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Title: Engineered microbes and methods for microbial oil overproduction from cellulosic materials

The invention relates to engineering microbial cells for utilization of cellulosic materials as a carbon source, including xylose.
Inventors:
;
Issue Date:
OSTI Identifier:
1418983
Assignee:
Massachusetts Institute of Technology (Cambridge, MA) ARPA-E
Patent Number(s):
9,879,248
Application Number:
14/817,489
Contract Number:
AR0000059
Resource Relation:
Patent File Date: 2015 Aug 04
Research Org:
Massachusetts Institute of Technology, Cambridge, MA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
09 BIOMASS FUELS; 59 BASIC BIOLOGICAL SCIENCES

Other works cited in this record:

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Yarrowia lipolytica as a model for bio-oil production
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Selection of Direct Transesterification as the Preferred Method for Assay of Fatty Acid Content of Microalgae
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Engineering yeasts for xylose metabolism
journal, June 2006

DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Δsnf2 disruptant of Saccharomyces cerevisiae
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Comparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiae
journal, January 2007
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Minimal metabolic engineering of for efficient anaerobic xylose fermentation a proof of principle
journal, March 2004

Ethanol production from xylose in engineered Saccharomyces cerevisiae strains: current state and perspectives
journal, July 2009
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Accumulation of a Cocoa-Butter-Like Lipid by Yarrowia lipolytica Cultivated on Agro-Industrial Residues
journal, February 2003
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Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture
journal, March 2002

Single cell oil production by Yarrowia lipolytica growing on an industrial derivative of animal fat in batch cultures
journal, March 2002
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The use of Yarrowia lipolytica to reduce pollution in olive mill wastewaters
journal, October 1997

Screening of yeasts for growth on crude glycerol and optimization of biomass production
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Lipid production from Yarrowia lipolytica Po1g grown in sugarcane bagasse hydrolysate
journal, October 2011
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  • DOI: 10.1016/j.biortech.2011.06.047

A molecular transporter engineering approach to improving xylose catabolism in Saccharomyces cerevisiae
journal, July 2012

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