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Title: Systems and methods for integrating ion mobility and ion trap mass spectrometers

Abstract

Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.

Inventors:
; ;
Issue Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1434509
Patent Number(s):
9939409
Application Number:
15/227,743
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Patent
Resource Relation:
Patent File Date: 2016 Aug 03
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Ibrahim, Yehia M., Garimella, Sandilya, and Prost, Spencer A.. Systems and methods for integrating ion mobility and ion trap mass spectrometers. United States: N. p., 2018. Web.
Ibrahim, Yehia M., Garimella, Sandilya, & Prost, Spencer A.. Systems and methods for integrating ion mobility and ion trap mass spectrometers. United States.
Ibrahim, Yehia M., Garimella, Sandilya, and Prost, Spencer A.. Tue . "Systems and methods for integrating ion mobility and ion trap mass spectrometers". United States. https://www.osti.gov/servlets/purl/1434509.
@article{osti_1434509,
title = {Systems and methods for integrating ion mobility and ion trap mass spectrometers},
author = {Ibrahim, Yehia M. and Garimella, Sandilya and Prost, Spencer A.},
abstractNote = {Described herein are examples of systems and methods for integrating IMS and MS systems. In certain examples, systems and methods for decoding double multiplexed data are described. The systems and methods can also perform multiple refining procedures in order to minimize the demultiplexing artifacts. The systems and methods can be used, for example, for the analysis of proteomic and petroleum samples, where the integration of IMS and high mass resolution are used for accurate assignment of molecular formulae.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {4}
}

Works referenced in this record:

Mass analysis of mobility selected ion populations
patent, July 2009


Method and Apparatus for Coupling Fast Separation and Slow Detection Systems
patent-application, October 2012


Data Acquisition Modes for Ion Mobility Time-of-Flight Mass Spectrometry
patent-application, June 2013


Methods of Resolving Artifacts in Hadamard-Transformed Data
patent-application, January 2014


Data Processing for Multiplexed Spectrometry
patent-application, December 2015


Multiplexed Ion Mobility Spectrometry-Orthogonal Time-of-Flight Mass Spectrometry
journal, March 2007