Systems and methods for integrating ion mobility and ion trap mass spectrometers
Abstract
Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1434509
- Patent Number(s):
- 9939409
- Application Number:
- 15/227,743
- Assignee:
- Battelle Memorial Institute (Richland, WA)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2016 Aug 03
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Ibrahim, Yehia M., Garimella, Sandilya, and Prost, Spencer A. Systems and methods for integrating ion mobility and ion trap mass spectrometers. United States: N. p., 2018.
Web.
Ibrahim, Yehia M., Garimella, Sandilya, & Prost, Spencer A. Systems and methods for integrating ion mobility and ion trap mass spectrometers. United States.
Ibrahim, Yehia M., Garimella, Sandilya, and Prost, Spencer A. Tue .
"Systems and methods for integrating ion mobility and ion trap mass spectrometers". United States. https://www.osti.gov/servlets/purl/1434509.
@article{osti_1434509,
title = {Systems and methods for integrating ion mobility and ion trap mass spectrometers},
author = {Ibrahim, Yehia M. and Garimella, Sandilya and Prost, Spencer A.},
abstractNote = {Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 10 00:00:00 EDT 2018},
month = {Tue Apr 10 00:00:00 EDT 2018}
}
Works referenced in this record:
Mass analysis of mobility selected ion populations
patent, July 2009
- Clowers, Brian H.; Hill, Jr., Herbert H.; Dwivedi, Prabha
- US Patent Document 7,560,688
Method and apparatus for coupling fast separations and slow detection systems
patent, February 2016
- Belov, Mikhail E.
- US Patent Document 9,269,548
Method and Apparatus for Coupling Fast Separation and Slow Detection Systems
patent-application, October 2012
- Belov, Mikhail E.
- US Patent Application 13/086244; 20120261564
Data Acquisition Modes for Ion Mobility Time-of-Flight Mass Spectrometry
patent-application, June 2013
- Ugarov, Michael
- US Patent Application 13/335059; 20130161506
Methods of Resolving Artifacts in Hadamard-Transformed Data
patent-application, January 2014
- Crowell, Kevin; Prost, Spencer A.
- US Patent Application 13/866686; 20140025314
Data Processing for Multiplexed Spectrometry
patent-application, December 2015
- Wang, JR., Jun
- US Patent Application 14/686569; 20150364305
Multiplexed Ion Mobility Spectrometry-Orthogonal Time-of-Flight Mass Spectrometry
journal, March 2007
- Belov, Mikhail E.; Buschbach, Michael A.; Prior, David C.
- Analytical Chemistry, Vol. 79, Issue 6, p. 2451-2462