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Title: Filtration device for rapid separation of biological particles from complex matrices

Methods and systems for filtering of biological particles are disclosed. Filtering membranes separate adjacent chambers. Through osmotic or electrokinetic processes, flow of particles is carried out through the filtering membranes. Cells, viruses and cell waste can be filtered depending on the size of the pores of the membrane. A polymer brush can be applied to a surface of the membrane to enhance filtering and prevent fouling.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1416743
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA) LLNL
Patent Number(s):
9,861,939
Application Number:
14/874,326
Contract Number:
AC52-07NA27344
Resource Relation:
Patent File Date: 2015 Oct 02
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

Other works cited in this record:

Magnetically Responsive Membranes
patent-application, August 2014

Rapid detection of bacterial cell from whole blood: Integration of DNA sample preparation into single micro-PCR chip
journal, May 2011
  • Hwang, Kyu-Youn; Jeong, Sung-Young; Kim, Young-Rok
  • Sensors and Actuators B: Chemical, Vol. 154, Issue 1, p. 46-51
  • DOI: 10.1016/j.snb.2009.11.005

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