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Title: Three-dimensional electronic scaffold for cardiac applications

Abstract

Disclosed here is a three-dimensional electronic scaffold, comprising a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold, wherein the micro-strain gauges are adapted to detect contraction force. Also disclosed is a method comprising detecting and mapping intra-tissue cardiac contraction force of one or more cardiac cells or tissues disposed in a three-dimensional electronic scaffold, wherein the three-dimensional electronic scaffold comprises a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold and in contact with the cardiac cells or tissues, and wherein the micro-strain gauges are adapted to detect contraction force of the cardiac cells or tissues.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1462946
Patent Number(s):
10018615
Application Number:
15/064,044
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2016 Mar 08
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Citation Formats

Qian, Fang, Bora, Mihail, Duoss, Eric, Spadaccini, Christopher, and Zhu, Cheng. Three-dimensional electronic scaffold for cardiac applications. United States: N. p., 2018. Web.
Qian, Fang, Bora, Mihail, Duoss, Eric, Spadaccini, Christopher, & Zhu, Cheng. Three-dimensional electronic scaffold for cardiac applications. United States.
Qian, Fang, Bora, Mihail, Duoss, Eric, Spadaccini, Christopher, and Zhu, Cheng. Tue . "Three-dimensional electronic scaffold for cardiac applications". United States. https://www.osti.gov/servlets/purl/1462946.
@article{osti_1462946,
title = {Three-dimensional electronic scaffold for cardiac applications},
author = {Qian, Fang and Bora, Mihail and Duoss, Eric and Spadaccini, Christopher and Zhu, Cheng},
abstractNote = {Disclosed here is a three-dimensional electronic scaffold, comprising a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold, wherein the micro-strain gauges are adapted to detect contraction force. Also disclosed is a method comprising detecting and mapping intra-tissue cardiac contraction force of one or more cardiac cells or tissues disposed in a three-dimensional electronic scaffold, wherein the three-dimensional electronic scaffold comprises a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold and in contact with the cardiac cells or tissues, and wherein the micro-strain gauges are adapted to detect contraction force of the cardiac cells or tissues.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {7}
}

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