Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same
Abstract
A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: ##STR00001## wherein R.sub.1-R.sub.7 may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Southern California, Los Angeles, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1457028
- Patent Number(s):
- 9987380
- Application Number:
- 13/549,309
- Assignee:
- University of Southern California (Los Angeles, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- DOE Contract Number:
- SC0002353
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2012 Jul 13
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Li, Zibo, Gabbai, Francois P., Conti, Peter S., Hudnall, Todd W., Lin, Tzu-Pin, Liu, Shuanglong, and Huang, Chiun-Wei. Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same. United States: N. p., 2018.
Web.
Li, Zibo, Gabbai, Francois P., Conti, Peter S., Hudnall, Todd W., Lin, Tzu-Pin, Liu, Shuanglong, & Huang, Chiun-Wei. Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same. United States.
Li, Zibo, Gabbai, Francois P., Conti, Peter S., Hudnall, Todd W., Lin, Tzu-Pin, Liu, Shuanglong, and Huang, Chiun-Wei. Tue .
"Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same". United States. https://www.osti.gov/servlets/purl/1457028.
@article{osti_1457028,
title = {Boron-based dual imaging probes, compositions and methods for rapid aqueous F-18 labeling, and imaging methods using same},
author = {Li, Zibo and Gabbai, Francois P. and Conti, Peter S. and Hudnall, Todd W. and Lin, Tzu-Pin and Liu, Shuanglong and Huang, Chiun-Wei},
abstractNote = {A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof: ##STR00001## wherein R.sub.1-R.sub.7 may be independently selected from hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, X is selected from the group consisting of C and N; and A is selected of hydrogen, halogen, hydroxy, alkoxy, nitro, substituted and unsubstituted amino, alkyl, cycloalkyl, carboxy, carboxylic acids and esters thereof, cyano, haloalkyl, aryl, including phenyl and aminophenyl, and heteroaryl.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {6}
}
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