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Title: Spectrally resolved super-resolution microscopy and ultrahigh-throughput single-molecule spectroscopy

Abstract

Systems and methods for spectrally resolved super-resolution microscopy (SRM) and ultrahigh-throughput single-molecule spectroscopy to synchronously and rapidly measure the fluorescence spectra and positions of millions of single molecules in dense samples.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1497067
Patent Number(s):
10151701
Application Number:
15/892,575
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2018 Feb 09
Country of Publication:
United States
Language:
English

Citation Formats

Xu, Ke, Zhang, Zhengyang, Kenny, Samuel J., Hauser, Margaret, and Li, Wan. Spectrally resolved super-resolution microscopy and ultrahigh-throughput single-molecule spectroscopy. United States: N. p., 2018. Web.
Xu, Ke, Zhang, Zhengyang, Kenny, Samuel J., Hauser, Margaret, & Li, Wan. Spectrally resolved super-resolution microscopy and ultrahigh-throughput single-molecule spectroscopy. United States.
Xu, Ke, Zhang, Zhengyang, Kenny, Samuel J., Hauser, Margaret, and Li, Wan. Tue . "Spectrally resolved super-resolution microscopy and ultrahigh-throughput single-molecule spectroscopy". United States. https://www.osti.gov/servlets/purl/1497067.
@article{osti_1497067,
title = {Spectrally resolved super-resolution microscopy and ultrahigh-throughput single-molecule spectroscopy},
author = {Xu, Ke and Zhang, Zhengyang and Kenny, Samuel J. and Hauser, Margaret and Li, Wan},
abstractNote = {Systems and methods for spectrally resolved super-resolution microscopy (SRM) and ultrahigh-throughput single-molecule spectroscopy to synchronously and rapidly measure the fluorescence spectra and positions of millions of single molecules in dense samples.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {12}
}

Works referenced in this record:

High Resolution Dual-Objective Microscopy
patent-application, November 2014


Stochastic Optical Reconstruction Microscopy (STORM): A Method for Superresolution Fluorescence Imaging
journal, June 2013


Ultrahigh-Resolution Colocalization of Spectrally Separable Point-like Fluorescent Probes
journal, September 2001


Ultrahigh-throughput single-molecule spectroscopy and spectrally resolved super-resolution microscopy
journal, August 2015