Ion focusing

Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

Title: Ion focusing

Abstract

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

Inventors:: Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

Issue Date:: 2018-07-03

Research Org.:: Purdue Univ., West Lafayette, IN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1461502

Patent Number(s):: 10014169

Application Number:: 15/407,499

Assignee:: Purdue Research Foundation (West Lafayette, IN)

Patent Classifications (CPCs):: H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

Show more

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/06 - Electron- or ion-optical arrangements
H01J49/067 - {Ion lenses, apertures, skimmers}
H01J49/10 - Ion sources
H01J49/165 - {Electrospray ionisation}
H01J49/26 - Mass spectrometers or separator tubes

Show less

DOE Contract Number:: FG02-06ER15807

Resource Type:: Patent

Resource Relation:: Patent File Date: 2017 Jan 17

Country of Publication:: United States

Language:: English

Citation Formats


                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. Ion focusing.  United States: N. p., 2018. 
        Web.

Copy to clipboard


                    Cooks, Robert Graham, Baird, Zane, & Peng, Wen-Ping. Ion focusing.  United States.

Copy to clipboard


                    Cooks, Robert Graham, Baird, Zane, and Peng, Wen-Ping. Tue .  
        "Ion focusing".  United States.  https://www.osti.gov/servlets/purl/1461502.

Copy to clipboard


                    
@article{osti_1461502,

  title        = {Ion focusing},

  author       = {Cooks, Robert Graham and Baird, Zane and Peng, Wen-Ping},

  abstractNote = {The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2018},

  month        = {7}

}

Copy to clipboard

Patent:

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Method and apparatus for aerodynamic ion focusing
patent, January 2006

Lee, Edgar D.; Lee, Milton L.; Rockwood, Alan L.
US Patent Document 6,992,299
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6992299

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing
journal, November 2011

Peng, Wen-Ping; Johnson, Grant E.; Fortmeyer, Ivy C.
Phys. Chem. Chem. Phys., Vol. 13, Issue 1, p. 267-275
https://doi.org/10.1039/C0CP01457E

SIMION ion optics simulations at atmospheric pressure
journal, June 2005

Appelhans, Anthony D.; Dahl, David A.
International Journal of Mass Spectrometry, Vol. 244, Issue 1, p. 1-14
https://doi.org/10.1016/j.ijms.2005.03.010

Apparatus and method for focusing ions and charged particles at atmospheric pressure
patent, June 2004

Sheehan, Edward William; Willoughby, Ross C.
US Patent Document 6,744,041
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6744041

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper
journal, September 2008

Abe, Koji; Suzuki, Koji; Citterio, Daniel
Analytical Chemistry, Vol. 80, Issue 18, p. 6928-6934
https://doi.org/10.1021/ac800604v

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition
journal, April 2005

Tepavcevic, Sanja; Wroble, Amanda T.; Bissen, Mark
The Journal of Physical Chemistry B, Vol. 109, Issue 15, p. 7134-7140
https://doi.org/10.1021/jp0451445

Apparatus and methods for analyzing ions
patent, January 2013

Clemmer, David E.; Merenbloom, Samuel I.; Koeniger, Stormy L.
US Patent Document 8,362,420
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8362420

Processing of giant graphene molecules by soft-landing mass spectrometry
journal, March 2006

Räder, Hans Joachim; Rouhanipour, Ali; Talarico, Anna Maria
Nature Materials, Vol. 5, Issue 4, p. 276-280
https://doi.org/10.1038/nmat1597

Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method
patent-application, June 2012

Makarov, Alexander A.; Pesch, Reinhold; Malek, Robert
US Patent Application 13/413568; 20120161029
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120161029

System and method for the preparation of arrays of biological or other molecules
patent, April 2008

Cooks, Robert Graham; Ouyang, Zheng
US Patent Document 7,361,311
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7361311

Phosphor and manufacturing method of the same, and light emitting device using the phosphor
patent-application, October 2006

Sakane, Kenji; Nagatomi, Akira
US Patent Application 11/149192; 20060220520
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20060220520

Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces
journal, February 2006

Mulligan, Christopher C.; Talaty, Nari; Cooks, R. Graham
Chemical Communications, Issue 16, p. 1709-1711
https://doi.org/10.1039/b517357d

Atmospheric pressure interface ion source and mass spectrometer
patent-application, May 2014

Zhang, Xiaohua; Wang, Houle; Zhang, Hua
US Patent Application 14/235905; 20140145075
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20140145075

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface
journal, August 2005

Volný, Michael; Elam, W. Timothy; Branca, Andrew
Analytical Chemistry, Vol. 77, Issue 15, p. 4890-4896
https://doi.org/10.1021/ac0507136

Novel purified polypeptides from Pseudomonas aeruginosa
patent-application, November 2005

Edwards, Aled; Dharamsi, Akil; Vedadi, Masoud
US Patent Application 10/967671; 20050245728
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050245728

Ion focusing
patent-application, June 2016

Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping
US Patent Application 14/936223; 20160155622
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20160155622

Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids
journal, January 2005

Shiea, Jentaie; Huang, Min-Zon; HSu, Hsiu-Jung
Rapid Communications in Mass Spectrometry, Vol. 19, Issue 24, p. 3701-3704
https://doi.org/10.1002/rcm.2243

Ambient Ionization Mass Spectrometry
journal, June 2010

Huang, Min-Zong; Yuan, Cheng-Hui; Cheng, Sy-Chyi
Annual Review of Analytical Chemistry, Vol. 3, Issue 1, p. 43-65
https://doi.org/10.1146/annurev.anchem.111808.073702

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer
journal, February 2012

Garimella, Sandilya; Xu, Wei; Huang, Guangming
Journal of Mass Spectrometry, Vol. 47, Issue 2, p. 201-207
https://doi.org/10.1002/jms.2955

Ion focusing
patent, January 2017

Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping
US Patent Document 9,548,192
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9548192

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005

Cody, Robert B.; Laramée, James A.; Durst, H. Dupont
Analytical Chemistry, Vol. 77, Issue 8, p. 2297-2302
https://doi.org/10.1021/ac050162j

Charge reduction electrospray ionization ion source
patent-application, September 2002

Ebeling, Daniel D.; Westphall, Michael S.; Scalf, Mark A.
US Patent Application 09/802322; 20020125423
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20020125423

Enhanced Spray Formation for Liquid Samples
patent-application, June 2016

Covey, Thomas; Kovarik, Peter
US Patent Application 14/910032; 20160181082
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20160181082

Sample analysis systems and methods of use thereof
patent, July 2017

Cooks, Robert Graham; Baird, Zane; Wei, Pu
US Patent Document 9,704,700
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9704700

Low-Energy Ionic Collisions at Molecular Solids
journal, June 2012

Cyriac, Jobin; Pradeep, T.; Kang, H.
Chemical Reviews, Vol. 112, Issue 10, p. 5356-5411
https://doi.org/10.1021/cr200384k

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow
journal, December 2011

Wissdorf, Walter; Pohler, Larissa; Klee, Sonja
Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 2, p. 397-406
https://doi.org/10.1007/s13361-011-0290-x

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment
journal, January 2012

Badu-Tawiah, Abraham K.; Cyriac, Jobin; Cooks, R. Graham
Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 5, p. 842-849
https://doi.org/10.1007/s13361-012-0337-7

Ion focusing
patent, November 2015

Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping
US Patent Document 9,184,038
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/9184038

Practical implications of some recent studies in electrospray ionization fundamentals
journal, January 2001

Cech, Nadja B.; Enke, Christie G.
Mass Spectrometry Reviews, Vol. 20, Issue 6, p. 362-387
https://doi.org/10.1002/mas.10008

Development of an electrospray approach to deposit complex molecules on plasma modified surfaces
journal, November 2003

Kitching, K. J.; Lee, H-N.; Elam, W. T.
Review of Scientific Instruments, Vol. 74, Issue 11, p. 4832-4839
https://doi.org/10.1063/1.1618013

Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions
journal, September 2011

Sokol, Ewa; Noll, Robert J.; Cooks, R. Graham
International Journal of Mass Spectrometry, Vol. 306, Issue 2-3, p. 187-195
https://doi.org/10.1016/j.ijms.2010.10.019

Image Mapping Spectrometers
patent-application, November 2011

Tkaczyk, Thomas S.; Kester, Robert T.; Gao, Liang
US Patent Application 13/127401; 20110285995
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20110285995

Microengineered vacuum interface for an ionization system
patent, August 2010

Syms, Richard; Moseley, Richard William
US Patent Document 7,786,434
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7786434

Systems and methods for transfer of ions for analysis
patent, April 2013

Ouyang, Zheng; Cooks, Robert Graham; Garimella, Sandilya Venkata
US Patent Document 8,410,431
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8410431

Laminated tube for the transport of charged particles contained in a gaseous medium
patent, September 2005

Willoughby, Ross C.; Sheehan, Edward William
US Patent Document 6,943,347
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6943347

Coupling Differential Mobility Based Ambient Pressure Ion Prefiltering and Ion Focusing at Low Flow Rates for a Portable Mass Spectrometer
patent-application, May 2011

Miller, Raanan A.; Nazarov, Erkinjon G.; Morris, C. James
US Patent Application 12/856366; 20110101214
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20110101214

Image mapping spectrometers
patent, February 2014

Tkaczyk, Tomasz; Kester, Robert Timothy; Gao, Liang
US Patent Document 8,654,328
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8654328

Soft Landing of Complex Molecules on Surfaces
journal, July 2011

Johnson, Grant E.; Hu, Qichi; Laskin, Julia
Annual Review of Analytical Chemistry, Vol. 4, Issue 1, p. 83-104
https://doi.org/10.1146/annurev-anchem-061010-114028

Method and device for non-contact sampling and detection
patent, September 2009

Karpetsky, Timothy P.
US Patent Document 7,586,092
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7586092

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays
journal, February 2007

Martinez, Andres W.; Phillips, Scott T.; Butte, Manish J.
Angewandte Chemie International Edition, Vol. 46, Issue 8, p. 1318-1320
https://doi.org/10.1002/anie.200603817

Electrospray ionization ion source with tunable charge reduction
patent-application, May 2007

Frey, Brian L.; Smith, Lloyd M.; Westphall, Michael S.
US Patent Application 11/272450; 20070102634
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20070102634

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine
journal, March 2000

Karas, M.; Bahr, U.; Dülcks, T.
Fresenius' Journal of Analytical Chemistry, Vol. 366, Issue 6-7, p. 669-676
https://doi.org/10.1007/s002160051561

Discontinuous Atmospheric Pressure Interface
patent-application, December 2010

Ouyang, Zheng; Gao, Liang; Cooks, Robert Graham
US Patent Document 12/622776; 20100301209
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100301209

The ion funnel: Theory, implementations, and applications
journal, April 2009

Kelly, Ryan T.; Tolmachev, Aleksey V.; Page, Jason S.
Mass Spectrometry Reviews, Vol. 29, Issue 2, p. 294-312
https://doi.org/10.1002/mas.20232

Sampling Wand for an Ion Trap Mass Spectrometer
journal, March 2011

Hou, Keyong; Xu, Wei; Xu, Jian
Analytical Chemistry, Vol. 83, Issue 5, p. 1857-1861
https://doi.org/10.1021/ac102962e

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition
journal, September 2010

Thontasen, Nicha; Levita, Giacomo; Malinowski, Nikola
The Journal of Physical Chemistry C, Vol. 114, Issue 41, p. 17768-17772
https://doi.org/10.1021/jp106123q

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry
journal, October 2009

Gao, Liang; Li, Guangtao; Cyriac, Jobin
The Journal of Physical Chemistry C, Vol. 114, Issue 12, p. 5331-5337
https://doi.org/10.1021/jp904960t

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules
journal, July 2011

Cyriac, Jobin; Li, Guangtao; Cooks, R. Graham
Analytical Chemistry, Vol. 83, Issue 13, p. 5114-5121
https://doi.org/10.1021/ac200118f

Spherical side-to-side FAIMS
patent-application, December 2003

Guevremont, Roger; Purves, Randy; Barnett, David
US Patent Application 10/359644; 20030226965
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030226965

From Ions In Solution To Ions In The Gas Phase
journal, November 1993

Kebarle, Paul; Tang, Liang
Analytical Chemistry, Vol. 65, Issue 22, p. 972A-986A
https://doi.org/10.1021/ac00070a715

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
journal, October 2004

Takats, Z.
Science, Vol. 306, Issue 5695, p. 471-473
https://doi.org/10.1126/science.1104404

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations
journal, August 2012

Badu-Tawiah, Abraham K.; Li, Anyin; Jjunju, Fred P. M.
Angewandte Chemie International Edition, Vol. 51, Issue 37, p. 9417-9421
https://doi.org/10.1002/anie.201205044

Handheld Rectilinear Ion Trap Mass Spectrometer
journal, September 2006

Gao, Liang; Song, Qingyu; Patterson, Garth E.
Analytical Chemistry, Vol. 78, Issue 17, p. 5994-6002
https://doi.org/10.1021/ac061144k

The growth and modification of materials via ion–surface processing
journal, March 2002

Hanley, Luke; Sinnott, Susan B.
Surface Science, Vol. 500, Issue 1-3, p. 500-522
https://doi.org/10.1016/S0039-6028(01)01528-X

Three-dimensional microfluidic devices fabricated in layered paper and tape
journal, December 2008

Martinez, A. W.; Phillips, S. T.; Whitesides, G. M.
Proceedings of the National Academy of Sciences, Vol. 105, Issue 50, p. 19606-19611
https://doi.org/10.1073/pnas.0810903105

Discontinuous atmospheric pressure interface
patent, November 2012

Ouyang, Zheng; Gao, Liang; Cooks, Robert Graham
US Patent Document 8,304,718
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8304718

A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer
journal, April 1997

Tolmachev, A. V.; Chernushevich, I. V.; Dodonov, A. F.
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 124, Issue 1
https://doi.org/10.1016/S0168-583X(97)00068-2

Direct Sample Analysis Ion Source
patent-application, December 2012

Whitehouse, Craig M.
US Patent Application 13/487037; 20120312980
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20120312980

FAIMS apparatus having plural ion inlets and method therefore
patent-application, November 2004

Guevremont, Roger; Purves, Randy; Barnett, David
US Patent Application 10/861518; 20040232326
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20040232326

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS
journal, November 2009

Prasad, Satendra; Tang, Keqi; Manura, David
Analytical Chemistry, Vol. 81, Issue 21, p. 8749-8757
https://doi.org/10.1021/ac900880v

Helical Peptide Arrays on Self-Assembled Monolayer Surfaces through Soft and Reactive Landing of Mass-Selected Ions
journal, August 2008

Wang, Peng; Laskin, Julia
Angewandte Chemie International Edition, Vol. 47, Issue 35, p. 6678-6680
https://doi.org/10.1002/anie.200801366

Design and Characterization of a Multisource Hand-Held Tandem Mass Spectrometer
journal, October 2008

Gao, Liang; Sugiarto, Andy; Harper, Jason D.
Analytical Chemistry, Vol. 80, Issue 19, p. 7198-7205
https://doi.org/10.1021/ac801275x

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments
journal, September 2008

Lai, Hanh; McJunkin, Timothy R.; Miller, Carla J.
International Journal of Mass Spectrometry, Vol. 276, Issue 1, p. 1-8
https://doi.org/10.1016/j.ijms.2008.06.011

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications
journal, March 2003

Kogelschatz, Ulrich
Plasma Chemistry and Plasma Processing, Vol. 23, Issue 1, p. 1-46
https://doi.org/10.1023/A:1022470901385

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects
journal, March 2012

Badu-Tawiah, Abraham K.; Campbell, Dahlia I.; Cooks, R. Graham
Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 6, p. 1077-1084
https://doi.org/10.1007/s13361-012-0365-3

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters
journal, February 2010

Li, Guangtao; Cyriac, Jobin; Gao, Liang
Surface and Interface Analysis, Vol. 43, Issue 1-2, p. 498-501
https://doi.org/10.1002/sia.3161

Segmented side-to-side FAIMS
patent-application, July 2005

Guevremont, Roger; Purves, Randy; Barnett, David
US Patent Application 10/503714; 20050151072
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20050151072

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au₈ clusters
journal, May 2007

Lim, Dong Chan; Dietsche, Rainer; Bubek, Moritz
Chemical Physics Letters, Vol. 439, Issue 4-6, p. 364-368
https://doi.org/10.1016/j.cplett.2007.04.001

Integrated ion focusing and gating optics for ion trap mass spectrometer
patent-application,

Wells, Gregory J.; Schachterle, Steen D.
US Patent Application 10/066124; 20030141449
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20030141449

Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation
patent-application, December 2002

Smith, Richard D.; Kim, Taeman; Tang, Keqi
US Patent Application 09/860721; 20020185606
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20020185606

Electrospray ionization for mass spectrometry of large biomolecules
journal, October 1989

Fenn, J.; Mann, M.; Meng, C.
Science, Vol. 246, Issue 4926, p. 64-71
https://doi.org/10.1126/science.2675315

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface
journal, September 2007

Page, Jason S.; Kelly, Ryan T.; Tang, Keqi
Journal of the American Society for Mass Spectrometry, Vol. 18, Issue 9, p. 1582-1590
https://doi.org/10.1016/j.jasms.2007.05.018

Method and system for desorption electrospray ionization
patent, February 2008

Takats, Zoltan; Gologan, Bogdan; Wiseman, Justin
US Patent Document 7,335,897
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7335897

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper
journal, May 2008

Bruzewicz, Derek A.; Reches, Meital; Whitesides, George M.
Analytical Chemistry, Vol. 80, Issue 9, p. 3387-3392
https://doi.org/10.1021/ac702605a

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition
journal, September 2008

Wroble, Amanda T.; Wildeman, Jurjen; Asunskis, Daniel J.
Thin Solid Films, Vol. 516, Issue 21, p. 7386-7392
https://doi.org/10.1016/j.tsf.2008.02.024

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry
journal, June 2006

Cotte-Rodríguez, Ismael; Cooks, R. Graham
Chem. Commun., Issue 28, p. 2968-2970
https://doi.org/10.1039/B606020J

Electro-Dynamic or Electro-Static Lens Coupled to a Stacked Ring Ion Guide
patent-application, April 2010

Splendore, Maurizio A.; Wouters, Eloy R.; Senko, Michael W.
US Patent Application 12/252013; 20100090104
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/20100090104

Paper-Based Microfluidic Devices by Plasma Treatment
journal, December 2008

Li, Xu; Tian, Junfei; Nguyen, Thanh
Analytical Chemistry, Vol. 80, Issue 23, p. 9131-9134
https://doi.org/10.1021/ac801729t

Current status of droplet evaporation in turbulent flows
journal, July 2006

Birouk, M.; Gokalp, I.
Progress in Energy and Combustion Science, Vol. 32, Issue 4, p. 408-423
https://doi.org/10.1016/j.pecs.2006.05.001

Ion transport device and modes of operation thereof
patent, August 2010

Senko, Michael W.; Kovtoun, Viatcheslav V.; Atherton, Paul R.
US Patent Document 7,781,728
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7781728

Similar Records in DOE Patents and OSTI.GOV collections:

Ion focusing

Patent Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which ismore » « less
Full Text Available
Ion focusing

Patent Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which ismore » « less
Full Text Available
Method for fabricating superconducting devices using a focused ion beam

Patent Cybart, Shane A.; Cho, Ethan Y.; Dynes, Robert C.; ...

Nano-scale junctions, wires, and junction arrays are created by using a focused high-energy ion beam to direct-write insulating or poorly conducting barriers into thin films of materials that are sensitive to disorder, including superconductors, ferromagnetic materials and semiconductors.
Full Text Available
Periodic field focusing ion mobility spectrometer

Patent Gillig, Kent J.; Russell, David H.

This invention is generally in the field of improved ion mobility spectrometry. The improvement lies in the use of periodic focusing electric fields that minimize the spatial spread of the migrating ions by keeping them in a tight radius about the axis of travel. The resulting enhancement in sensitivity is accomplished without a concomitant loss in resolution as would normally be expected when non-linear fields are used.
Full Text Available
Ion focusing device

Patent Ibrahim, Yehia M.; Smith, Richard D.

Apparatus include a plurality of electrode arrangements spaced apart from each other opposite an ion propagation axis and defining an ion transfer channel that extends along the ion propagation axis that tapers between an input end that is situated to receive ions and an output end that is situated to couple the received ions to an input end of an ion guide. Methods include positioning a plurality of electrode arrangements at oblique angles opposite an ion propagation axis so as to form a ion transfer channel that tapers between an input end and an output end, and coupling the outputmore » « less
Full Text Available

Similar Records

Title: Ion focusing

Abstract

Citation Formats

Method and apparatus for aerodynamic ion focusing patent, January 2006

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing journal, November 2011

SIMION ion optics simulations at atmospheric pressure journal, June 2005

Apparatus and method for focusing ions and charged particles at atmospheric pressure patent, June 2004

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper journal, September 2008

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition journal, April 2005

Apparatus and methods for analyzing ions patent, January 2013

Processing of giant graphene molecules by soft-landing mass spectrometry journal, March 2006

Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method patent-application, June 2012

System and method for the preparation of arrays of biological or other molecules patent, April 2008

Phosphor and manufacturing method of the same, and light emitting device using the phosphor patent-application, October 2006

Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces journal, February 2006

Atmospheric pressure interface ion source and mass spectrometer patent-application, May 2014

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface journal, August 2005

Novel purified polypeptides from Pseudomonas aeruginosa patent-application, November 2005

Ion focusing patent-application, June 2016

Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids journal, January 2005

Ambient Ionization Mass Spectrometry journal, June 2010

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer journal, February 2012

Ion focusing patent, January 2017

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions journal, April 2005

Charge reduction electrospray ionization ion source patent-application, September 2002

Enhanced Spray Formation for Liquid Samples patent-application, June 2016

Sample analysis systems and methods of use thereof patent, July 2017

Low-Energy Ionic Collisions at Molecular Solids journal, June 2012

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow journal, December 2011

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment journal, January 2012

Ion focusing patent, November 2015

Practical implications of some recent studies in electrospray ionization fundamentals journal, January 2001

Development of an electrospray approach to deposit complex molecules on plasma modified surfaces journal, November 2003

Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions journal, September 2011

Image Mapping Spectrometers patent-application, November 2011

Microengineered vacuum interface for an ionization system patent, August 2010

Systems and methods for transfer of ions for analysis patent, April 2013

Laminated tube for the transport of charged particles contained in a gaseous medium patent, September 2005

Coupling Differential Mobility Based Ambient Pressure Ion Prefiltering and Ion Focusing at Low Flow Rates for a Portable Mass Spectrometer patent-application, May 2011

Image mapping spectrometers patent, February 2014

Soft Landing of Complex Molecules on Surfaces journal, July 2011

Method and device for non-contact sampling and detection patent, September 2009

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays journal, February 2007

Electrospray ionization ion source with tunable charge reduction patent-application, May 2007

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine journal, March 2000

Discontinuous Atmospheric Pressure Interface patent-application, December 2010

The ion funnel: Theory, implementations, and applications journal, April 2009

Sampling Wand for an Ion Trap Mass Spectrometer journal, March 2011

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition journal, September 2010

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry journal, October 2009

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules journal, July 2011

Spherical side-to-side FAIMS patent-application, December 2003

From Ions In Solution To Ions In The Gas Phase journal, November 1993

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization journal, October 2004

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations journal, August 2012

Handheld Rectilinear Ion Trap Mass Spectrometer journal, September 2006

The growth and modification of materials via ion–surface processing journal, March 2002

Three-dimensional microfluidic devices fabricated in layered paper and tape journal, December 2008

Discontinuous atmospheric pressure interface patent, November 2012

A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer journal, April 1997

Direct Sample Analysis Ion Source patent-application, December 2012

FAIMS apparatus having plural ion inlets and method therefore patent-application, November 2004

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS journal, November 2009

Helical Peptide Arrays on Self-Assembled Monolayer Surfaces through Soft and Reactive Landing of Mass-Selected Ions journal, August 2008

Design and Characterization of a Multisource Hand-Held Tandem Mass Spectrometer journal, October 2008

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments journal, September 2008

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications journal, March 2003

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects journal, March 2012

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters journal, February 2010

Segmented side-to-side FAIMS patent-application, July 2005

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au8 clusters journal, May 2007

Integrated ion focusing and gating optics for ion trap mass spectrometer patent-application,

Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation patent-application, December 2002

Electrospray ionization for mass spectrometry of large biomolecules journal, October 1989

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface journal, September 2007

Method and system for desorption electrospray ionization patent, February 2008

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper journal, May 2008

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition journal, September 2008

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry journal, June 2006

Electro-Dynamic or Electro-Static Lens Coupled to a Stacked Ring Ion Guide patent-application, April 2010

Method and apparatus for aerodynamic ion focusing
patent, January 2006

Redox chemistry in thin layers of organometallic complexes prepared using ion soft landing
journal, November 2011

SIMION ion optics simulations at atmospheric pressure
journal, June 2005

Apparatus and method for focusing ions and charged particles at atmospheric pressure
patent, June 2004

Inkjet-Printed Microfluidic Multianalyte Chemical Sensing Paper
journal, September 2008

Photoemission Studies of Polythiophene and Polyphenyl Films Produced via Surface Polymerization by Ion-Assisted Deposition
journal, April 2005

Apparatus and methods for analyzing ions
patent, January 2013

Processing of giant graphene molecules by soft-landing mass spectrometry
journal, March 2006

Efficient Atmospheric Pressure Interface for Mass Spectrometers and Method
patent-application, June 2012

System and method for the preparation of arrays of biological or other molecules
patent, April 2008

Phosphor and manufacturing method of the same, and light emitting device using the phosphor
patent-application, October 2006

Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces
journal, February 2006

Atmospheric pressure interface ion source and mass spectrometer
patent-application, May 2014

Preparative Soft and Reactive Landing of Multiply Charged Protein Ions on a Plasma-Treated Metal Surface
journal, August 2005

Novel purified polypeptides from Pseudomonas aeruginosa
patent-application, November 2005

Ion focusing
patent-application, June 2016

Electrospray-assisted laser desorption/ionization mass spectrometry for direct ambient analysis of solids
journal, January 2005

Ambient Ionization Mass Spectrometry
journal, June 2010

Gas-flow assisted ion transfer for mass spectrometry: Flow assisted ion transfer
journal, February 2012

Ion focusing
patent, January 2017

Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005

Charge reduction electrospray ionization ion source
patent-application, September 2002

Enhanced Spray Formation for Liquid Samples
patent-application, June 2016

Sample analysis systems and methods of use thereof
patent, July 2017

Low-Energy Ionic Collisions at Molecular Solids
journal, June 2012

Simulation of Ion Motion at Atmospheric Pressure: Particle Tracing Versus Electrokinetic Flow
journal, December 2011

Reactions of Organic Ions at Ambient Surfaces in a Solvent-Free Environment
journal, January 2012

Ion focusing
patent, November 2015

Practical implications of some recent studies in electrospray ionization fundamentals
journal, January 2001

Development of an electrospray approach to deposit complex molecules on plasma modified surfaces
journal, November 2003

Miniature mass spectrometer equipped with electrospray and desorption electrospray ionization for direct analysis of organics from solids and solutions
journal, September 2011

Image Mapping Spectrometers
patent-application, November 2011

Microengineered vacuum interface for an ionization system
patent, August 2010

Systems and methods for transfer of ions for analysis
patent, April 2013

Laminated tube for the transport of charged particles contained in a gaseous medium
patent, September 2005

Coupling Differential Mobility Based Ambient Pressure Ion Prefiltering and Ion Focusing at Low Flow Rates for a Portable Mass Spectrometer
patent-application, May 2011

Image mapping spectrometers
patent, February 2014

Soft Landing of Complex Molecules on Surfaces
journal, July 2011

Method and device for non-contact sampling and detection
patent, September 2009

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays
journal, February 2007

Electrospray ionization ion source with tunable charge reduction
patent-application, May 2007

Nano-electrospray ionization mass spectrometry: addressing analytical problems beyond routine
journal, March 2000

Discontinuous Atmospheric Pressure Interface
patent-application, December 2010

The ion funnel: Theory, implementations, and applications
journal, April 2009

Sampling Wand for an Ion Trap Mass Spectrometer
journal, March 2011

Grafting Crown Ether Alkali Host−Guest Complexes at Surfaces by Electrospray Ion Beam Deposition
journal, September 2010

Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry
journal, October 2009

Vibrational Spectroscopy and Mass Spectrometry for Characterization of Soft Landed Polyatomic Molecules
journal, July 2011

Spherical side-to-side FAIMS
patent-application, December 2003

From Ions In Solution To Ions In The Gas Phase
journal, November 1993

Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
journal, October 2004

Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations
journal, August 2012

Handheld Rectilinear Ion Trap Mass Spectrometer
journal, September 2006

The growth and modification of materials via ion–surface processing
journal, March 2002

Three-dimensional microfluidic devices fabricated in layered paper and tape
journal, December 2008

Discontinuous atmospheric pressure interface
patent, November 2012

A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer
journal, April 1997

Direct Sample Analysis Ion Source
patent-application, December 2012

FAIMS apparatus having plural ion inlets and method therefore
patent-application, November 2004

Simulation of Ion Motion in FAIMS through Combined Use of SIMION and Modified SDS
journal, November 2009

Helical Peptide Arrays on Self-Assembled Monolayer Surfaces through Soft and Reactive Landing of Mass-Selected Ions
journal, August 2008

Design and Characterization of a Multisource Hand-Held Tandem Mass Spectrometer
journal, October 2008

The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments
journal, September 2008

Dielectric-Barrier Discharges: Their History, Discharge Physics, and Industrial Applications
journal, March 2003

Reactions of Microsolvated Organic Compounds at Ambient Surfaces: Droplet Velocity, Charge State, and Solvent Effects
journal, March 2012

Molecular ion yield enhancement in static secondary ion mass spectrometry by soft landing of protonated water clusters
journal, February 2010

Segmented side-to-side FAIMS
patent-application, July 2005

Chemistry of mass-selected Au clusters deposited on sputter-damaged HOPG surfaces: The unique properties of Au₈ clusters
journal, May 2007

Integrated ion focusing and gating optics for ion trap mass spectrometer
patent-application,

Ionization source utilizing a jet disturber in combination with an ion funnel and method of operation
patent-application, December 2002

Electrospray ionization for mass spectrometry of large biomolecules
journal, October 1989

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface
journal, September 2007

Method and system for desorption electrospray ionization
patent, February 2008

Low-Cost Printing of Poly(dimethylsiloxane) Barriers To Define Microchannels in Paper
journal, May 2008

Growth of phenylene vinylene thin films via surface polymerization by ion-assisted deposition
journal, September 2008

Non-proximate detection of explosives and chemical warfare agent simulants by desorption electrospray ionization mass spectrometry
journal, June 2006

Electro-Dynamic or Electro-Static Lens Coupled to a Stacked Ring Ion Guide
patent-application, April 2010

Paper-Based Microfluidic Devices by Plasma Treatment
journal, December 2008

Current status of droplet evaporation in turbulent flows
journal, July 2006

Ion transport device and modes of operation thereof
patent, August 2010