Ion focusing

Title: Ion focusing

Abstract

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

Inventors:: Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

Issue Date:: 2018-07-03

Research Org.:: Purdue Univ., West Lafayette, IN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1461502

Patent Number(s):: 10014169

Application Number:: 15/407,499

Assignee:: Purdue Research Foundation (West Lafayette, IN)

Patent Classifications (CPCs):: H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

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H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/26 - Mass spectrometers or separator tubes
H01J49/067 - {Ion lenses, apertures, skimmers}
H01J49/06 - Electron- or ion-optical arrangements
H01J49/10 - Ion sources
H01J49/165 - {Electrospray ionisation}

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DOE Contract Number:: FG02-06ER15807

Resource Type:: Patent

Resource Relation:: Patent File Date: 2017 Jan 17

Country of Publication:: United States

Language:: English

Citation Formats


                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. Ion focusing.  United States: N. p., 2018. 
        Web.

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                    Cooks, Robert Graham, Baird, Zane, & Peng, Wen-Ping. Ion focusing.  United States.

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                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. Tue .  
        "Ion focusing".  United States.  https://www.osti.gov/servlets/purl/1461502.

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@article{osti_1461502,

  title        = {Ion focusing},

  author       = {Cooks, Robert Graham and Baird, Zane and Peng, Wen-Ping},

  abstractNote = {The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2018},

  month        = {7}

}

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Patent Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which ismore »« less
Full Text Available
ION focusing

Patent Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which ismore »« less
Full Text Available
Method for fabricating superconducting devices using a focused ion beam

Patent Cybart, Shane A.; Cho, Ethan Y.; Dynes, Robert C.; ...

Nano-scale junctions, wires, and junction arrays are created by using a focused high-energy ion beam to direct-write insulating or poorly conducting barriers into thin films of materials that are sensitive to disorder, including superconductors, ferromagnetic materials and semiconductors.
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Title: Ion focusing

Abstract

Citation Formats

Method and apparatus for aerodynamic ion focusing patent, January 2006

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing journal, November 2011

SIMION ion optics simulations at atmospheric pressure journal, June 2005

Apparatus and method for focusing ions and charged particles at atmospheric pressure patent, June 2004

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper journal, September 2008

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition journal, April 2005

Apparatus and methods for analyzing ions patent, January 2013

Processing of giant graphene molecules by soft-landing mass spectrometry journal, March 2006

System and method for the preparation of arrays of biological or other molecules patent, August 2008

Phosphor and manufacturing method of the same, and light emitting device using the phosphor patent-application, October 2006

Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces journal, February 2006

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface journal, August 2005

Novel purified polypeptides from Pseudomonas aeruginosa patent-application, November 2005

Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids journal, January 2005

Ambient Ionization Mass Spectrometry journal, June 2010

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer journal, February 2012

Ion focusing patent, January 2017

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions journal, April 2005

Enhanced Spray Formation for Liquid Samples patent-application, June 2016

Sample analysis systems and methods of use thereof patent, July 2017

Low-Energy Ionic Collisions at Molecular Solids journal, June 2012

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow journal, December 2011

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment journal, January 2012

Ion focusing patent, November 2015

Practical implications of some recent studies in electrospray ionization fundamentals journal, January 2001

Development of an electrospray approach to deposit complex molecules on plasma modified surfaces journal, November 2003

Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions journal, September 2011

Image Mapping Spectrometers patent-application, November 2011

Microengineered vacuum interface for an ionization system patent, August 2010

Systems and methods for transfer of ions for analysis patent, April 2013

Laminated tube for the transport of charged particles contained in a gaseous medium patent, September 2005

Image mapping spectrometers patent, February 2014

Soft Landing of Complex Molecules on Surfaces journal, July 2011

Method and device for non-contact sampling and detection patent, September 2009

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays journal, February 2007

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine journal, March 2000

Discontinuous Atmospheric Pressure Interface patent-application, December 2010

The ion funnel: Theory, implementations, and applications journal, April 2009

Sampling Wand for an Ion Trap Mass Spectrometer journal, March 2011

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition journal, September 2010

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry journal, October 2009

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules journal, July 2011

From Ions In Solution To Ions In The Gas Phase journal, November 1993

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization journal, October 2004

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations journal, August 2012

Handheld Rectilinear Ion Trap Mass Spectrometer journal, September 2006

The growth and modification of materials via ion–surface processing journal, March 2002

Three-dimensional microfluidic devices fabricated in layered paper and tape journal, December 2008

Discontinuous atmospheric pressure interface patent, November 2012

A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer journal, April 1997

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS journal, November 2009

Helical Peptide Arrays on Self-Assembled Monolayer Surfaces through Soft and Reactive Landing of Mass-Selected Ions journal, August 2008

Design and Characterization of a Multisource Hand-Held Tandem Mass Spectrometer journal, October 2008

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments journal, September 2008

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications journal, March 2003

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects journal, March 2012

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters journal, February 2010

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au8 clusters journal, May 2007

Electrospray ionization for mass spectrometry of large biomolecules journal, October 1989

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface journal, September 2007

Method and system for desorption electrospray ionization patent, February 2008

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper journal, May 2008

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition journal, September 2008

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry journal, June 2006

Paper-Based Microfluidic Devices by Plasma Treatment journal, December 2008

Current status of droplet evaporation in turbulent flows journal, July 2006

Ion transport device and modes of operation thereof patent, August 2010

Method and apparatus for aerodynamic ion focusing
patent, January 2006

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing
journal, November 2011

SIMION ion optics simulations at atmospheric pressure
journal, June 2005

Apparatus and method for focusing ions and charged particles at atmospheric pressure
patent, June 2004

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper
journal, September 2008

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition
journal, April 2005

Apparatus and methods for analyzing ions
patent, January 2013

Processing of giant graphene molecules by soft-landing mass spectrometry
journal, March 2006

System and method for the preparation of arrays of biological or other molecules
patent, August 2008

Phosphor and manufacturing method of the same, and light emitting device using the phosphor
patent-application, October 2006

Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces
journal, February 2006

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface
journal, August 2005

Novel purified polypeptides from Pseudomonas aeruginosa
patent-application, November 2005

Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids
journal, January 2005

Ambient Ionization Mass Spectrometry
journal, June 2010

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer
journal, February 2012

Ion focusing
patent, January 2017

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005

Enhanced Spray Formation for Liquid Samples
patent-application, June 2016

Sample analysis systems and methods of use thereof
patent, July 2017

Low-Energy Ionic Collisions at Molecular Solids
journal, June 2012

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow
journal, December 2011

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment
journal, January 2012

Ion focusing
patent, November 2015

Practical implications of some recent studies in electrospray ionization fundamentals
journal, January 2001

Development of an electrospray approach to deposit complex molecules on plasma modified surfaces
journal, November 2003

Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions
journal, September 2011

Image Mapping Spectrometers
patent-application, November 2011

Microengineered vacuum interface for an ionization system
patent, August 2010

Systems and methods for transfer of ions for analysis
patent, April 2013

Laminated tube for the transport of charged particles contained in a gaseous medium
patent, September 2005

Image mapping spectrometers
patent, February 2014

Soft Landing of Complex Molecules on Surfaces
journal, July 2011

Method and device for non-contact sampling and detection
patent, September 2009

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays
journal, February 2007

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine
journal, March 2000

Discontinuous Atmospheric Pressure Interface
patent-application, December 2010

The ion funnel: Theory, implementations, and applications
journal, April 2009

Sampling Wand for an Ion Trap Mass Spectrometer
journal, March 2011

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition
journal, September 2010

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry
journal, October 2009

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules
journal, July 2011

From Ions In Solution To Ions In The Gas Phase
journal, November 1993

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
journal, October 2004

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations
journal, August 2012

Handheld Rectilinear Ion Trap Mass Spectrometer
journal, September 2006

The growth and modification of materials via ion–surface processing
journal, March 2002

Three-dimensional microfluidic devices fabricated in layered paper and tape
journal, December 2008

Discontinuous atmospheric pressure interface
patent, November 2012

A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer
journal, April 1997

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS
journal, November 2009

Helical Peptide Arrays on Self-Assembled Monolayer Surfaces through Soft and Reactive Landing of Mass-Selected Ions
journal, August 2008

Design and Characterization of a Multisource Hand-Held Tandem Mass Spectrometer
journal, October 2008

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments
journal, September 2008

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications
journal, March 2003

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects
journal, March 2012

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters
journal, February 2010

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au₈ clusters
journal, May 2007

Electrospray ionization for mass spectrometry of large biomolecules
journal, October 1989

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface
journal, September 2007

Method and system for desorption electrospray ionization
patent, February 2008

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper
journal, May 2008

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition
journal, September 2008

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry
journal, June 2006

Paper-Based Microfluidic Devices by Plasma Treatment
journal, December 2008

Current status of droplet evaporation in turbulent flows
journal, July 2006

Ion transport device and modes of operation thereof
patent, August 2010