimensional Nanostructure patent-application, May 2007

TiO 2 nanotubes on Ti: Influence of nanoscale morphology on bone cell-materials interaction journal, June 2009

Potent antibody therapeutics by design journal, April 2006

Biomolecular gradients in cell culture systems journal, January 2008

Microfluidic “jets” for generating steady-state gradients of soluble molecules on open surfaces journal, September 2006

The stem-cell niche as an entity of action journal, June 2006

Probe Arrangement patent-application, December 2008

Device for transporting small volumes of a fluid, in particular a micropump or microvalve patent-application, May 2013

Intracellular Molecular Delivery Based on Nanostructure Injectors patent-application, October 2012

Gigaohm resistance membrane seals with stealth probe electrodes
journal, July 2010

Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner
journal, September 2002

Computer simulations of bilayer membranes: Self-assembly and interfacial tension
journal, May 1998

A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors
journal, December 2007

Anaesthesia by the n-alkanes. A comparative study of nerve impulse blockage and the properties of black lipid bilayer membranes
journal, October 1977

Vertical nanopillars for highly localized fluorescence imaging
journal, February 2011

Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery
journal, December 2010

Upregulation of a Silent Sodium Channel After Peripheral, but not Central, Nerve Injury in DRG Neurons
journal, November 1999

Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip
journal, August 2001

Polymeric biomaterials
journal, January 2000

Microfabricated Devices for Enhanced Bioadhesive Drug Delivery: Attachment to and Small-Molecule Release Through a Cell Monolayer Under Flow
journal, December 2009

Cells on chips
journal, July 2006

Tracking Gene Expression after DNA Delivery Using Spatially Indexed Nanofiber Arrays
journal, July 2004

A cell nanoinjector based on carbon nanotubes
journal, May 2007

Nanoscale porosity in polymer films: fabrication and therapeutic applications
journal, January 2010

Fluidic nanotubes and devices
patent-application, July 2011

The molecular mechanisms of anaesthesia
journal, July 1977

Interfacing Silicon Nanowires with Mammalian Cells
journal, June 2007

Whole Genome Expression Analysis Reveals Differential Effects of TiO ₂ Nanotubes on Vascular Cells
journal, January 2010

Hydrogels for Tissue Engineering
journal, July 2001

Nanomaterials: A Membrane-Based Synthetic Approach
journal, December 1994

Alterations in gene expression of human vascular endothelial cells associated with nanotopographic cues
journal, December 2010

Nanoscale patterning controls inorganic–membrane interface structure
journal, January 2011

Template-based synthesis of nanorod, nanowire, and nanotube arrays
journal, January 2008

Integrin Signaling
journal, August 1999

A Theoretical Study on the Diffusion Current at the Stationary Electrodes of Circular and Narrow Band Types
journal, January 1968

Three-Dimensional, Flexible Nanoscale Field-Effect Transistors as Localized Bioprobes
journal, August 2010

Electroporation for the efficient transfection of mammalian cells with DNA
journal, January 1987

Shear Stress Induces Endothelial Differentiation From a Murine Embryonic Mesenchymal Progenitor Cell Line
journal, September 2005

Neural Stimulation with a Carbon Nanotube Microelectrode Array
journal, September 2006

Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells
journal, January 2010

Matrix Elasticity Directs Stem Cell Lineage Specification
journal, August 2006

Progress in understanding reprogramming to the induced pluripotent state
journal, March 2011

Synthesis and Surface Engineering of Complex Nanostructures by Atomic Layer Deposition
journal, November 2007

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
journal, January 2005

Sensors for Electrochemical, Electrical or Topographical Analysis
patent-application, September 2006

Fusion of biomimetic stealth probes into lipid bilayer cores
journal, March 2010

The Chemotactic Effect of Mixtures of Antibody and Antigen on Polymorphonuclear Leucocytes
journal, March 1962

Nanoelectrodes and Nanotips for Recording Transmembrane Currents in a Plurality of Cells
patent-application, September 2004

Nanotube structures, methods of making nanotube structures, and methods of accessing intracellular space
patent, February 2016

Non-invasive method of electroporation mediated by carbon nanotubes and device for putting the method into practice
patent-application, February 2010

Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice.
journal, April 1981

Generation of Solution and Surface Gradients Using Microfluidic Systems
journal, October 2000

Generation of Gradients Having Complex Shapes Using Microfluidic Networks
journal, March 2001

The origins and the future of microfluidics
journal, July 2006

Neutral particle nanopatterning for nonplanar multimodal neural probes
patent-application, August 2011

The Gap Junction Communication Channel
journal, February 1996

Nerve-growth-factor-dependent neurite outgrowth assay; a research model for chemotherapy-induced neuropathy
journal, November 1995

Patterned Protein Layers on Solid Substrates by Thin Stamp Microcontact Printing
journal, February 1998

Synthetic DNA delivery systems
journal, January 2000

Molecular characterization of mitochondrial apoptosis-inducing factor
journal, February 1999

Organ chips and uses thereof
patent-application, November 2014

Polymeric Systems for Controlled Drug Release
journal, November 1999

New perspectives in cell adhesion: RGD and integrins
journal, October 1987

GeneCards Version 3: the human gene integrator
journal, January 2010

Cell Adhesion and Spreading Behavior on Vertically Aligned Silicon Nanowire Arrays
journal, November 2008

Endothelial cell polarization and chemotaxis in a microfluidic device
journal, January 2008

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles
journal, May 2008

Spatially controlled cell engineering on biodegradable polymer surfaces
journal, November 1998

Nanofountain-Probe-Based High-Resolution Patterning and Single-Cell Injection of Functionalized Nanodiamonds
journal, July 2009

Method and apparatus for measuring a state variable
patent, April 2002

Carbon nanotube array and method for forming same
patent, January 2007

Stimulation of Neural Cells by Lateral Currents in Conductive Layer-by-Layer Films of Single-Walled Carbon Nanotubes
journal, November 2006

Semiconductor Nanowire: What’s Next?
journal, May 2010

Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix
journal, October 2000

Electrodeposition of nickel nanowires and nanotubes using various templates
journal, December 2008

Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence
journal, February 1999

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
journal, January 2003

Method of Fabricating a Three-Dimensional Nanostructure
patent-application, May 2007

TiO ₂ nanotubes on Ti: Influence of nanoscale morphology on bone cell-materials interaction
journal, June 2009

Potent antibody therapeutics by design
journal, April 2006

Biomolecular gradients in cell culture systems
journal, January 2008

Microfluidic “jets” for generating steady-state gradients of soluble molecules on open surfaces
journal, September 2006

The stem-cell niche as an entity of action
journal, June 2006

Probe Arrangement
patent-application, December 2008

Device for transporting small volumes of a fluid, in particular a micropump or microvalve
patent-application, May 2013

Intracellular Molecular Delivery Based on Nanostructure Injectors
patent-application, October 2012

Role of Titanium Surface Topography and Surface Wettability on Focal Adhesion Kinase Mediated Signaling in Fibroblasts
journal, May 2011

Nanopipette apparatus for manipulating cells
patent-application, September 2012

Devices and methods for programmable microscale manipulation of fluids
patent, December 2006