DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Biological production of organic compounds

Abstract

Methods of producing ethylene oxide and ethylene glycol are disclosed herein. Ethylene produced by cyanobacteria engineered to express ethylene-forming enzymes may be converted to ethylene oxide by bacteria engineered to express a monooxygenase enzyme. Ethylene oxide may be converted to ethylene glycol by exposure to an acidic solution. The methods may be performed in a bioreactor.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1426794
Patent Number(s):
9914947
Application Number:
15/054,868
Assignee:
Alliance for Sustainable Energy, LLC (Golden, CO)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
AC36-08GO28308
Resource Type:
Patent
Resource Relation:
Patent File Date: 2016 Feb 26
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Yu, Jianping, Wang, Bo, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, and Seibert, Michael. Biological production of organic compounds. United States: N. p., 2018. Web.
Yu, Jianping, Wang, Bo, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, & Seibert, Michael. Biological production of organic compounds. United States.
Yu, Jianping, Wang, Bo, Paddock, Troy, Carrieri, Damian, Maness, Pin-Ching, and Seibert, Michael. Tue . "Biological production of organic compounds". United States. https://www.osti.gov/servlets/purl/1426794.
@article{osti_1426794,
title = {Biological production of organic compounds},
author = {Yu, Jianping and Wang, Bo and Paddock, Troy and Carrieri, Damian and Maness, Pin-Ching and Seibert, Michael},
abstractNote = {Methods of producing ethylene oxide and ethylene glycol are disclosed herein. Ethylene produced by cyanobacteria engineered to express ethylene-forming enzymes may be converted to ethylene oxide by bacteria engineered to express a monooxygenase enzyme. Ethylene oxide may be converted to ethylene glycol by exposure to an acidic solution. The methods may be performed in a bioreactor.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {3}
}

Works referenced in this record:

Process and apparatus for removing ethylene oxide from gas compositions
patent, September 1978


Ethanol production by microorganisms
patent, June 2011


Engineered CO2 fixing microorganisms producing carbon-based products of interest
patent, July 2011


Ethanol production in microorganisms
patent, November 2011


Ethanol production in microorganisms
patent, July 2012


Engineered CO2 fixing microorganisms producing carbon-based products of interest
patent, July 2012


Ethanol production in microorganisms
patent, June 2013


Biological production of organic compounds
patent, April 2016


Genetically Modified Cyanobacteria for the Production of Ethanol
patent-application, March 2010


Modified Photosynthetic Microorganisms With Reduced Glycogen and Their Use in Producing Carbon-Based Products
patent-application, July 2010


Molecular Approaches for the Optimization of Biofuel Production
patent-application, December 2010


Organisms for the Production of Isopropanol, N-Butanol, and Isobutanol
patent-application, December 2010


Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest
patent-application, January 2011


Modified Photosynthetic Microorganisms for Producing Lipids
patent-application, October 2011


Method for the Preparation of Diols
patent-application, December 2011


Microorganisms and Methods for the Production of Ethylene Glycol
patent-application, December 2011


Engineered CO2 Fixing Microorganisms Producing Carbon-Based Products of Interest
patent-application, May 2012


Biofuel From Recombinant Oleaginous Algae Using Sugar Carbon Sources
patent-application, June 2012


Genetically Engineered Cyanobacteria
patent-application, November 2012


Metabolically Engineered Organisms for the Production of Added Value Bio-Products
patent-application, May 2013


Biological Production of Organic Compounds
patent-application, August 2013


Biocatalytic conversion of ethylene to ethylene oxide using an engineered toluene monooxygenase
journal, January 2015


Photo-catalytic conversion of carbon dioxide to organic acids by a recombinant cyanobacterium incapable of glycogen storage
journal, January 2012


Glycogen content and nitrogenase activity in Anabaena variabilis
journal, December 1984


Heterologous expression of the gene for the ethylene-forming enzyme from Pseudomonas syringae in the cyanobacterium Synechococcus
journal, January 1994


Changes in photosynthesis and pigmentation in an agp deletion mutant of the cyanobacterium Synechocystis sp.
journal, January 2003


Sucrose accumulation in salt-stressed cells of agp gene deletion-mutant in cyanobacterium Synechocystis sp. PCC 6803
journal, January 2003


Carbohydrate Metabolism in Mutants of the Cyanobacterium Synechococcus elongatus PCC 7942 Defective in Glycogen Synthesis
journal, April 2010


Construction and analysis of a recombinant cyanobacterium expressing a chromosomally inserted gene for an ethylene-forming enzyme at the psbAI locus
journal, January 2003


Sustained photosynthetic conversion of CO2 to ethylene in recombinant cyanobacterium Synechocystis 6803
journal, January 2012


Modification of carbon partitioning to enhance PHB production in Synechocystis sp. PCC6803
journal, May 2002


Phosphoketolase pathway contributes to carbon metabolism in cyanobacteria
journal, December 2015