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Title: DNA/RNA sequencing using a semiconducting nanopore

Abstract

The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.

Inventors:
; ;
Issue Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1456913
Patent Number(s):
9988677
Application Number:
14/735,898
Assignee:
Fleharty; Petsev; Dimiter N. ; Van Swol; Frank B.
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
DE-AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Jun 10
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Fleharty, Mark, Petsev, Dimiter N., and Van Swol, Frank B. DNA/RNA sequencing using a semiconducting nanopore. United States: N. p., 2018. Web.
Fleharty, Mark, Petsev, Dimiter N., & Van Swol, Frank B. DNA/RNA sequencing using a semiconducting nanopore. United States.
Fleharty, Mark, Petsev, Dimiter N., and Van Swol, Frank B. Tue . "DNA/RNA sequencing using a semiconducting nanopore". United States. https://www.osti.gov/servlets/purl/1456913.
@article{osti_1456913,
title = {DNA/RNA sequencing using a semiconducting nanopore},
author = {Fleharty, Mark and Petsev, Dimiter N. and Van Swol, Frank B.},
abstractNote = {The present disclosure provides novel apparatus including, though not necessarily limited to, biosensors utilizing semiconductor materials in electrolyte solutions and methods for using the same. The biosensors rely on a unique property wherein a charged body in the electrolyte solution produces a detectable change in the local conductivity of the semiconductor as the body approaches or travels near the semiconductor.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {6}
}

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Works referenced in this record:

Methods of Detecting Target Nucleic Acids
patent-application, November 2010