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Title: Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same

A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: ##STR00001## wherein R.sub.1-R.sub.7 may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
Inventors:
; ; ; ; ; ;
Issue Date:
OSTI Identifier:
1457028
Assignee:
University of Southern California (Los Angeles, CA) DOESC
Patent Number(s):
9,987,380
Application Number:
13/549,309
Contract Number:
SC0002353
Resource Relation:
Patent File Date: 2012 Jul 13
Research Org:
Univ. of Southern California, Los Angeles, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English