Methods and kits for predicting a response to an erythropoietic agent

Title: Methods and kits for predicting a response to an erythropoietic agent

Full Record
Other Related Research

Abstract

Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent.

Inventors:: Merchant, Michael L.; Klein, Jon B.; Brier, Michael E.; Gaweda, Adam E.

Issue Date:: 2018-08-07

Research Org.:: University of Louisville Research Foundation, Inc., Louisville, KY (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1469316

Patent Number(s):: 10041956

Application Number:: 14/712,323

Assignee:: University of Louisville Research Foundation, Inc. (Louisville, KY)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

Show more

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N2333/47 - Assays involving proteins of known structure or function as defined in the subgroups
G01N2800/52 - Predicting or monitoring the response to treatment
G01N33/6893 - {related to diseases not provided for elsewhere}
G01N33/6863 - {Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors}
G01N33/68 - involving proteins, peptides or amino acids {

Show less

DOE Contract Number:: FG02-05ER6406

Resource Type:: Patent

Resource Relation:: Patent File Date: 2015 May 14

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Merchant, Michael L., Klein, Jon B., Brier, Michael E., and Gaweda, Adam E. Methods and kits for predicting a response to an erythropoietic agent.  United States: N. p., 2018. 
        Web.

Copy to clipboard


                    Merchant, Michael L., Klein, Jon B., Brier, Michael E., & Gaweda, Adam E. Methods and kits for predicting a response to an erythropoietic agent.  United States.

Copy to clipboard


                    Merchant, Michael L., Klein, Jon B., Brier, Michael E., and Gaweda, Adam E. Tue .  
        "Methods and kits for predicting a response to an erythropoietic agent".  United States.  https://www.osti.gov/servlets/purl/1469316.

Copy to clipboard


                    
@article{osti_1469316,

  title        = {Methods and kits for predicting a response to an erythropoietic agent},

  author       = {Merchant, Michael L. and Klein, Jon B. and Brier, Michael E. and Gaweda, Adam E.},

  abstractNote = {Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2018},

  month        = {8}

}

Copy to clipboard

Patent:

View Patent

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE Patents and OSTI.GOV collections:

Methods and kits for predicting a response to an erythropoietic agent

Patent Merchant, Michael L.; Klein, Jon B.; Brier, Michael E.; ...

Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. Kits for predicting a response to an erythropoietic agent are further providedmore »« less
Full Text Available
Kit for providing a technetium medical radioimaging agent

Patent Wildung, Raymond E [Richland, WA]; Garland, Thomas R [Greybull, WY]; Li, Shu-Mei W [Richland, WA]

The present invention is directed toward a kit for microbial reduction of a technetium compound to form other compounds of value in medical imaging. The technetium compound is combined in a mixture with non-growing microbial cells which contain a technetium-reducing enzyme system, a stabilizing agent and an electron donor in a saline solution under anaerobic conditions. The mixture is substantially free of an inorganic technetium reducing agent and its reduction products. The resulting product is Tc of lower oxidation states, the form of which can be partially controlled by the stabilizing agent. It has been discovered that the microorganisms Shewanellamore »« less
Full Text Available
Kits and methods of detection using cellulose binding domain fusion proteins

Patent Shoseyov, Oded [Karmey Yosef, IL]

A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Full Text Available
Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging

Patent Rose-Petruck, Christoph; Wands, Jack R.; Rand, Danielle; ...

Methods, compositions, systems, devices and kits are provided herein for preparing and using a nanoparticle composition and spatial frequency heterodyne imaging for visualizing cells or tissues. In various embodiments, the nanoparticle composition includes at least one of: a nanoparticle, a polymer layer, and a binding agent, such that the polymer layer coats the nanoparticle and is for example a polyethylene glycol, a polyelectrolyte, an anionic polymer, or a cationic polymer, and such that the binding agent that specifically binds the cells or the tissue. Methods, compositions, systems, devices and kits are provided for identifying potential therapeutic agents in a modelmore »« less
Full Text Available
Field kit and method for testing for the presence of gunshot residue

Patent Rodacy, Philip J.; Walker, Pamela K.

A field test kit for gunshot residue comprises a container having at least compartments separated by a barrier. A surface is tested by wiping it with a swab and placing the swab in a first compartment. The barrier is then breached, permitting reagent in the second compartment to flow onto the swab. The first compartment is transparent, and a color change will be observed if the reagent reacts with gunshot residue.
Full Text Available

Similar Records