Mosaic conserved region HIV immunogenic polypeptides
Disclosed herein are mosaic conserved region HIV polypeptides and immunogenic polypeptides including one or more of the mosaic conserved region polypeptides. In some embodiments, the immunogenic polypeptides are included in an immunogenic composition, such as a polyvalent immunogenic composition. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject having or at risk of HIV infection. In some embodiments, the methods include inducing an immune response in a subject comprising administering to the subject at least one of the disclosed immunogenic polypeptides or a nucleic acid encoding at least one of the immunogenic polypeptides.
- Issue Date:
- OSTI Identifier:
- 1462188
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM); Oxford University Innovation Limited (Oxford, GB) LANL
- Patent Number(s):
- 10,010,606
- Application Number:
- 15/025,733
- Contract Number:
- AC52-06NA25396
- Resource Relation:
- Patent File Date: 2014 Sep 30
- Research Org:
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Sponsoring Org:
- USDOE
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
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