DNA-cell conjugates
Abstract
The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1438396
- Patent Number(s):
- 9969970
- Application Number:
- 15/057,604
- Assignee:
- THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2016 Mar 01
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Hsiao, Shih-Chia, Francis, Matthew B., Bertozzi, Carolyn, Mathies, Richard, Chandra, Ravi, Douglas, Erik, Twite, Amy, Toriello, Nicholas, and Onoe, Hiroaki. DNA-cell conjugates. United States: N. p., 2018.
Web.
Hsiao, Shih-Chia, Francis, Matthew B., Bertozzi, Carolyn, Mathies, Richard, Chandra, Ravi, Douglas, Erik, Twite, Amy, Toriello, Nicholas, & Onoe, Hiroaki. DNA-cell conjugates. United States.
Hsiao, Shih-Chia, Francis, Matthew B., Bertozzi, Carolyn, Mathies, Richard, Chandra, Ravi, Douglas, Erik, Twite, Amy, Toriello, Nicholas, and Onoe, Hiroaki. Tue .
"DNA-cell conjugates". United States. https://www.osti.gov/servlets/purl/1438396.
@article{osti_1438396,
title = {DNA-cell conjugates},
author = {Hsiao, Shih-Chia and Francis, Matthew B. and Bertozzi, Carolyn and Mathies, Richard and Chandra, Ravi and Douglas, Erik and Twite, Amy and Toriello, Nicholas and Onoe, Hiroaki},
abstractNote = {The present invention provides conjugates of DNA and cells by linking the DNA to a native functional group on the cell surface. The cells can be without cell walls or can have cell walls. The modified cells can be linked to a substrate surface and used in assay or bioreactors.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {5}
}
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