skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Methods for making nucleotide probes for sequencing and synthesis

Abstract

Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.

Inventors:
; ;
Issue Date:
Research Org.:
Harvard Univ., Cambridge, MA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1464737
Patent Number(s):
10036055
Application Number:
14/284,764
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
FG02-02ER63445
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 May 22
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Church, George M., Zhang, Kun, and Chou, Joseph. Methods for making nucleotide probes for sequencing and synthesis. United States: N. p., 2018. Web.
Church, George M., Zhang, Kun, & Chou, Joseph. Methods for making nucleotide probes for sequencing and synthesis. United States.
Church, George M., Zhang, Kun, and Chou, Joseph. Tue . "Methods for making nucleotide probes for sequencing and synthesis". United States. https://www.osti.gov/servlets/purl/1464737.
@article{osti_1464737,
title = {Methods for making nucleotide probes for sequencing and synthesis},
author = {Church, George M. and Zhang, Kun and Chou, Joseph},
abstractNote = {Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {7}
}

Patent:

Save / Share:

Works referenced in this record:

Padlock probes: circularizing oligonucleotides for localized DNA detection
journal, September 1994


Circle-to-circle amplification for precise and sensitive DNA analysis
journal, March 2004


Allelic Variation in Human Gene Expression
journal, August 2002


Cell-free cloning using φ29 DNA polymerase
journal, November 2005


Allele quantification using molecular inversion probes (MIP)
journal, November 2005


Multiplexed genotyping with sequence-tagged molecular inversion probes
journal, May 2003


Mutation detection and single-molecule counting using isothermal rolling-circleamplification
journal, July 1998


Universal DNA microarray method for multiplex detection of low abundance point mutations
journal, September 1999


Multiplex PCR
patent-application, June 2003


Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA
journal, May 1998


Sequencing genomes from single cells by polymerase cloning
journal, May 2006


Toward genome-wide SNP genotyping
journal, June 2005


Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay
journal, January 2005


Parallel gene analysis with allele-specific padlock probes and tag microarrays
journal, September 2003


Parallel Genotyping of Human SNPs Using Generic High-density Oligonucleotide Tag Arrays
journal, June 2000


Signal amplification of padlock probes by rolling circle replication
journal, November 1998


Accurate multiplex gene synthesis from programmable DNA microchips
journal, December 2004